| Sales Geek Liverpool Ltd | Professional & scientific | 2022 |
| SALES1 Ltd | Administrative & support | 2023 |
| Salex Design Services Ltd | Information & communication | 2008 |
| Salex Properties (NW) Ltd | Real estate | 2020 |
| Salford Lounge Ltd | Real estate | 2024 |
| Sali-T Limited | Hospitality | 2020 |
| Salient Collective Ltd | Administrative & support | 2025 |
| Salis Care C.I.C. | Health & social care | 2020 |
| Salis Children's Service Ltd | Health & social care | 2025 |
| Salisbury Housing Partnership Limited | Real estate | 2018 |
| Salisstudio Ltd | Professional & scientific | 2025 |
| Salix House Limited | Information & communication | 2022 |
| Sally Louise Fitness Ltd | Arts & recreation | 2019 |
| Sallystan Ltd | Wholesale & retail | 2025 |
| Salmella Ltd | Real estate | 2026 |
| Salmins Music Limited | Arts & recreation | 2011 |
| Salon 660 Beauty Ltd | Other services | 2022 |
| Salon 660 Hair Ltd | Other services | 2022 |
| Salon 92 Ltd | Other services | 2024 |
| Salon Bond Ltd | Extraterritorial | 2019 |
| Salon Delphine Ltd | Other services | 2026 |
| Salon Fittings Limited | Construction | 2019 |
| Salon Istanbul Ltd | Other services | 2018 |
| SALON26 Collective Limited | Other services | 2025 |
| Salonica-Ortho Ltd | Health & social care | 2013 |
| Salons Direct Holdings Limited | Administrative & support | 2021 |
| Salons Direct Properties Holdings Limited | Administrative & support | 2021 |
| Salons Direct Properties Limited | Real estate | 2021 |
| Salpricate Trading UK Limited | Construction | 2017 |
| Salsa Barber Ltd | Other services | 2024 |
| Salsc Consulting Ltd | Information & communication | 2023 |
| Salt & Pepper Dpgs Ltd | Hospitality | 2025 |
| Salt & Vinegar Chippy Limited | Hospitality | 2024 |
| Salt (Merseyside) Limited | Education | 2006 |
| Salt + Pepper Shack Ltd | Hospitality | 2025 |
| Salt Insurance Services Limited | Financial services | 2008 |
| Salter Construction Ltd | Construction | 2020 |
| Salter Joinery and Construction Ltd | Construction | 2025 |
| Saltings Holidays Limited | Real estate | 2022 |
| Saltra X1 (Salford) Management Limited | Households | 2013 |
| Saltra X2 (Salford) Management Limited | Households | 2015 |
| Salutation Bar and Cafe Limited | Hospitality | 2025 |
| Salvation (Birkenhead) CIC | Health & social care | 2026 |
| Salvay Limited | Health & social care | 2019 |
| Salvera Services Ltd | Administrative & support | 2016 |
| Salvesen (UK) Limited | Professional & scientific | 1993 |
| Salvesen Properties Limited | Real estate | 2011 |
| Salvus Electrical, Fire and Security Ltd | Construction | 2019 |
| SAM 1 Store Ltd | Wholesale & retail | 2026 |
| SAM 16 Limited | Wholesale & retail | 2017 |
| SAM Barber Wirral Ltd | Other services | 2021 |
| SAM City for General Trading Ltd | Wholesale & retail | 2024 |
| SAM Enterprisess Ltd | Wholesale & retail | 2020 |
| SAM Flynn Racing Ltd | Arts & recreation | 2022 |
| SAM Gibson SET Lighting Limited | Information & communication | 2019 |
| SAM Givnan Properties Ltd | Financial services | 2024 |
| SAM Hurst Developments Limited | Construction | 2025 |
| SAM Mccarthy Limited | Administrative & support | 2019 |
| SAM Vicker Management Ltd | Professional & scientific | 2024 |
| Sam's Courier and Removal Service Limited | Transport & logistics | 2025 |
| Sam's Garage Liverpool Ltd | Wholesale & retail | 2026 |
| Sam's Retail Group Ltd | Wholesale & retail | 2023 |
| Sam's Retail Shop Ltd | Wholesale & retail | 2025 |
| Sama United Ltd | Wholesale & retail | 2025 |
| Samac by SAM Ltd | Manufacturing | 2026 |
| Saman Ltd | Wholesale & retail | 2017 |
| Samantha Flynn Ltd | Administrative & support | 2017 |
| Samantha Greene Consulting Limited | Professional & scientific | 2016 |
| Samarie Centre CIC | Health & social care | 2022 |
| Sambit Limited | Information & communication | 2026 |
| Samcon Limited | Real estate | 2025 |
| Same Day Express Deliveries Ltd | Other services | 2018 |
| Same Day Smile Limited | Other services | 2019 |
| Same Logistics Ltd | Transport & logistics | 2025 |
| Same Tram Consulting Limited | Information & communication | 2015 |
| Sameday Distribution Network Limited | Transport & logistics | 2020 |
| Samepage Group Limited | Information & communication | 2015 |
| Samet Jiyan Limited | Professional & scientific | 2020 |
| Samford Holdings Ltd | Professional & scientific | 2019 |
| Samina Traders Ltd | Wholesale & retail | 2022 |
| Samkara Limited | Hospitality | 2024 |
| Sammed Cleaners Ltd | Administrative & support | 2023 |
| Sammercy Limited | Health & social care | 2015 |
| Sammi D Ltd | Wholesale & retail | 2016 |
| Sammy Babs Ltd | Transport & logistics | 2024 |
| Sammy Tech Services Ltd | Information & communication | 2025 |
| Samodrums Ltd | Administrative & support | 2025 |
| Sample Text Productions Ltd | Information & communication | 2026 |
| Sams Building and Groundworks Limited | Construction | 2019 |
| Sams Kitchen Express Ltd | Hospitality | 2025 |
| Sams Liverpool Limited | Hospitality | 2018 |
| Sams News Ltd | Wholesale & retail | 2018 |
| Samsara Cosmetics Studio Ltd | Other services | 2024 |
| Samson Group Limited | Administrative & support | 2002 |
| Samson Security Ltd | Administrative & support | 2000 |
| Samson Technical Services Ltd | Administrative & support | 2018 |
| Samsun Property Ltd | Real estate | 2021 |
| Samthejanner.Com Ltd | Manufacturing | 2025 |
| Samuel Beilin and Partners Limited | Professional & scientific | 2013 |
| Samuel Construction Ltd | Construction | 2002 |