| Shire Catering Equipment Ltd | Manufacturing | 2016 |
| Shire Joinery & Kitchens Ltd | Construction | 2022 |
| Shire Oak Court (Property) Limited | Households | 2010 |
| Shire Oak Driving School Limited | Education | 2009 |
| Shire Oak Road (Moorbank) Management Company Limited | Households | 1984 |
| Shire Residential Ltd | Real estate | 2023 |
| Shire Timber & Truss Limited | Manufacturing | 1995 |
| Shire Timber Group Holdings Limited | Financial services | 2018 |
| Shire Timber Group Limited | Financial services | 1999 |
| Shire Timber Structures Limited | Manufacturing | 2000 |
| Shireen NUR Artistry Ltd | Other services | 2026 |
| Shires Organ Pipes Limited | Manufacturing | 2005 |
| Shiris Bites Limited | Hospitality | 2026 |
| Shirley Technologies Limited | Professional & scientific | 2003 |
| Shiset Ltd | Hospitality | 2025 |
| Shiv Ganesh Retail Ltd | Wholesale & retail | 2024 |
| Shiv Infotec Ltd | Information & communication | 2020 |
| Shiv Krupa House Ltd | Real estate | 2022 |
| Shivaay Retails Limited | Wholesale & retail | 2025 |
| Shivam IT Consulting Services Ltd | Information & communication | 2019 |
| Shivani Clothing Limited | Wholesale & retail | 2025 |
| Shivashambo Cleaning Ltd | Administrative & support | 2024 |
| Shivhan Enterprise Ltd | Wholesale & retail | 2024 |
| Shivin Sweets & Bites Ltd | Manufacturing | 2026 |
| Shivni Limited | Financial services | 2026 |
| SHK Legal Limited | Professional & scientific | 2024 |
| SHK Traders Ltd | Wholesale & retail | 2021 |
| SHM Limited | Real estate | 2026 |
| Shoaib Adeeb Ltd | Wholesale & retail | 2025 |
| Shoaib Malik Limited | Health & social care | 2023 |
| Shoaib Trading Limited | Wholesale & retail | 2014 |
| Shoaiboo Ltd | Wholesale & retail | 2025 |
| Shoc Furniture Limited | Wholesale & retail | 2018 |
| Shock Horror Productions Ltd | Arts & recreation | 2023 |
| Shockwave Electrical Ltd | Construction | 2022 |
| Shoka Consulting Ltd | Information & communication | 2005 |
| Shokupan Ltd | Hospitality | 2022 |
| Sholimma Holdings Ltd | Real estate | 2020 |
| Sholkem Chemie Associates Limited | Professional & scientific | 2006 |
| Shonk Property Ltd | Real estate | 2020 |
| Shook Ltd | Administrative & support | 2019 |
| Shoon Street Lane Ltd | Wholesale & retail | 2025 |
| Shootconnect Ltd | Manufacturing | 2019 |
| Shooters Birmingham Limited | Real estate | 2020 |
| Shop Local Express Ltd | Wholesale & retail | 2026 |
| Shop on the Hill Horsforth Ltd | Wholesale & retail | 2024 |
| Shopbox Systems Limited | Extraterritorial | 2001 |
| Shopconvert Ltd | Information & communication | 2023 |
| Shopcrate Ltd | Wholesale & retail | 2025 |
| Shopdaughter Ltd | Wholesale & retail | 2020 |
| Shopfitting&Maintenance Ltd | Construction | 2017 |
| Shopikings Ltd | Information & communication | 2025 |
| Shopingly Ltd | Wholesale & retail | 2026 |
| Shopper Behaviour Ltd | Professional & scientific | 2025 |
| Shopper Retail Insight Limited | Information & communication | 2015 |
| Shoppers Delight Ltd | Wholesale & retail | 2024 |
| Shoppingflyest Ltd | Wholesale & retail | 2026 |
| Shoprize Ltd | Wholesale & retail | 2025 |
| Shopsterhub Ltd | Wholesale & retail | 2026 |
| Shore-Up CIC | Health & social care | 2021 |
| Shoreside Associates Ltd | Hospitality | 2019 |
| Shorething Communications Ltd | Information & communication | 2024 |
| Short Stays Ltd | Real estate | 2025 |
| Short Straw Skateboards Ltd | Manufacturing | 2023 |
| Shosheva Limited | Administrative & support | 2022 |
| Shot Blast Media Holdings Limited | Real estate | 2021 |
| Shot Blast Media Ltd | Information & communication | 2012 |
| Shot by Sodium Limited | Information & communication | 2011 |
| Shot From the Street Limited | Professional & scientific | 2016 |
| Shot in the Dark Game Ltd | Manufacturing | 2020 |
| Shot of the Block Ltd | Information & communication | 2016 |
| SHOULDER2WRIST Limited | Health & social care | 2017 |
| Shoulderdolly (UK) Limited | Wholesale & retail | 2009 |
| Shoutingjungle Ltd | Wholesale & retail | 2022 |
| Shovelfood Ltd | Hospitality | 2015 |
| Show + Tell Limited | Professional & scientific | 2009 |
| Show Properties Ltd | Real estate | 2026 |
| Showcase Pallets (UK1) Ltd | Manufacturing | 2020 |
| Shower People Limited | Construction | 2016 |
| Showers of Mercy Ministries | Other services | 2007 |
| Showoff Design and Display Limited | Administrative & support | 2005 |
| Showpiece Flooring Ltd | Construction | 2004 |
| Shred Sports Nutrition Ltd | Wholesale & retail | 2015 |
| Shree IT Services PVT Ltd | Information & communication | 2018 |
| Shree Khatu Shyam Parivar UK CIC | Education | 2025 |
| Shree RAM Ltd | Real estate | 2023 |
| Shree SAI (Bolton) Ltd | Wholesale & retail | 2019 |
| Shree SAI Healthcare Ltd | Health & social care | 2021 |
| Shri Ganesh SAI Malik Properties Ltd | Construction | 2023 |
| Shri Narayana UK Ltd | Wholesale & retail | 2025 |
| Shri Radha Ltd | Wholesale & retail | 2024 |
| Shri SAI Properties Ltd | Real estate | 2013 |
| Shristi Ltd | Information & communication | 2025 |
| Shrthebrand Ltd | Wholesale & retail | 2025 |
| SHS Property Development Limited | Extraterritorial | 2012 |
| SHS Utilities Limited | Construction | 2011 |
| Shsk Ltd | Health & social care | 2017 |
| Shuan Enterprises UK Ltd | Wholesale & retail | 2024 |
| Shuang HSI Limited | Hospitality | 2019 |
| Shubdot Limited | Health & social care | 2022 |