| Designwrite Signs Ltd | Professional & scientific | 2013 |
| Desire Drop Aesthetics Ltd | Other services | 2025 |
| Desk Top Publishing Micro Systems Limited | Information & communication | 1992 |
| Desma Afro Shop Ltd | Wholesale & retail | 2026 |
| Desmond J. Smail Limited | Wholesale & retail | 2002 |
| Desres Yorkshire Ltd | Administrative & support | 2013 |
| Destination Properties Ltd | Real estate | 2020 |
| Destinationbakes Ltd | Wholesale & retail | 2026 |
| Destiny Healthcare Ltd | Health & social care | 2021 |
| Destiny Medical Ltd | Health & social care | 2022 |
| Destitche Ltd | Wholesale & retail | 2025 |
| Destra Capital Limited | Professional & scientific | 2025 |
| Destra Limited | Professional & scientific | 2025 |
| Desvernay Ltd | Real estate | 2022 |
| Desweet Limited | Hospitality | 2025 |
| Detail Production LLP | | 2010 |
| Detroit Pizzas Leeds Ltd | Hospitality | 2024 |
| Dettmer Management Consultancy Ltd | Administrative & support | 2017 |
| DEU Commercial Limited | Real estate | 2016 |
| DEU Estates Holdings Limited | Real estate | 2016 |
| DEU Estates Limited | Real estate | 2020 |
| DEU Estates Residential Limited | Real estate | 2016 |
| DEU Health Limited | Health & social care | 2007 |
| Deuren Limited | Wholesale & retail | 2013 |
| DEV Fish Limited | Information & communication | 2017 |
| DEV Haus Ltd | Information & communication | 2025 |
| DEV Sharma Medical Consultation Ltd | Professional & scientific | 2024 |
| Dev-Wp Ltd | Professional & scientific | 2023 |
| Devbeans Digital Limited | Information & communication | 2026 |
| Develop Software Ltd | Information & communication | 2018 |
| Development and Renovation Limited | Real estate | 2012 |
| Development Training Solutions Ltd | Education | 2009 |
| Developments 313 Ltd | Construction | 2026 |
| Developments by HSS Limited | Real estate | 2025 |
| Develp Media Limited | Information & communication | 2022 |
| Devesh Locum Services Ltd | Wholesale & retail | 2023 |
| Devika RAO Dance Theatre Limited | Arts & recreation | 2021 |
| Devine Definition Ltd | Other services | 2025 |
| Devine Investment Corp Limited | Administrative & support | 2025 |
| Devise Ltd | Information & communication | 2025 |
| Devon Food Group Limited | Hospitality | 2025 |
| Devondemand UK Ltd | Information & communication | 2022 |
| Devonshire Flats Limited | Other services | 2005 |
| Devonshire Gardens (Crich) Management Company Limited | Households | 2014 |
| Devonshire Gent Limited | Other services | 2022 |
| Devonshire Heart Ltd | Health & social care | 2019 |
| Devonshire Lane Bidco Ltd | Extraterritorial | 2023 |
| Devonshire Lane Propco Limited | Extraterritorial | 2023 |
| Devops Engineers Limited | Information & communication | 2019 |
| Devport Consulting Ltd | Transport & logistics | 2022 |
| Devstack Consultancy Limited | Professional & scientific | 2013 |
| DEW Construction Limited | Wholesale & retail | 1934 |
| DEW Drops Publishing Ltd | Information & communication | 2021 |
| DEW YOU Ltd | Extraterritorial | 2024 |
| Dewalt Ltd | Wholesale & retail | 2025 |
| Dewdrop Pharma Ltd | Wholesale & retail | 2019 |
| Dewfield | | 1976 |
| Dewhirst Building Freehold Limited | Households | 2025 |
| Dewillon Properties Limited | Real estate | 1973 |
| Dewlon Limited | Real estate | 2011 |
| Dewsbury Desserts Ltd | Hospitality | 2016 |
| Dewsbury Law Ltd | Professional & scientific | 2020 |
| Dewsbury Road Foods & Wine Ltd | Wholesale & retail | 2025 |
| Dewsbury Shaw Limited | Health & social care | 2025 |
| Dewster Limited | Health & social care | 2021 |
| Deww Ltd | Construction | 2022 |
| Dexperts Ltd | Information & communication | 2024 |
| Dexter Nicholas Limited | Administrative & support | 2008 |
| Dexter Property Developments Limited | Construction | 2022 |
| Dexzent Cleaning Service Limited | Administrative & support | 2025 |
| Dezign Space Limited | Information & communication | 2020 |
| DF Eldon Ltd | Real estate | 2018 |
| DF Glasgow Ltd | Real estate | 2018 |
| DF Housing Ltd | Real estate | 2025 |
| DF Mortgage & Protection Specialists Ltd | Financial services | 2025 |
| DF Stanmore Ltd | Real estate | 2018 |
| DF Temple Ltd | Real estate | 2018 |
| DF Trading LLP | | 2005 |
| DF Trading Property Lets Ltd | Real estate | 2024 |
| DFC Education Consultancy Ltd | Education | 2018 |
| DFC EOT Limited | Extraterritorial | 2024 |
| DFG Technology Ltd | Information & communication | 2015 |
| Dfgb Premium Trading Limited | Wholesale & retail | 2023 |
| DFN Consultants Ltd | Professional & scientific | 2015 |
| DFO 123 Ltd | Financial services | 2025 |
| DFP Healthcare Limited | Health & social care | 2021 |
| DFR1 Ltd | Other services | 2012 |
| DFS Furniture Online Ltd | Wholesale & retail | 2010 |
| Dfscaffolding Ltd | Construction | 2023 |
| DG Desserts Ltd | Hospitality | 2020 |
| DG Intellectual Limited | Extraterritorial | 2010 |
| DG Premier Properties Ltd | Real estate | 2025 |
| DG Testing Ltd | Construction | 2018 |
| DG Training Limited | Education | 2022 |
| DGA Wood Fuels Limited | Manufacturing | 2015 |
| DGC Properties and Investments Limited | Real estate | 2022 |
| DGL Homes Limited | Real estate | 2024 |
| DGM Projects Ltd | Professional & scientific | 2026 |
| DGN Coffee Roastery Ltd | Hospitality | 2025 |
| DGR (UK) Limited | Real estate | 2004 |