| Subsea Fluids Limited | Manufacturing | 2014 |
| Sudha UNI Limited | Wholesale & retail | 2019 |
| Suits U Fitness Ltd | Arts & recreation | 2018 |
| Summit Bespoke Joinery & Interiors Ltd | Construction | 2025 |
| Sunala Limited | Administrative & support | 1998 |
| Sunbathe Sunbed Hire Ltd | Construction | 2014 |
| Sunshine Retreats Limited | Other services | 2016 |
| Super Fast Car Rentals Ltd | Administrative & support | 2022 |
| Superspeed Engineering Solutions Limited | Professional & scientific | 2007 |
| Supplies Corp Ltd | Wholesale & retail | 2022 |
| Sure Electrical Limited | Manufacturing | 2023 |
| Sure Electrical Wholesale Ltd | Construction | 2018 |
| Sure Group Services Ltd | Financial services | 2025 |
| Svsa Limited | Real estate | 2019 |
| SW Projects Building Contractor Ltd | Construction | 2018 |
| Swan Beauty Ltd | Wholesale & retail | 2019 |
| Swank Clean Ltd | Administrative & support | 2025 |
| SWD Tiling Ltd | Construction | 2025 |
| Sweet Chemistry Ltd | Wholesale & retail | 2020 |
| Swift Roofing & Building Ltd | Construction | 2025 |
| Swimbox Limited | Education | 2021 |
| SX Signs Ltd | Manufacturing | 2014 |
| Synergy Lettings Ltd | Real estate | 2019 |
| Synergy Sign and Print Ltd | Professional & scientific | 2011 |
| T Dube Ltd | Health & social care | 2022 |
| T K Grills Ltd | Hospitality | 2025 |
| T&A Engineering Ltd | Professional & scientific | 2022 |
| T&M Property Partners Ltd | Real estate | 2024 |
| T&M UK Group Limited | Financial services | 2022 |
| T&T Rentals Ltd | Real estate | 2026 |
| T&T Sargeant Bakers Ltd | Manufacturing | 2024 |
| T.S.M. (Clitheroe) Limited | Manufacturing | 2016 |
| TA Commercial Limited | Professional & scientific | 2023 |
| Tackle Taxi Ltd | Transport & logistics | 2025 |
| Tadeu Transport Ltd | Transport & logistics | 2026 |
| Tailored Support Limited | Health & social care | 2023 |
| Tamar Stores Limited | Wholesale & retail | 2012 |
| Tandy Electronics Ltd | Wholesale & retail | 2026 |
| Tank Cafe Limited | Extraterritorial | 2007 |
| Tank Coffee Limited | Wholesale & retail | 2007 |
| Tank Group Limited | Extraterritorial | 2007 |
| Tann Westlake Ltd. | Administrative & support | 2002 |
| Tannahill Reay Visual Communications Limited | Administrative & support | 1994 |
| Tanom Advertising Ltd | Information & communication | 2025 |
| TAP Interiors Limited | Construction | 2011 |
| Tashamel Healthcare Services Ltd | Health & social care | 2018 |
| Taylor-Made Mortgages Limited | Financial services | 2003 |
| Tbdc Properties Ltd | Real estate | 2025 |
| TD Wealth Management Limited | Financial services | 2017 |
| Teezy Ltd | Wholesale & retail | 2023 |
| Telecast Limited | Information & communication | 2004 |
| Terry Marie Needham Ltd | Extraterritorial | 2024 |
| Terry Marie Pemberton Limited | Extraterritorial | 2024 |
| Tespec Ltd | Information & communication | 2025 |
| Textures Hair Salon Limited | Other services | 2004 |
| Tgcs Property Maintenance Ltd | Other services | 2021 |
| Tgea Leigh Ltd | Real estate | 2024 |
| That Burger Place (Walkden) Ltd | Hospitality | 2022 |
| THE Avenue Private Day Care Limited | Health & social care | 2018 |
| THE Baby Room at Spinners CIC | Education | 2022 |
| THE Barber Shop at Plus Two Limited | Other services | 2011 |
| THE BD Kebab Limited | Wholesale & retail | 2024 |
| THE Beeches 148 Ltd | Households | 2018 |
| THE Beeches Early Years Consultancy Limited | Health & social care | 2016 |
| THE Bespoke Balloon Co Ltd | Wholesale & retail | 2017 |
| THE Blue Artisan Ltd | Administrative & support | 2013 |
| THE Brokerage Property Ltd | Construction | 2026 |
| THE BUS Yard Ltd | Hospitality | 2021 |
| THE Clinyc Limited | Other services | 2018 |
| THE Coal Room Ltd | Hospitality | 2018 |
| THE Couples Retreat Limited | Other services | 2026 |
| THE Crispy Waffle Ltd | Hospitality | 2025 |
| THE Dog Wash Station Ltd | Manufacturing | 2024 |
| THE Harmony, Unity & Belonging C.I.C. | Health & social care | 2016 |
| THE Hawthorns Management Company (Edenfield) Limited | Real estate | 2023 |
| THE Hospitality HUT Ltd | Professional & scientific | 2020 |
| THE Jewellery Emporium Ltd | Wholesale & retail | 2009 |
| THE Kick Vault Limited | Arts & recreation | 2025 |
| THE KIR Hair Company Ltd | Wholesale & retail | 2015 |
| THE Leigh Bakery Ltd | Hospitality | 2026 |
| THE Leigh Miners Welfare Institute and Recreation Ground Social Club Limited | Hospitality | 1992 |
| THE LEV Group Ltd | Financial services | 2018 |
| THE Light Yard Ltd | Wholesale & retail | 2015 |
| THE Little Carpet Shop Leigh Ltd | Wholesale & retail | 2024 |
| THE Lowton Creative Company Ltd | Manufacturing | 2023 |
| THE M & M Apartments and Logistics Ltd | Real estate | 2026 |
| THE Mahid Group Ltd | Wholesale & retail | 2026 |
| THE Maine OFF Licence Limited | Wholesale & retail | 2020 |
| THE Maud Saga Ltd. | Information & communication | 2023 |
| THE Men's Collective Ltd | Wholesale & retail | 2025 |
| THE Mindset Movement Limited | Information & communication | 2016 |
| THE Northern Decorative Glass Company Ltd. | Manufacturing | 2000 |
| THE Old Stables (Leigh) Management Company Limited | Real estate | 2005 |
| THE Printed PEN Company Limited | Wholesale & retail | 2009 |
| THE Pro Landscapers Ltd | Other services | 2019 |
| THE Property Developer Ltd | Construction | 2023 |
| THE Real Bakery Limited | Hospitality | 2022 |
| THE Resin Guyss Ltd | Construction | 2025 |
| THE Rodan Group Limited | Professional & scientific | 2014 |
| THE Sales Progression Company Ltd | Real estate | 2026 |