| S. K. Jewellers Limited | Manufacturing | 2002 |
| S. N. Products Limited | Wholesale & retail | 2003 |
| S. Simm Limited | Manufacturing | 2002 |
| S. Z Fashions Ltd | Manufacturing | 2019 |
| S.A. Services Ltd | Construction | 1999 |
| S.A.M. Evolution Ltd | Real estate | 2021 |
| S.A.M.E Investments Ltd | Real estate | 2012 |
| S.A.N.A.M Properties Ltd | Real estate | 2022 |
| S.A.S. Decorating Services Limited | Construction | 2018 |
| S.Adatia Locum Services Ltd | Wholesale & retail | 2023 |
| S.F Opticals Ltd | Public administration | 2023 |
| S.F. Dean Ltd | Construction | 2003 |
| S.G.V.H. Construction Ltd | Construction | 2024 |
| S.H. Arts Limited | Administrative & support | 1999 |
| S.H.R.O.P. Holdings Limited | Financial services | 2025 |
| S.I.Opticals - Oadby Limited | Wholesale & retail | 2021 |
| S.I.Opticals-Narborough Limited | Wholesale & retail | 2022 |
| S.I.R. Fabrics (Imports & Exports) Limited | Manufacturing | 2012 |
| S.J Costello Property Ltd | Real estate | 2025 |
| S.J. Mears (Legal Services) Limited | Professional & scientific | 2023 |
| S.J. Messenger Haulage Limited | Transport & logistics | 2000 |
| S.K.Y.L.A.R Properties Ltd | Real estate | 2018 |
| S.M.S Easy Drying Solutions Ltd | Wholesale & retail | 2019 |
| S.N. Investmed Ltd | Real estate | 2021 |
| S.P. Kerr Ltd | Construction | 2005 |
| S.R.Woodward Ltd | Information & communication | 2017 |
| S.Rud Properties Limited | Households | 2023 |
| S.S.Heating Ltd | Construction | 2020 |
| S.Sohal Transportation Ltd | Transport & logistics | 2021 |
| S1 Enterprise Limited | Other services | 2022 |
| S117 Ltd | Financial services | 2023 |
| S2 Care Ltd | Health & social care | 2020 |
| S2 Enterprises Limited | Real estate | 2026 |
| S2 Images Ltd | Professional & scientific | 2014 |
| S24 Television Limited | Information & communication | 2026 |
| S2B Collective CIC | Other services | 2019 |
| S3 Builders Leicester Ltd | Construction | 2018 |
| S3 Care Ltd | Health & social care | 2018 |
| S3 Leicester Ltd | Hospitality | 2025 |
| S3S MA Ltd | Manufacturing | 2025 |
| S3Z Limited | Information & communication | 2016 |
| S4 Care Ltd | Health & social care | 2018 |
| S4 Leicester Ltd | Hospitality | 2026 |
| S41 Property Limited | Construction | 2022 |
| S4R Securities Limited | Administrative & support | 2021 |
| S4YON Property Limited | Construction | 2022 |
| S5 Care Ltd | Health & social care | 2019 |
| S5 Logistics Ltd | Wholesale & retail | 2025 |
| S50 Leicester Limited | Professional & scientific | 2014 |
| S55 Investments Ltd | Real estate | 2020 |
| S6 Care Ltd | Health & social care | 2023 |
| SA Compliance Ltd | Professional & scientific | 2026 |
| SA Driving Academy Limited | Education | 2025 |
| SA Edge Solutions Ltd | Professional & scientific | 2022 |
| SA Law Practice Ltd | Professional & scientific | 2019 |
| SA Same Day Ltd | Transport & logistics | 2018 |
| SA Supply Ltd | Wholesale & retail | 2025 |
| Sa-Ra Gift Shop Ltd | Wholesale & retail | 2019 |
| Saa'I Timepieces Ltd | Other services | 2015 |
| Saad Pizza Master Limited | Hospitality | 2023 |
| Saad Sayeed Ltd | Health & social care | 2011 |
| Saaduddin Fashion Ltd | Manufacturing | 2017 |
| Saaif Investments Limited | Real estate | 2017 |
| Saaiqa Accounting Services Ltd | Professional & scientific | 2024 |
| Saam Security Ltd | Administrative & support | 2021 |
| Saanvi Foods Limited | Hospitality | 2018 |
| Saar Transport Ltd | Transport & logistics | 2013 |
| Saarang Limited | Other services | 2011 |
| Saasa Homes Ltd | Health & social care | 2026 |
| Saaz Marketing Limited | Wholesale & retail | 2018 |
| Saazo Developments Ltd | Real estate | 2017 |
| Saazo LLP | | 2021 |
| SAB 1313 Ltd | Real estate | 2017 |
| SAB 1313 Properties Ltd | Real estate | 2011 |
| SAB International Limited | Wholesale & retail | 2006 |
| SAB Properties (Leics) Limited | Real estate | 2020 |
| SAB Windoors Ltd | Manufacturing | 2023 |
| Sab&S Ltd | Information & communication | 2012 |
| Saba Wholesalers Ltd | Wholesale & retail | 2018 |
| Sabat Holdings Ltd | Financial services | 2026 |
| Sabat Properties Ltd | Real estate | 2021 |
| Sabat Property Investments Limited | Real estate | 2001 |
| Sabbs Enterprise Ltd | Wholesale & retail | 2025 |
| Sabeha Gheewala Ltd | Health & social care | 2020 |
| Sabharwal Haulage Ltd | Transport & logistics | 2013 |
| Sabin Consultancy Limited | Information & communication | 2017 |
| Sable Lambert Garages Limited | Construction | 1965 |
| Saboor Khan Ltd | Wholesale & retail | 2025 |
| Sabr Care Ltd | Health & social care | 2024 |
| Sabr ENT Limited | Wholesale & retail | 2023 |
| Sabrah Solutions Ltd | Wholesale & retail | 2025 |
| Sabrida Ltd | Transport & logistics | 2017 |
| Sabriel Properties Limited | Professional & scientific | 2004 |
| Sabs Hair & Beauty Ltd | Other services | 2026 |
| Sabs Services Limited | Other services | 2019 |
| Sabsync Consulting Ltd | Information & communication | 2018 |
| Sabsync Ventures Limited | Real estate | 2020 |
| Saby Nails & Beauty Limited | Other services | 2016 |
| Sabz Investments Ltd | Real estate | 2021 |
| Sabz Online Ltd | Extraterritorial | 2013 |