| Shellbourne Properties Limited | Construction | 2002 |
| Shelldeck Safety Systems Limited | Administrative & support | 2018 |
| Shellshock Limited | Information & communication | 2003 |
| Shelly's Home Garden & Pet Supplies Ltd | Wholesale & retail | 2025 |
| Shelnic Solutions Limited | Professional & scientific | 2020 |
| Sheltec Limited | Construction | 1993 |
| Shelton Homes Limited | Real estate | 2026 |
| Shelving & Racking Limited | Manufacturing | 2010 |
| Shenward (Leeds) Limited | Professional & scientific | 2011 |
| Shenward Company Secretarial Services Limited | Extraterritorial | 2016 |
| Shepherd & Sons Transport Ltd | Transport & logistics | 2020 |
| Shepherd Capital Limited | Professional & scientific | 2000 |
| Shepherd Gilmour (Leeds) Limited | Professional & scientific | 2001 |
| Shepherd Gilmour Estates and Facilities Limited | Administrative & support | 2025 |
| Shepherd Hart Services Ltd | Energy | 2025 |
| Shepherd House Apartments Ltd | Real estate | 2025 |
| Shepherd House Deerness Ltd | Extraterritorial | 1976 |
| Shepherd Mabuto Limited | Construction | 2012 |
| Shepherd Productions Limited | Information & communication | 2008 |
| Shepherd Projects Limited | Professional & scientific | 2000 |
| Shepherd Ventures Limited | Professional & scientific | 2000 |
| Shepherds Footwear Limited | Real estate | 2002 |
| Shepherds Place Limited | Real estate | 2016 |
| Shepherds Place Property Sourcing Services Ltd | Other services | 2019 |
| Shepley Engineers Limited | Manufacturing | 1994 |
| Sheppard Planning Ltd | Professional & scientific | 2020 |
| Shepperton Shutters Ltd | Manufacturing | 2025 |
| Sheqe Ltd | Wholesale & retail | 2018 |
| Sher Property Group Ltd | Real estate | 2025 |
| Sher-E-Panjab Ltd. | Health & social care | 2022 |
| Sher-E-Panjab Properties Ltd | Real estate | 2025 |
| Shera Properties Limited | Real estate | 2020 |
| Sherbet Salon Services Limited | Other services | 2019 |
| Sherburn Barbers Ltd | Other services | 2026 |
| Sherburn Cars and Light Commercials Limited | Wholesale & retail | 1995 |
| Sherburn Commercial Properties Limited | Real estate | 2016 |
| Sherburn Community Gymnastics Club Ltd. | Arts & recreation | 2016 |
| Sherburn Engineering Limited | Transport & logistics | 1985 |
| Sherburn Together Support Hub CIC | Other services | 2026 |
| Sherburn White Rose Football Club C.I.C. | Arts & recreation | 2026 |
| Sheridan Design Ltd | Professional & scientific | 2024 |
| Sheridan Fire Protection & Pipework Limited | Administrative & support | 2004 |
| Sheridan Properties North Ltd | Real estate | 2023 |
| Sherifj Limited | Professional & scientific | 2021 |
| Sheringham Haulage Ltd | Transport & logistics | 2014 |
| Sherlock Holdings Ltd | Construction | 2017 |
| Shermont Oakwood Ltd | Real estate | 2021 |
| Shernex Limited | Health & social care | 2025 |
| Sheru Limited | Real estate | 2026 |
| Sherwood Caravan Storage Limited | Real estate | 2015 |
| Sherwood Clinical Services Ltd | Wholesale & retail | 2017 |
| Sherwood Cowlin Investments Limited | Real estate | 2011 |
| Sherwood Fireplaces & Stoves Ltd | Construction | 2013 |
| Sherwood Grange Ltd. | Health & social care | 2012 |
| Sherwood Test Services Ltd | Information & communication | 2021 |
| Shetherland Ltd | Real estate | 2022 |
| Shevill and Bradd Limited | Professional & scientific | 1964 |
| Shewit Ltd | Health & social care | 2022 |
| Shex Mini Market Ltd | Wholesale & retail | 2025 |
| Shex Pharma Ltd | Health & social care | 2023 |
| Sheyda Ltd | Wholesale & retail | 2025 |
| SHF Properties Ltd | Real estate | 2022 |
| Shgo Consultancy Limited | Professional & scientific | 2025 |
| Shield Auditing Limited | Professional & scientific | 2022 |
| Shield Damp Proofing Limited | Construction | 2013 |
| Shield Law Ltd | Professional & scientific | 2024 |
| Shield Property Sales LLP | | 2008 |
| Shield Recruitment Limited | Administrative & support | 2013 |
| Shields Homes Limited | Real estate | 2025 |
| Shifa Medical Limited | Wholesale & retail | 2006 |
| Shift IT Vehicle Logistics Limited | Transport & logistics | 2025 |
| Shift Technologies Limited | Information & communication | 2012 |
| Shifting the Perception of Type One Diabetes CIC | Wholesale & retail | 2024 |
| Shiftra Ltd | Administrative & support | 2025 |
| Shillims Ltd | Construction | 2023 |
| Shillito Industrial Roofing Limited | Construction | 2005 |
| Shimla Spice Ltd | Hospitality | 2019 |
| Shine Bright (NS) C.I.C. | Health & social care | 2019 |
| Shine Clinical Ltd | Information & communication | 2020 |
| Shine Labs Ltd | Professional & scientific | 2013 |
| Shine My Ride & Car Sales Ltd | Administrative & support | 2021 |
| Shine Property Holdings Limited | Real estate | 2016 |
| Shine Sparkle Clean Limited | Administrative & support | 2025 |
| Shine: Support and Help in Education | Education | 2000 |
| Shining Star Enterprise Limited | Information & communication | 2012 |
| Shining Star Tuition Centre Ltd | Education | 2020 |
| Shinning Majestic | Arts & recreation | 2026 |
| Shinonome Properties Ltd | Real estate | 2024 |
| Shiny Sky Limited | Transport & logistics | 2004 |
| Shipin Automatic Ltd | Wholesale & retail | 2026 |
| Shipley Building Plastics Limited | Wholesale & retail | 2022 |
| Shipley FAN Company,Limited(The) | Manufacturing | 1945 |
| Shipley Healthcare Limited | Wholesale & retail | 2023 |
| Shipleys Accounting Ltd | Professional & scientific | 2023 |
| Shipleys Tax Accounting Limited | Professional & scientific | 2024 |
| Shipleys Tax Accounts Limited | Professional & scientific | 2024 |
| Shipleys Tax Consulting Limited | Professional & scientific | 2004 |
| Shipleys Tax Group Limited | Financial services | 2026 |
| Shiraz a Limited | Hospitality | 2025 |
| Shiraz UK Food Ltd | Hospitality | 2024 |