| SAC Medical Services Ltd | Health & social care | 2022 |
| SAC Restaurant Group Limited | Professional & scientific | 2026 |
| Sach P Capital Ltd. | Health & social care | 2019 |
| Sachania Bros Ltd | Wholesale & retail | 2013 |
| Sachdev Holdings Limited | Real estate | 2017 |
| Sachdev Properties Limited | Real estate | 2013 |
| Sachdev Real Estate Ltd | Real estate | 2025 |
| Sachdeva - Construction Ltd | Construction | 2022 |
| Sachin. V. Ltd | Other services | 2012 |
| Sachy Ltd | Professional & scientific | 2014 |
| Sackey's Limited | Administrative & support | 2017 |
| Sacoor Investments Ltd | Real estate | 2025 |
| Sacred Stays Ltd | Wholesale & retail | 2011 |
| Sacs Global Ltd | Wholesale & retail | 2024 |
| Sacursoftware Ltd | Information & communication | 2025 |
| Sada Punjab Limited | Wholesale & retail | 2025 |
| Sadguru OM Ltd | Information & communication | 2010 |
| Sadhra Construction Ltd | Construction | 2024 |
| Sadhra Styles Limited | Wholesale & retail | 2021 |
| Saeed Estates Ltd | Real estate | 2021 |
| Saeed Supermarket Leicester Ltd | Wholesale & retail | 2016 |
| SAF & Co Investments Ltd | Real estate | 2025 |
| SAF Accident Repair Centre Ltd | Wholesale & retail | 2024 |
| Safa SF Ltd | Real estate | 2025 |
| Safaa Investments Limited | Wholesale & retail | 2012 |
| Safanah UK Ltd | Administrative & support | 2014 |
| Safar Apparel Limited | Wholesale & retail | 2025 |
| Safca Ltd | Transport & logistics | 2021 |
| Safca Properties Ltd | Real estate | 2024 |
| Safco Investments Ltd | Real estate | 2021 |
| Safe & Quality Construction Ltd | Construction | 2025 |
| Safe and Happy Limited | Wholesale & retail | 2025 |
| Safe and Sound HSE Limited | Administrative & support | 2025 |
| Safe Construction (Leicester) Limited | Construction | 2018 |
| Safe Investment Management UK | Real estate | 2007 |
| Safe Lift Scaffolding Ltd | Construction | 2025 |
| Safe Play Ltd | Construction | 2022 |
| Safe Property Developments Ltd | Construction | 2015 |
| Safe Skips Waste Management Ltd | Water & waste | 2018 |
| Safecare Pharmaceuticals Limited | Wholesale & retail | 2020 |
| Safecare Pharmacy Limited | Professional & scientific | 2011 |
| Safechem Services Limited | Transport & logistics | 2019 |
| Safeer Perfume Ltd | Wholesale & retail | 2023 |
| Safeguard Systems Ltd | Administrative & support | 2013 |
| Safehaven Cyber Ltd | Professional & scientific | 2025 |
| Safely Investing Ltd | Financial services | 2021 |
| Safenest Properties Leicester Ltd | Real estate | 2026 |
| Safenest Removals Ltd | Transport & logistics | 2026 |
| Safer Hands (Medical) Ltd | Education | 2018 |
| Safer Spaces for ALL CIC | Education | 2025 |
| Safesell Ltd | Professional & scientific | 2019 |
| Safestep Platform Lifts Ltd | Manufacturing | 2026 |
| Safetofl Ltd | Professional & scientific | 2022 |
| Safety 4 Limited | Professional & scientific | 2007 |
| Safety and Maintenance Limited | Wholesale & retail | 2019 |
| Safety Fork Training Ltd | Education | 2022 |
| Safety Padding GB Ltd | Manufacturing | 2016 |
| Safety Systems Consultancy Ltd | Administrative & support | 2015 |
| Safeviation Limited | Information & communication | 2024 |
| Safewall Engineering Consultancy Ltd | Construction | 2026 |
| Safeworks Digital Ltd | Professional & scientific | 2026 |
| Safezone Protection Services Ltd | Administrative & support | 2023 |
| Saffire Investments Ltd | Real estate | 2026 |
| Saffron Assets Limited | Real estate | 2026 |
| Saffron Bar & Grill Ltd | Hospitality | 2023 |
| Saffron Barbers Ltd | Other services | 2024 |
| Saffron Car Wash Limited | Wholesale & retail | 2017 |
| Saffron Chicken Limited | Hospitality | 2019 |
| Saffron Events Limited | Information & communication | 2007 |
| Saffron Grocery Ltd | Wholesale & retail | 2024 |
| Saffron Indian Takeaway (Paddock Wood) Ltd | Hospitality | 2017 |
| Saffron Lane Chicken Ltd | Hospitality | 2024 |
| Saffron Lane Dental Ltd | Health & social care | 2013 |
| Saffron Lane Kebab Limited | Hospitality | 2023 |
| Saffron Lane Mini Market Ltd | Wholesale & retail | 2026 |
| Saffron Lane Neighbourhood Council | Education | 2017 |
| Saffron Leics Ltd | Wholesale & retail | 2024 |
| Saffron Pizza Ltd | Hospitality | 2022 |
| Saffron Sun Ltd | Hospitality | 2026 |
| Saffron Young Peoples Project Limited | Health & social care | 2001 |
| Safi Supported Living Community Interest Company | Health & social care | 2025 |
| Safia ALI Ltd | Health & social care | 2025 |
| Safiyah Pristine Homes Limited | Administrative & support | 2026 |
| Safla Estate Ltd | Real estate | 2024 |
| Safmo Holdings Ltd | Real estate | 2026 |
| Safora Beauty & Health Ltd | Wholesale & retail | 2025 |
| Safra Trading Ltd | Wholesale & retail | 2020 |
| Safsah Tyres Ltd | Wholesale & retail | 2022 |
| Safsta Enterprise Ltd | Health & social care | 2010 |
| Saftrade Limited | Wholesale & retail | 2021 |
| Safwah Tech Ltd | Information & communication | 2024 |
| Safwan Medical Limited | Health & social care | 2025 |
| Safys Limited | Wholesale & retail | 2023 |
| Saga Construction UK Limited | Construction | 2003 |
| Saga Events Ltd | Hospitality | 2024 |
| Saga INT Ltd | Administrative & support | 2016 |
| Saga of Cars Ltd | Wholesale & retail | 2025 |
| Sagal Transport Ltd | Transport & logistics | 2024 |
| Sagar Global Ltd | Wholesale & retail | 2024 |
| Sagar Optimizations Ltd | Real estate | 2018 |