| Studio AXO Ltd | Professional & scientific | 2024 |
| Studio Brick Consultancy Ltd | Wholesale & retail | 2020 |
| Studio Burns Media Ltd | Information & communication | 2021 |
| Studio Digital Leicester Ltd | Professional & scientific | 2010 |
| Studio East Ltd | Wholesale & retail | 2020 |
| Studio Events Ltd | Arts & recreation | 2025 |
| Studio Fifty Five Ltd | Information & communication | 2018 |
| Studio Figura Leicester Ltd | Other services | 2023 |
| Studio LET Ltd | Real estate | 2025 |
| Studio Lifestyle Ltd | Arts & recreation | 2025 |
| Studio NG Ltd | Professional & scientific | 2019 |
| Studio One Ltd | Manufacturing | 2005 |
| Studio Padel Leicester Ltd | Arts & recreation | 2025 |
| Studio Refined Ltd | Manufacturing | 2024 |
| Studio RN Limited | Real estate | 2020 |
| Studio Rokit Limited | Information & communication | 2012 |
| Studio Sunnie Ltd | Professional & scientific | 2024 |
| Studio Twenty Barbers Ltd | Other services | 2025 |
| Studio Z (Leicester) Limited | Other services | 2025 |
| Studio Z Dance Ltd | Arts & recreation | 2024 |
| STUDIO-82-UK Ltd | Wholesale & retail | 2022 |
| STUDIO07 Limited | Hospitality | 2017 |
| STUDIO31 Ltd | Professional & scientific | 2013 |
| Studioname Leicester CIC | Arts & recreation | 2017 |
| Studioname Limited | Arts & recreation | 2016 |
| Studious Living Limited | Real estate | 2018 |
| Studiquo Limited | Education | 2025 |
| Study and Work Abroad Recruitment Ltd | Administrative & support | 2019 |
| Study for a Future Limited | Education | 2024 |
| Study Runners Limited | Wholesale & retail | 2022 |
| Studyfy Ltd | Education | 2023 |
| Stump&Co Limited | Arts & recreation | 2023 |
| Sturford Transport Ltd | Transport & logistics | 2014 |
| Sturgess & Thompson Limited | Wholesale & retail | 1965 |
| Sturgess Hutchinson (Leicester) Limited | Professional & scientific | 2011 |
| Sturgess Hutchinson Limited | Professional & scientific | 2012 |
| Sturgess Investments Limited | Financial services | 2024 |
| Sturgess Newton Baker LLP | | 2012 |
| Sturgess Properties Group Limited | Real estate | 2025 |
| Sturgess Properties Holdings Limited | Real estate | 2025 |
| Sturgess Realisations Limited | Financial services | 2025 |
| Sturgess Subco Limited | Real estate | 2025 |
| Sturgess Trading Group Limited | Financial services | 2025 |
| Sturgis Shattock and Partners LLP | | 2004 |
| Sturgis Snow and Astill LLP | | 2010 |
| Stuston Ltd | Transport & logistics | 2015 |
| Style (UK) Limited | Professional & scientific | 1991 |
| Style Furnishing Leicester Ltd | Wholesale & retail | 2017 |
| Style Properties Limited | Real estate | 2021 |
| Style Revolver Limited | Real estate | 2019 |
| Style Synergy (Leicester) Ltd | Manufacturing | 2026 |
| Styled Hairdressing Ltd | Other services | 2026 |
| Stylehaus Group Ltd | Wholesale & retail | 2019 |
| Styleman Limited | Extraterritorial | 1991 |
| Stylendsmile Ltd | Other services | 2025 |
| Stylerio Fashion Ltd | Wholesale & retail | 2024 |
| Stylex (UK) Limited | Wholesale & retail | 2003 |
| Stylish UK Fashion Limited | Manufacturing | 2025 |
| Stypek Ltd | Transport & logistics | 2013 |
| SU & NIN Thai Spa Ltd | Other services | 2010 |
| SU and Ninya Ltd | Health & social care | 2013 |
| SU Properties Group Ltd | Real estate | 2023 |
| Su&Shi Limited | Hospitality | 2023 |
| Suave Bambino Limited | Manufacturing | 2016 |
| SUB Zero Air CON Ltd | Wholesale & retail | 2019 |
| Subha Homes Ltd | Real estate | 2023 |
| Subha Limited | Health & social care | 2011 |
| Subhani Enterprise Ltd | Health & social care | 2025 |
| Sublimation Print UK Limited | Manufacturing | 2010 |
| Sublique Limited | Manufacturing | 2018 |
| Subsidence Monitoring Limited | Extraterritorial | 2007 |
| Subtle Blend Software Ltd | Information & communication | 2016 |
| Subz Autos Ltd | Wholesale & retail | 2023 |
| Succede Ltd | Professional & scientific | 2025 |
| Succedo Ltd | Wholesale & retail | 2022 |
| Success Cafe Ltd | Hospitality | 2024 |
| Success Recruitment Consultancy Limited | Administrative & support | 2022 |
| Success Seekers Ltd | Education | 2023 |
| Success Stone Limited | Professional & scientific | 2024 |
| Success Synergy Ltd | Education | 2024 |
| Successful GP Northeast Ltd | Health & social care | 2023 |
| Suchak Group Worldwide Ltd | Wholesale & retail | 2023 |
| Suchi Express Ltd | Transport & logistics | 2026 |
| Sudama Limited | Wholesale & retail | 2020 |
| Sudamose Limited | Health & social care | 2022 |
| Sudanese Darfur Association in Leicester Limited | Health & social care | 2016 |
| Sudera Care Associates Limited | Health & social care | 2004 |
| Sudera Minerals Ltd. | Extraterritorial | 2012 |
| Sudiri Ltd | Real estate | 2023 |
| Sudra Investments Limited | Real estate | 2025 |
| SUE Bridge Consulting Limited | Professional & scientific | 2014 |
| SUE Pryke Limited | Manufacturing | 2022 |
| SUE Rastall Ltd | Education | 2009 |
| SUE Young Cancer Support in Leicestershire and Rutland | Health & social care | 2007 |
| Suez Canal Barbers Ltd | Other services | 2023 |
| Suezcanal Freight Ltd | Transport & logistics | 2018 |
| Sufa Steelfixing Ltd | Construction | 2020 |
| Suffa Investments Ltd | Real estate | 2022 |
| Suffolk & Suffolk Limited | Financial services | 2024 |
| Suffolk Dance Property Ltd | Real estate | 2011 |