| Speed Marc Ltd | Transport & logistics | 2014 |
| Speedex Recovery Ltd | Transport & logistics | 2024 |
| Speedy Auto Hub Ltd | Wholesale & retail | 2011 |
| Speedy Hawk Logistic Ltd | Transport & logistics | 2025 |
| Speedy Movers Ltd | Transport & logistics | 2024 |
| Speedy Savings Ltd | Wholesale & retail | 2024 |
| Speedy Transport Solutions Ltd | Transport & logistics | 2022 |
| Speedy Yankee Ltd | Transport & logistics | 2015 |
| Spencer Medical Group Ltd | Health & social care | 2026 |
| Spendeasy Ltd | Wholesale & retail | 2025 |
| SPI Finance Limited | Financial services | 2024 |
| Spice Box Luton Catering Ltd | Hospitality | 2025 |
| Spice Builders UK Ltd | Construction | 2023 |
| Spice Garden Indian Cuisine Ltd | Hospitality | 2015 |
| Spice Garden Romford Ltd | Hospitality | 2017 |
| Spice HUT (Luton) Limited | Hospitality | 2004 |
| Spice Merchants ST Albans Limited | Hospitality | 2006 |
| Spice of Caddington Ltd | Hospitality | 2026 |
| Spice Quay Developments Limited | Construction | 2006 |
| Spice Rack Harpenden Ltd | Hospitality | 2015 |
| Spice Rack Wellington Ltd | Hospitality | 2024 |
| Spice Route JM Ltd | Hospitality | 2026 |
| Spice Time Ltd | Hospitality | 2020 |
| Spicelounge Herts Ltd | Hospitality | 2018 |
| Spicy Chicken (Luton) Limited | Hospitality | 2015 |
| Spicy Fish & Chips & Desserts Ltd | Hospitality | 2023 |
| Spicy Haven Limited | Hospitality | 2025 |
| Spicy in Hub Limited | Hospitality | 2025 |
| Spicy Karahi Luton Ltd | Hospitality | 2019 |
| Spicy Rose Ltd | Hospitality | 2023 |
| Spin Rentals Ltd | Administrative & support | 2018 |
| Spiritual Atlas Limited | Information & communication | 2025 |
| Spirulina Trading Limited | Hospitality | 2019 |
| Spizi Security Ltd. | Professional & scientific | 2022 |
| Split Edit Limited | Information & communication | 2023 |
| Spooint Limited | Financial services | 2026 |
| Sporting Wholesale Holdings Limited | Financial services | 2019 |
| Sporting Wholesale Ltd | Wholesale & retail | 2011 |
| Sports Impo Limited | Arts & recreation | 2024 |
| Sports Inside Limited | Wholesale & retail | 2014 |
| Sports Insight Ltd | Information & communication | 2025 |
| Sports Management Services Limited | Arts & recreation | 2026 |
| Sports Wear Hub Ltd | Wholesale & retail | 2025 |
| Sportsmart Ltd | Wholesale & retail | 2026 |
| Spot Advertising Limited | Manufacturing | 2018 |
| Spot Training | Education | 2022 |
| Spotless Move Limited | Wholesale & retail | 2025 |
| Spotlight Games Ltd | Wholesale & retail | 2025 |
| Spoton Glazing Ltd | Construction | 2026 |
| SPP Limited | Real estate | 2026 |
| SPP Management Ltd | Real estate | 2023 |
| Spread Your Wings Ltd | Hospitality | 2023 |
| Spring and Co Solicitors Ltd | Professional & scientific | 2013 |
| Spring Bleau Dementia Cafe CIC | Health & social care | 2025 |
| Spring Consultancy Services Ltd | Professional & scientific | 2023 |
| Spring Gate Real Estate Ltd | Real estate | 2018 |
| Spring Stone Ltd | Construction | 2025 |
| Sprouts Social Ltd | Professional & scientific | 2024 |
| SPS Building Construction Limited | Construction | 2024 |
| SPS Properties Luton Ltd | Real estate | 2013 |
| SPS Residential Ltd | Real estate | 2021 |
| SPS Services (Luton) Ltd | Construction | 2017 |
| Spud Boss Ltd | Hospitality | 2024 |
| Spud Experts Ltd | Hospitality | 2024 |
| Spud MAD Ltd | Hospitality | 2024 |
| Spud Squad UK Limited | Hospitality | 2024 |
| Spud Therapy Limited | Hospitality | 2024 |
| SPV Property Development Ltd | Real estate | 2025 |
| Sp’S Kitchen Ltd | Hospitality | 2023 |
| Squash the Beef Limited | Hospitality | 2024 |
| SR ALL Wood & Building Work Ltd | Construction | 2025 |
| SR Capital Property Ltd | Real estate | 2023 |
| SR Coachconsulting Ltd | Professional & scientific | 2025 |
| SR Distribution Limited | Manufacturing | 2023 |
| SR Express Ltd | Transport & logistics | 2026 |
| SR Food&Wine Ltd | Wholesale & retail | 2022 |
| SR Lineage Property Holdings Ltd | Real estate | 2026 |
| SR Ophthalmic Ltd | Health & social care | 2021 |
| SR Refinish Limited | Manufacturing | 2023 |
| Sr&A Property's Ltd | Real estate | 2022 |
| SR3 Ltd | Transport & logistics | 2026 |
| SR7 Transport Ltd | Transport & logistics | 2026 |
| SRA Assets Limited | Administrative & support | 2026 |
| SRA Engineering Ltd | Other services | 2018 |
| SRA IT Services Limited | Information & communication | 2025 |
| SRA Star Ltd | Construction | 2018 |
| SRB Drylining Ltd | Construction | 2025 |
| SRI Badrakali Ltd | Public administration | 2025 |
| SRI Holdings Ltd | Financial services | 2016 |
| SRI Ramakrishna International UK Ltd | Health & social care | 2025 |
| SRI Siva Studios Ltd | Information & communication | 2025 |
| SRI Techno Front Solutions Ltd | Information & communication | 2025 |
| Srih Ltd | Construction | 2025 |
| Sriharsha Limited | Information & communication | 2025 |
| Srijo Ltd | Real estate | 2025 |
| Sriluxe Limited | Wholesale & retail | 2021 |
| SRK Services Ltd | Information & communication | 2025 |
| Srkm Consulting Limited | Professional & scientific | 2016 |
| SRP Property Consultancy Limited | Professional & scientific | 2021 |
| SRR Consultancy Ltd | Other services | 2022 |