| Talba Holdings Limited | Financial services | 2019 |
| Tallo Skincare Ltd | Manufacturing | 2026 |
| Tallow for Ltd | Manufacturing | 2025 |
| Taspa Sound & Light Engineering Limited | Manufacturing | 1987 |
| Taylors Heating Ltd | Construction | 2023 |
| Teachers Abroad Limited | Administrative & support | 2025 |
| Team Investments Ltd | Real estate | 2017 |
| Team Jolt Ltd | Administrative & support | 2022 |
| Technotex (UK) Limited | Extraterritorial | 1998 |
| Telic Solutions Limited | Professional & scientific | 2024 |
| TGM Fabrications Ltd | Manufacturing | 2024 |
| Thai Siam Ltd | Hospitality | 2019 |
| THE Alloy Hub Ltd | Wholesale & retail | 2013 |
| THE Business Psychologist Limited | Professional & scientific | 2024 |
| THE Capable Collective Ltd | Professional & scientific | 2026 |
| THE Cedar Park (Leek) Management Company Limited | Households | 2005 |
| THE Climbing Wall Company Limited | Manufacturing | 2016 |
| THE Cobblers (Leek) Limited | Hospitality | 2015 |
| THE College of Canine Professionals Ltd | Education | 2024 |
| THE Conclusion People Ltd | Professional & scientific | 2023 |
| THE Earl Grey Leek Ltd | Hospitality | 2014 |
| THE Hair Lounge (Leek) Limited | Other services | 2010 |
| THE Hearing Centres Ltd | Wholesale & retail | 2023 |
| THE Hera Barbers Ltd | Other services | 2020 |
| THE Kerrygold Company Limited | Professional & scientific | 1973 |
| THE Learning Mill Ltd | Health & social care | 2010 |
| THE Leek & Moorlands Historic Buildings Trust | Wholesale & retail | 1995 |
| THE Maude Leek Ltd | Information & communication | 2021 |
| THE Nursery at Old Hall Ltd | Wholesale & retail | 2017 |
| THE Oaks Brewing Company Ltd | Manufacturing | 2017 |
| THE Outdoors Initiative Community Interest Company | Education | 2024 |
| THE Parkers Newsagents Ltd | Wholesale & retail | 2021 |
| THE Peak Climbing School Ltd | Education | 2021 |
| THE Phone NET (UK) Limited | Information & communication | 2003 |
| THE Portland Dyeing Company Limited | Other services | 1990 |
| THE Queen of the Moorlands Whisky Company Ltd | Wholesale & retail | 2005 |
| THE Reform Holdings Limited | Financial services | 2024 |
| THE Reform Inn Limited | Hospitality | 2023 |
| THE Reformer Pilates Studio (Leek) Ltd | Arts & recreation | 2025 |
| THE Saltworks Trading Company Ltd | Other services | 2012 |
| THE Silk House Hotel Leek Limited | Hospitality | 2020 |
| THE Staffordshire Brewery Limited | Manufacturing | 2002 |
| THE Talentum Learning Trust | Education | 2016 |
| THE Wine Shop (Leek) Limited | Wholesale & retail | 2004 |
| Third Time Limited | Hospitality | 2021 |
| Thorney Leigh Construction Limited | Construction | 2001 |
| Thornton Estates Ltd | Financial services | 2026 |
| THQ Leek Ltd | Arts & recreation | 2017 |
| Three Horseshoes Inn Limited | Hospitality | 2003 |
| Thriveheim Ltd | Education | 2025 |
| Thyme Holdings Ltd | Financial services | 2023 |
| Tigerbite ST13 Ltd | Hospitality | 2024 |
| Tillie Williams Farm Consultancy Ltd | Professional & scientific | 2026 |
| Tittesworth Water Sports Limited | Administrative & support | 2017 |
| TJB Property Development Limited | Construction | 2024 |
| Today Food Barnsley Ltd | Hospitality | 2026 |
| Today Food Macclesfield Ltd | Hospitality | 2026 |
| Today Food Telford Ltd | Hospitality | 2026 |
| Tola Transport Ltd | Transport & logistics | 2014 |
| Tomar Corporate Finance Limited | Professional & scientific | 2012 |
| Tomoto Ltd | Wholesale & retail | 2016 |
| Tony Cornes Ltd | Professional & scientific | 2025 |
| Top Cars (NW) Limited | Administrative & support | 2016 |
| Top Cars Cheshire Ltd | Administrative & support | 2021 |
| Top Rock Properties Limited | Real estate | 2021 |
| Top Tier Trading Cards Ltd | Wholesale & retail | 2025 |
| Topcorner Hospitality Limited | Arts & recreation | 2012 |
| Total Fabric Solutions Limited | Administrative & support | 2001 |
| Totally Locally Leek CIC | Administrative & support | 2021 |
| Town and Country Pest Control Limited | Administrative & support | 2025 |
| TPA Wetley Rocks Ltd | Hospitality | 2025 |
| Tractive Power Limited | Manufacturing | 2008 |
| Tradingonestep Ltd | Wholesale & retail | 2026 |
| Transport KOT Ltd | Transport & logistics | 2025 |
| Trasada Limited | Education | 2012 |
| Treble Leek Ltd | Hospitality | 2025 |
| Tree Heritage Limited | Agriculture & fishing | 1982 |
| Trendy Timber Limited | Administrative & support | 2007 |
| Trinity Group NW Ltd | Financial services | 2023 |
| Trinity Group NW Property Management Ltd | Real estate | 2025 |
| Trio Stories Limited | Professional & scientific | 2023 |
| Truck & Parts (Staffs) Ltd | Wholesale & retail | 2015 |
| Truck Tyre Fleet Services Ltd | Manufacturing | 2025 |
| Truenorth Energy Staffs Limited | Construction | 2025 |
| TSB Studio Ltd | Other services | 2025 |
| TT Travel Adventure Ltd | Information & communication | 2026 |
| TTS Exports Limited | Wholesale & retail | 2000 |
| TTS Volvo Trucks Ltd | Professional & scientific | 2008 |
| Tumbili Kidogo Ltd | Information & communication | 2024 |
| Turborig Ltd | Wholesale & retail | 2026 |
| Two Tyred Ltd | Wholesale & retail | 2021 |
| TZH Ltd | Professional & scientific | 2011 |
| UK Medical & Event Services Ltd | Health & social care | 2016 |
| UP Close and... Productions Limited | Information & communication | 2022 |
| Urban Vision Enterprise CIC | Construction | 2011 |
| UVE Planning Ltd | Construction | 2023 |
| Valiant Group Ltd | Wholesale & retail | 2026 |
| Vampire Install Ltd | Construction | 2023 |
| Vape Station Leek Ltd | Wholesale & retail | 2022 |
| Vdas Consulting Engineers Ltd | Professional & scientific | 2021 |