| Spotless Cleaning Services Lincoln Limited | Administrative & support | 2018 |
| Spotless Cleaning Solutions and Services Ltd | Administrative & support | 2025 |
| Spotlight Dance Studio Limited | Arts & recreation | 2019 |
| SPR Consultants Limited | Information & communication | 2004 |
| SPR Consults Ltd | Professional & scientific | 2025 |
| Sprayer Spares Limited | Manufacturing | 2004 |
| Sprezzatura Clothing Ltd | Manufacturing | 2025 |
| Spring (Market Rasen) Limited | Professional & scientific | 2000 |
| Spring Beach Limited | Arts & recreation | 2017 |
| Spring Farm Properties and Agriculture Limited | Real estate | 1999 |
| Spring Hill House (Lincoln) Limited | Health & social care | 2026 |
| Spring Homes (Lincoln) Limited | Real estate | 2018 |
| Spring Steps Gymnastics Club Ltd | Arts & recreation | 2025 |
| Spring Sunrise Limited | Real estate | 2024 |
| Springbok Computers Ltd | Wholesale & retail | 2019 |
| Springline Farming Company Limited | Agriculture & fishing | 2008 |
| Springthorpe Developments LLP | | 2021 |
| Springtime Consultancy Ltd | Professional & scientific | 2026 |
| Springwell Consultants Limited | Professional & scientific | 2025 |
| Sprinkle Berry Limited | Hospitality | 2022 |
| SPS Builders Ltd | Construction | 2026 |
| Spsc (UK) Ltd | Construction | 2013 |
| Spud Stop Lincoln Limited | Hospitality | 2025 |
| Spur World Ltd | Arts & recreation | 2020 |
| Squirrels Nest Soft Play Lounge Limited | Health & social care | 2025 |
| Squirrels Property Maintenance Ltd | Construction | 2019 |
| SR Comms Ltd | Professional & scientific | 2022 |
| SR Sparks Ltd | Construction | 2026 |
| SRA Architecture Limited | Professional & scientific | 2005 |
| SRC UK Limited | Professional & scientific | 2019 |
| SRE Logistics Limited | Transport & logistics | 2026 |
| Sridh Surgery Limited | Health & social care | 2021 |
| SRN Estate Holding Limited | Financial services | 2025 |
| SRN Estate Limited | Real estate | 2017 |
| SRP Hire Solutions Ltd | Administrative & support | 2008 |
| SRT Innovative Business Ltd | Administrative & support | 2023 |
| SS Sparkle and Shine Ltd | Administrative & support | 2024 |
| SSG (LN) Limited | Hospitality | 2017 |
| SSH NO 2 Ltd | Financial services | 2024 |
| SSO Estates Ltd | Real estate | 2025 |
| SSO Homes Ltd | Real estate | 2025 |
| SSV Properties Limited | Real estate | 2019 |
| SSV Retail Limited | Wholesale & retail | 2014 |
| ST Botolphs Management Limited | Professional & scientific | 2026 |
| ST Francis Green Manco Ltd | Households | 2026 |
| ST Group Ltd | Professional & scientific | 2020 |
| ST Hugh Limited | Construction | 2013 |
| ST Johns Chapel Management Company Limited | Households | 2015 |
| ST Johns Travel Ltd | Administrative & support | 2007 |
| ST Joseph's Property Solutions Ltd | Construction | 2024 |
| ST Katherine's Cathedral Lincoln (TAC) Limited | Arts & recreation | 2019 |
| ST Martins Music Limited | Extraterritorial | 1994 |
| ST Nicholas House Management Company Ltd | Households | 2015 |
| ST Peter's Church Limited | Real estate | 2015 |
| ST Peters Court (Newton on Trent) Limited | Households | 2022 |
| ST. James Place North Hykeham Limited | Administrative & support | 2007 |
| ST. Nicholas Court (Lincoln) Limited | Administrative & support | 1977 |
| ST. Nicholas Meats Limited | Wholesale & retail | 2013 |
| St.Vincent Civils Limited | Extraterritorial | 2015 |
| Staar Player Ltd | Arts & recreation | 2024 |
| Stables Wood Farm Ltd | Hospitality | 2020 |
| Stabusgor Ltd | Wholesale & retail | 2026 |
| Stacey & SON Ltd | Wholesale & retail | 2023 |
| Staffordshire Associated Potters Ltd | Administrative & support | 2018 |
| Stage Eight Business Limited | Wholesale & retail | 2020 |
| Stage Eight Vapes Limited | Wholesale & retail | 2025 |
| Stagesoft Ltd | Information & communication | 2021 |
| Stairchangers Ltd | Construction | 2025 |
| Stairlift Spares Limited | Administrative & support | 2003 |
| Stamar Electronics Limited | Manufacturing | 2015 |
| Stanbridge Associates Ltd. | Professional & scientific | 1978 |
| Standby Standby Ltd | Other services | 2025 |
| Stanevisinivan Ltd | Hospitality | 2025 |
| Stanford Property Finance Ltd | Financial services | 2019 |
| Stanhope House Properties Limited | Financial services | 2026 |
| Stanhope UK Ltd | Construction | 2009 |
| Stankevic Joinery Ltd | Construction | 2025 |
| Stanley Property Ltd | Real estate | 2020 |
| Stanney Plastering Limited | Construction | 2015 |
| Star & Garter PUB Limited | Hospitality | 2025 |
| Star and Garter (Metheringham) Limited | Hospitality | 2016 |
| Star Energy Group PLC | Mining & quarrying | 2003 |
| Star Energy Limited | Mining & quarrying | 1999 |
| Star Energy Weald Basin Limited | Mining & quarrying | 2007 |
| Star Trust (East Midlands) Limited | Health & social care | 2013 |
| Starbound Labs Ltd | Professional & scientific | 2025 |
| Starglaze Windows and Conservatories Limited | Manufacturing | 1992 |
| Stark Contracts Ltd | Administrative & support | 2024 |
| Starkey & Brown (Lincoln Lettings) Limited | Real estate | 2014 |
| Starkey & Brown Land & New Homes Ltd | Real estate | 2011 |
| Starkey & Brown Lettings Limited | Real estate | 2008 |
| Starkey & Brown Limited | Real estate | 2007 |
| Starkey Investments Limited | Real estate | 2013 |
| Stars Sphere Limited | Information & communication | 2025 |
| Stately Limited | Other services | 2019 |
| Statera Aesthetics Limited | Health & social care | 2020 |
| Static Caravans for Sale Ltd | Wholesale & retail | 2025 |
| Static Security Services Limited | Administrative & support | 1994 |
| Station Road Steam Limited | Manufacturing | 2002 |
| Station View Properties Limited | Real estate | 2026 |