| Stitch-Tech Limited | Manufacturing | 2007 |
| Stockdale Estates Limited | Real estate | 2000 |
| Stockexecutiveresource Ltd | Administrative & support | 2022 |
| Stokesy & Co. Estates Limited | Real estate | 2012 |
| Stoliv Limited | Professional & scientific | 2014 |
| Stone House Collection Ltd | Real estate | 2026 |
| Stone Yard Court Management Company Limited | Households | 1989 |
| Stop the Rock Furniture Limited | Wholesale & retail | 1997 |
| Storage Methods Limited | Professional & scientific | 1964 |
| Stormlight Group Ltd. | Information & communication | 2024 |
| Storrtop Ltd | Professional & scientific | 2021 |
| Stotties of Rugby Limited | Hospitality | 2023 |
| Strange PR Limited | Professional & scientific | 2007 |
| Strata Sales Ltd | Wholesale & retail | 2019 |
| Strata UK Holdings Ltd | Wholesale & retail | 2019 |
| Stratallen Limited | Extraterritorial | 2025 |
| Strategic Edge Consulting Group Ltd | Professional & scientific | 2024 |
| Strategic Solutions ABC Ltd | Professional & scientific | 2025 |
| Strategy Haynes Ltd | Professional & scientific | 2020 |
| Strategy Haynes SPV Ltd | Real estate | 2025 |
| Stratford Glass Ltd | Manufacturing | 1999 |
| Stratford Landscapes Ltd | Other services | 2011 |
| Stratford Preparatory School Limited | Education | 1988 |
| Stratford Structural Limited | Construction | 2019 |
| Stratford-Upon-Avon RDA | Health & social care | 2011 |
| Straub Properties Limited | Real estate | 2025 |
| Streetwise Couriers Midlands Ltd | Extraterritorial | 2019 |
| Strengthspaces Ltd | Arts & recreation | 2026 |
| Stride Consulting Ltd | Professional & scientific | 2018 |
| Stride Teamwear Suppliers Ltd | Wholesale & retail | 2025 |
| Strongher Coaching Ltd | Education | 2026 |
| Stronghold Technologies Limited | Manufacturing | 2022 |
| Strongman Lifts Limited | Administrative & support | 2023 |
| Strongman Tools Limited | Administrative & support | 1998 |
| Studio 15 Limited | Professional & scientific | 2019 |
| Studio 49 Nails Limited | Other services | 2019 |
| Studio Nota Limited | Professional & scientific | 2026 |
| Studio Workshop Limited | Manufacturing | 2023 |
| Studio Worx Leamington Ltd | Arts & recreation | 2020 |
| Stunning Style Events Limited | Hospitality | 2025 |
| Stvdio Expert Limited | Manufacturing | 2016 |
| Stylemistress Ltd | Arts & recreation | 2024 |
| Stylus One Limited | Administrative & support | 2012 |
| SU Marketing Ltd | Wholesale & retail | 2024 |
| SUB Zero Concept Modelling Limited | Professional & scientific | 2013 |
| Subaj Capital UK Limited | Professional & scientific | 2016 |
| Subedars Indian Gastropub Limited | Hospitality | 2024 |
| Subpoena Limited | Wholesale & retail | 2010 |
| Success Inspired Limited | Wholesale & retail | 2013 |
| Summerbud Limited | Wholesale & retail | 2015 |
| Summerline Aviation Ltd | Administrative & support | 2007 |
| Sun and Glory Ltd | Real estate | 2022 |
| Sun Coffee Ltd | Administrative & support | 2020 |
| Sun-Ray Blinds and Shutters Limited | Construction | 2005 |
| Sunbeams Pre-School (Radford Semele) | Education | 2010 |
| Suncliffe Holdings Ltd | Financial services | 2021 |
| Sundarambrothers Ltd | Wholesale & retail | 2015 |
| Sunlikeshine Ltd | Information & communication | 2018 |
| Sunny Brew Ltd | Hospitality | 2024 |
| Sunpearl Investments Ltd | Financial services | 2010 |
| Sunrise Black Ltd | Professional & scientific | 2025 |
| Sunshare Limited | Households | 1998 |
| Sunspire Ltd | Wholesale & retail | 2026 |
| Super Charge Energy Limited | Professional & scientific | 2017 |
| Super Spline Studios Ltd | Information & communication | 2016 |
| Superior Solar Solutions Ltd | Energy | 2024 |
| Supersonic House Ltd | Real estate | 2021 |
| Supersonic Sameday UK Limited | Transport & logistics | 2008 |
| Superstar Bots Ltd | Professional & scientific | 2019 |
| Supplegents Limited | Wholesale & retail | 2025 |
| Support With Stuff Ltd | Administrative & support | 2018 |
| Supreme Windscreens Limited | Wholesale & retail | 2012 |
| Sure ICT Solutions Limited | Information & communication | 2012 |
| Sure Midlands Ltd | Construction | 2024 |
| Sure Plan Construction Services Ltd | Construction | 2022 |
| Surestars Day Nursery Limited | Education | 2009 |
| Surgery KIT Ltd | Administrative & support | 2012 |
| Sustain Life Ltd | Wholesale & retail | 2018 |
| Sustainable Lighting Solutions Group Limited | Construction | 2025 |
| Sustainable Lighting Solutions Ltd | Construction | 2018 |
| Sustainable Venues Ltd | Professional & scientific | 2011 |
| Sutton Sustainability Solutions Ltd | Professional & scientific | 2015 |
| Suyatha Ltd | Wholesale & retail | 2019 |
| Suyatha Property Ltd | Real estate | 2026 |
| SW Active Limited | Arts & recreation | 2012 |
| Swabhiman Ltd | Real estate | 2020 |
| Swagat Restaurants Limited | Hospitality | 2025 |
| Swamnd Services Limited | Construction | 2022 |
| Sweeneys Martial Arts Ltd | Arts & recreation | 2024 |
| Sweet Track Limited | Information & communication | 2023 |
| Swift Assist Limited | Administrative & support | 2016 |
| Swinbrook Consulting Limited | Professional & scientific | 2023 |
| Swinburne Ltd | Professional & scientific | 2025 |
| Switch Limited | Extraterritorial | 2026 |
| Switch Squid Ltd | Information & communication | 2021 |
| Switchgear Systems Limited | Wholesale & retail | 2003 |
| Sword Scientific Limited | Wholesale & retail | 2006 |
| Swordfish Marketing Ltd | Professional & scientific | 2006 |
| Sycamore Real Estate Group Limited | Real estate | 2024 |
| Sydenham Autos Ltd | Wholesale & retail | 2026 |