| Quicklink Transport Ltd | Transport & logistics | 2019 |
| Quickthorn Properties Ltd | Real estate | 2024 |
| R V Tech Limited | Health & social care | 2018 |
| R&D Energy Controls Ltd | Professional & scientific | 2022 |
| R. and E. Bamford Limited | Manufacturing | 1986 |
| R.B Electrical (NW) Limited | Construction | 2021 |
| R1H Ltd | Construction | 2024 |
| Rachael Marie Limited | Wholesale & retail | 2017 |
| Rachel Burns Hair Ltd | Other services | 2022 |
| RAD Decals Limited | Professional & scientific | 2017 |
| Radioaid Ltd | Education | 2015 |
| RAE Weaver People & Health Consulting Ltd | Professional & scientific | 2026 |
| Railadvent Limited | Information & communication | 2021 |
| Ramoge Cosmetics Ltd | Wholesale & retail | 2021 |
| Rasburn Stage Technologies Ltd | Arts & recreation | 2023 |
| RAY Pattison Limited | Construction | 2005 |
| RDM Networks Ltd | Manufacturing | 2023 |
| Reachout ASC Ltd | Administrative & support | 2020 |
| Read P Limited | Wholesale & retail | 2026 |
| Ready Roof Limited | Construction | 2020 |
| Readyplant Limited | Administrative & support | 1984 |
| Realhomey Ltd | Real estate | 2024 |
| Rectory Farm (Croston) Management Company Limited | Households | 2014 |
| Recycled WAX Ltd | Manufacturing | 2026 |
| Red Badger Ltd | Professional & scientific | 2023 |
| Red Frog Photography Limited | Professional & scientific | 2022 |
| Red Hair(North West)Company Limited | Other services | 2010 |
| Red Rose Funeral Support Limited | Other services | 2019 |
| Red Rose Rentals Limited | Real estate | 2015 |
| Redemption Drinks Company Limited | Wholesale & retail | 2020 |
| Redemption Tattoos Limited | Arts & recreation | 2017 |
| Redfearn Marketing Ltd | Professional & scientific | 2025 |
| Redrock Group Ltd | Manufacturing | 2025 |
| Regenerage | Wholesale & retail | 2009 |
| Regent Bespoke Furniture Ltd | Transport & logistics | 2022 |
| Regent Sales Ltd | Wholesale & retail | 2020 |
| Religion Tattoo Studio Limited | Arts & recreation | 2019 |
| Renewable Energy Project Services Ltd | Professional & scientific | 2026 |
| Renley Homes Ltd | Construction | 2020 |
| Resource Worldwide Ltd | Professional & scientific | 2019 |
| Retro Point Holdings Ltd | Wholesale & retail | 2025 |
| Retro Revivals House Clearances Ltd | Water & waste | 2023 |
| Reuben Santer Limited | Professional & scientific | 2020 |
| Revelation Tattoo Studio Limited | Arts & recreation | 2019 |
| Revival Tattoos Limited | Arts & recreation | 2017 |
| Revoraautocare Ltd | Wholesale & retail | 2026 |
| RF Invest Group Ltd | Households | 2024 |
| Rhino Juice Limited | Wholesale & retail | 2013 |
| Ribble Motor Homes Ltd | Wholesale & retail | 2016 |
| Ribble Motorhome Rentals Ltd | Other services | 2023 |
| Rice of Punjab (India) Ltd | Other services | 2017 |
| Richard James Rentals Ltd | Real estate | 2024 |
| Rideable Ltd | Extraterritorial | 2025 |
| Ridgeline Conversions Ltd | Manufacturing | 2025 |
| Right Choice Conservatories (Chorley) Limited | Households | 2007 |
| Right Choice Design & Build Ltd | Construction | 2025 |
| Right Choice North West Ltd | Construction | 2022 |
| Righton Insulation Services Holdings Limited | Construction | 2009 |
| Rimmer Higson Limited | Professional & scientific | 2006 |
| Rinus a Limited | Real estate | 2009 |
| RJD Property Maintenance Ltd | Households | 2023 |
| RK Builders (Lancs) Ltd | Construction | 2013 |
| RLH Inspection Services Limited | Mining & quarrying | 2011 |
| RLS Energy Solutions Ltd | Construction | 2020 |
| RMC Property Lets Ltd | Real estate | 2025 |
| RMN Group Limited | Administrative & support | 2018 |
| RND Electrical Northwest Limited | Construction | 2018 |
| Roaches Group Ltd | Financial services | 2026 |
| Road 2 Home Ltd | Wholesale & retail | 2022 |
| Roadpave Recycling Limited | Manufacturing | 2015 |
| Robert Brooks Brickwork Ltd | Construction | 2018 |
| Robin Hood Mawdesley Management Company Limited | Households | 2026 |
| Robinson Medical Limited | Health & social care | 2022 |
| Robson Consulting Limited | Information & communication | 2014 |
| Rodi Cleaning Services Ltd | Administrative & support | 2022 |
| Rodrigue Landu Solicitor Ltd | Professional & scientific | 2022 |
| Romney Chrome Ltd | Wholesale & retail | 2025 |
| Room in Town Ltd | Real estate | 2020 |
| Roscow Mechanical Limited | Manufacturing | 2014 |
| Rose Refreshed Ltd | Hospitality | 2026 |
| Rosewood Architectural Services Ltd | Professional & scientific | 2012 |
| Royden Structures Limited | Manufacturing | 2010 |
| RSC Designs Ltd | Arts & recreation | 2022 |
| RSN NW Transport Ltd | Transport & logistics | 2021 |
| RT Productions Ltd | Information & communication | 2017 |
| RTG Automotive Limited | Wholesale & retail | 2013 |
| Rubber Technologies Ltd | Financial services | 2014 |
| Rudra Cosmetics Ltd | Wholesale & retail | 2024 |
| Rudra Properties MANCHESTER09 Limited | Real estate | 2023 |
| Rudra Wilmslow Ltd | Hospitality | 2023 |
| Rufford PRE School Ltd | Education | 2020 |
| Rushby’S Therapies Limited | Health & social care | 2026 |
| Ruskin Melton Ltd | Wholesale & retail | 2025 |
| Russell James Lettings Ltd | Real estate | 2026 |
| Russell Watkinson Landscapes Limited | Administrative & support | 2023 |
| Rust to Resto Limited | Wholesale & retail | 2022 |
| Ruthney I Ltd | Administrative & support | 2026 |
| Ruttle Construction Limited | Construction | 2005 |
| Ruttle Investments Ltd | Real estate | 2015 |
| Ruttle Properties Limited | Real estate | 1989 |