| Strategic Response Solutions Ltd | Education | 2026 |
| Strategic Risk Management (Asbestos) Limited | Professional & scientific | 2007 |
| Strategic Risk Management Limited | Professional & scientific | 2003 |
| Strategy Implementation Associates Limited | Professional & scientific | 2016 |
| Strategytech Ltd | Professional & scientific | 2018 |
| Stratera Energy Limited | Energy | 2025 |
| Stratford Retail Group Limited | Professional & scientific | 2018 |
| Stratford Retail Partners LLP | | 2018 |
| Strathmore College Limited | Education | 2001 |
| Stratolens Aviation Limited | Manufacturing | 2025 |
| Stratos Events Ltd | Administrative & support | 2026 |
| Stratrock Limited | Other services | 2023 |
| Stratton Assist Ltd | Construction | 2021 |
| Stratton Mills Ltd | Health & social care | 2015 |
| Stratton Mills Recruitment Ltd | Administrative & support | 2017 |
| Stratton Oakmont Fabrications Ltd | Manufacturing | 2019 |
| Stratton Oakmont Real Estate Limited | Real estate | 2022 |
| Stravion Construction Group Ltd | Construction | 2026 |
| Strawberry Fusion Limited | Administrative & support | 2000 |
| Strawberry Games Limited | Information & communication | 2014 |
| Strawberry Hill Rose Limited | Hospitality | 2023 |
| Streakline Ltd | Transport & logistics | 2018 |
| Streamline Guttering Limited | Construction | 2015 |
| Streamviral Ltd | Information & communication | 2020 |
| Street Fodder Limited | Wholesale & retail | 2021 |
| Street Food LAB Ltd | Hospitality | 2019 |
| Street News Ltd | Real estate | 2016 |
| Street Racers Direct Ltd | Wholesale & retail | 2018 |
| Street Taste Co Ltd | Wholesale & retail | 2019 |
| Street Taste Leicester Ltd | Hospitality | 2024 |
| Strela Holdings Limited | Financial services | 2024 |
| Strela Ltd | Construction | 2017 |
| Stress Free Support Ltd. | Health & social care | 2015 |
| Stressline Engineering Limited | Administrative & support | 2005 |
| Stressline Holdings Limited | Financial services | 1997 |
| Stretchit Elastic Limited | Manufacturing | 2000 |
| Stretton 2000 Limited | Arts & recreation | 2000 |
| Stretton Court Management (Leicester) Limited | Real estate | 2000 |
| Stretton FOX Ltd | Manufacturing | 2024 |
| Stretton FOX Technologies Ltd | Financial services | 2024 |
| Stretton IT Services Ltd | Information & communication | 2010 |
| Stretton Property Solutions Limited | Real estate | 2019 |
| Stretton Surveys Limited | Professional & scientific | 2024 |
| Strettons Holdings Limited | Financial services | 2026 |
| Strevens Vehicles Holdings Limited | Professional & scientific | 1992 |
| Strictly SME Ltd | Professional & scientific | 2025 |
| Stride Enterprises Ltd | Extraterritorial | 2014 |
| Stride Properties Ltd | Real estate | 2020 |
| Stride Resource Management Ltd | Administrative & support | 2019 |
| Strideup Ltd | Real estate | 2020 |
| STRIKE1 Contractors Limited | Administrative & support | 2017 |
| Strikepad Limited | Manufacturing | 2025 |
| Striker Europe Limited | Manufacturing | 2017 |
| Stringfellows Gentlemen’S Outfitters Ltd | Wholesale & retail | 2021 |
| Strip Weathers Limited | Education | 2022 |
| Striptweeze Ltd | Other services | 2009 |
| Strise Limited | Professional & scientific | 2019 |
| Strive Administration Support Ltd | Administrative & support | 2025 |
| Strive Learning & Interventions Ltd | Education | 2025 |
| Strive Properties Ltd | Real estate | 2013 |
| Strive Timber Limited | Construction | 2022 |
| Strive-Uk Ltd | Education | 2020 |
| Strobe 9 Ltd | Professional & scientific | 2005 |
| Strokham Innovations Ltd | Transport & logistics | 2015 |
| Strong Enterprises Limited | Professional & scientific | 2008 |
| Strong Fittings Limited | Manufacturing | 2018 |
| Strong Pilates (Leicester) Limited | Arts & recreation | 2023 |
| Strong Site Services Limited | Professional & scientific | 2019 |
| Stronghold Commercial Properties Limited | Construction | 2025 |
| Strongwood Solutions Limited | Construction | 2014 |
| Strouden Logistics Ltd | Transport & logistics | 2014 |
| Structskill Structural Services Ltd | Professional & scientific | 2016 |
| Structural Adhesives Limited | Manufacturing | 1989 |
| Strutchannels Direct.Com Ltd | Wholesale & retail | 2020 |
| STS Healthcare Ltd | Health & social care | 2017 |
| STS Precision Engineering Limited | Manufacturing | 2007 |
| STS Rail Ltd | Construction | 2017 |
| STS Van and MAN Hire Services Ltd | Administrative & support | 2017 |
| Sttch Ltd | Real estate | 2025 |
| STU Williamson Photography Limited | Professional & scientific | 2014 |
| Stuart Green and Associates Limited | Professional & scientific | 2020 |
| Stubart Driving Solutions Limited | Transport & logistics | 2017 |
| Student Events Ltd | Hospitality | 2022 |
| Student Express Accommodation Limited | Real estate | 2010 |
| Student Health Connect Ltd | Health & social care | 2025 |
| Student Properties Ltd | Real estate | 2024 |
| Student Recruitment and Cleaning Sloutions Ltd | Administrative & support | 2026 |
| Student Union Lettings Limited | Real estate | 2012 |
| Studentfirst Limited | Education | 2025 |
| Studio 101 Ltd | Manufacturing | 2018 |
| Studio 18 Ltd | Wholesale & retail | 2002 |
| Studio 56 Photography Limited | Professional & scientific | 2007 |
| Studio 59 Limited | Manufacturing | 2000 |
| Studio 62 Hair Design Limited | Other services | 2007 |
| Studio 79 Limited | Education | 2011 |
| Studio 79 Youth CIC | Arts & recreation | 2023 |
| Studio Altitude Holdings Ltd | Financial services | 2024 |
| Studio Altitude Ltd | Professional & scientific | 2021 |
| Studio Arcana Ltd | Professional & scientific | 2016 |
| Studio ATW Ltd | Professional & scientific | 2023 |