| Purewave Form Ltd | Professional & scientific | 2024 |
| Purewave Group Ltd | Professional & scientific | 2026 |
| Purewave Holdings Limited | Financial services | 2026 |
| PWG Solutions Ltd | Information & communication | 2026 |
| Quantum Live Productions Ltd | Professional & scientific | 2024 |
| R & B Tyre Services Limited | Wholesale & retail | 2010 |
| R & R Consulting Services Ltd | Administrative & support | 2026 |
| R Carlton Electrical Services Ltd | Construction | 2018 |
| R L Spencer Limited | Information & communication | 2010 |
| R&D Plumbing & Heating Ltd | Professional & scientific | 2015 |
| Rachael Sidley Psychotherapy Ltd | Health & social care | 2021 |
| Rainbow Day Nursery Haslington Limited | Health & social care | 2015 |
| Rainbow Day Nursery Middlewich Limited | Education | 2009 |
| Rainbow Private Nursery School Limited | Education | 1999 |
| Raja That Limited | Financial services | 2020 |
| Ralfia Properties Ltd | Real estate | 2019 |
| RAM Burnley Ltd | Hospitality | 2024 |
| Range Roofing and Cladding Limited | Construction | 1993 |
| RAY Housing Ltd | Real estate | 2024 |
| RBJ Quyken Limited | Professional & scientific | 2023 |
| RC Plant Limited | Administrative & support | 2023 |
| RDI Projects Ltd | Real estate | 2024 |
| RDI Properties Ltd | Real estate | 2017 |
| RDI Property (UK) Limited | Real estate | 2014 |
| Red Hair Design Limited | Other services | 2014 |
| Red Lantern Digital Media Limited | Manufacturing | 2012 |
| Redberry Estates Ltd | Real estate | 2025 |
| Redfox Operations Limited | Financial services | 2025 |
| Reel Vision Limited | Information & communication | 2009 |
| Repoly UK Ltd | Manufacturing | 2025 |
| Report Masters Limited | Professional & scientific | 2023 |
| Resin Surface Installations Limited | Construction | 2011 |
| Resourced Exchange Limited | Information & communication | 2024 |
| RGA Drive Limited | Transport & logistics | 2020 |
| Riley Harvey Management Services Ltd | Professional & scientific | 2013 |
| Rippleretail Limited | Wholesale & retail | 2025 |
| Rise Element Coaching Ltd | Professional & scientific | 2024 |
| Rita & Co Residential Ltd | Real estate | 2020 |
| RJ & FM Farmers Limited | Agriculture & fishing | 2025 |
| RMS Ambulance Limited | Professional & scientific | 2023 |
| Roberts Family Investment Company Limited | Financial services | 2021 |
| ROC Angels Ltd | Other services | 2024 |
| Rockleaze Developments Limited | Construction | 2024 |
| Rockleaze Real Estate Limited | Real estate | 2008 |
| Rofram Solutions Ltd | Professional & scientific | 2011 |
| Roll-Ezy Limited | Manufacturing | 1994 |
| Rompers Nursery Limited | Education | 2017 |
| Rope Green Farm Day Nursery Limited | Health & social care | 2012 |
| Rosada Ltd | Education | 2024 |
| RS Process Safety Limited | Professional & scientific | 2012 |
| RTG Partners Ltd | Information & communication | 2023 |
| Rules of the Road Limited | Transport & logistics | 2019 |
| Rusty Cans Music Ltd | Information & communication | 2022 |
| Rylands Properties (Warrington) Limited | Real estate | 2015 |
| Rylands Recreation Trading Limited | Arts & recreation | 2019 |
| SAC + Co Creative Limited | Professional & scientific | 2020 |
| SAC + Co Property Ltd | Real estate | 2022 |
| Sadala Properties Ltd | Other services | 2026 |
| Sadiq Consulting Limited | Professional & scientific | 2024 |
| Safria Designs Ltd | Manufacturing | 2021 |
| Sage Interiors Ltd | Professional & scientific | 2024 |
| Sakaricc UK Ltd | Real estate | 2025 |
| Sakarma Limited | Administrative & support | 2010 |
| Samantha Fisher Ltd | Professional & scientific | 2025 |
| Samantix Consultancy Limited | Information & communication | 2025 |
| Saml Limited | Real estate | 2016 |
| Sanders Day Nurseries Limited | Education | 2008 |
| Sandy Group Holdings Ltd | Financial services | 2025 |
| Sarah Harrison Accountancy Services Limited | Professional & scientific | 2018 |
| Satya Sanctuary Limited | Arts & recreation | 2024 |
| Sauna & Chill Ltd | Arts & recreation | 2025 |
| SBS Environmental Ltd | Professional & scientific | 2020 |
| School Appeal Limited | Education | 2018 |
| SD & K Ltd | Real estate | 2019 |
| Sedgwick Wealth Management Limited | Financial services | 2010 |
| Seer Property Investments Ltd | Real estate | 2012 |
| Send Recruitment Limited | Administrative & support | 2016 |
| Serene Consultants Limited | Health & social care | 2005 |
| Sharper Trading Limited | Wholesale & retail | 2017 |
| Shine Childcare Limited | Education | 2004 |
| Shine Holdings Limited | Financial services | 2023 |
| Showreal Ltd | Information & communication | 2005 |
| Sicarro Ltd | Wholesale & retail | 2021 |
| Sigma Teaching Resources Limited | Education | 2010 |
| Simon Bentley Logistics Limited | Transport & logistics | 2023 |
| Simply Waste Consultants Limited | Water & waste | 2019 |
| SJC Physiotherapy Ltd | Health & social care | 2023 |
| SK Overseas Ltd | Professional & scientific | 2013 |
| Skin & Soul Regeneration Limited | Health & social care | 2026 |
| Skin by SL Ltd | Other services | 2024 |
| Smarties Holdings Limited | Real estate | 2025 |
| Smith Pickup Holdings Ltd | Real estate | 2020 |
| Smoogle Games Ltd | Information & communication | 2026 |
| Sneasby Allen LLP | | 2023 |
| Snugglebums Day Nursery Limited | Health & social care | 2014 |
| Snuggles Day Nursery (Denbigh) Limited | Education | 2019 |
| Sodhium Asset Management Limited | Real estate | 2019 |
| Sodhium Management Consulting Limited | Professional & scientific | 2015 |
| Soil Horizons Limited | Professional & scientific | 2011 |
| Solutas Legacy Ltd | Professional & scientific | 2025 |