| Cyril Jones Painting Contractors Limited | Construction | 2014 |
| CZE Ltd | Professional & scientific | 2001 |
| Czworks Limited | Information & communication | 2003 |
| D & E Wilson & Sons Limited | Manufacturing | 1995 |
| D & F Mcgrath (House Builders) Limited | Wholesale & retail | 2002 |
| D & G Builders and Joiners Limited | Construction | 1995 |
| D & G Sunbeds Limited | Administrative & support | 2002 |
| D & J Auto-Electrical Services Ltd. | Wholesale & retail | 2003 |
| D & L Designs Limited | Manufacturing | 2003 |
| D & M Food Supplies Limited | Wholesale & retail | 2007 |
| D & M Pitt (Painting and Decorating) Limited | Construction | 1994 |
| D & T Trading Limited | Professional & scientific | 2020 |
| D a Layland Ltd | Transport & logistics | 2007 |
| D Fuce Precision Engineering Ltd | Professional & scientific | 2007 |
| D Haynes Limited | Manufacturing | 1979 |
| D Hodgkin Maintenance & Building Services Ltd | Construction | 2007 |
| D Hollowell and Sons Ltd. | Other services | 2001 |
| D J Lingard & Associates Ltd | Construction | 2000 |
| D S Bristol Limited | Administrative & support | 2002 |
| D T Law Butchers Limited | Wholesale & retail | 2002 |
| D-Fit Wardrobes Limited | Manufacturing | 2002 |
| D. Clay Limited | Hospitality | 2002 |
| D. Gillespie Limited | Wholesale & retail | 1999 |
| D. L. (Civil Engineering) Ltd | Construction | 2006 |
| D. R. Floors Limited | Construction | 2006 |
| D. Topping Limited | Health & social care | 2003 |
| D.A.(Dan)Kerr Limited | Construction | 1957 |
| D.D.M.C. Limited | Real estate | 1995 |
| D.J.B Tree Specialist Limited | Administrative & support | 2003 |
| Dagda Limited | Information & communication | 2002 |
| Daisy Chain (Burnley) Limited | Wholesale & retail | 2007 |
| Dale Builders & Civil Engineers Ltd | Construction | 2005 |
| Dales Renewables Limited | Wholesale & retail | 2007 |
| Daleview Properties Limited | Real estate | 2003 |
| Dallimore Ceilings Ltd | Construction | 2007 |
| Damville Ltd | Extraterritorial | 2007 |
| DAN Kerr Property Services Limited | Construction | 1997 |
| Dan's Fish Limited | Wholesale & retail | 2003 |
| Daniel James Hairdressing Limited | Other services | 2005 |
| Danwell Trading Limited | Real estate | 1986 |
| Darby Estates Limited | Real estate | 1992 |
| Darwen Carpets Limited | Construction | 2002 |
| Datacenta Limited | Information & communication | 2003 |
| Dave Barton Construction Limited | Construction | 2003 |
| Dave Gotto's Barber Shop Limited | Other services | 2002 |
| Dave Wensley Plant Hire Limited | Administrative & support | 2004 |
| David Batty Ltd | Information & communication | 1994 |
| David Goodger & Associates Limited | Professional & scientific | 2002 |
| David Henderson Optical Ltd | Wholesale & retail | 2016 |
| David Marshall Consultants Limited | Professional & scientific | 2004 |
| David Procter Accountancy Services Ltd | Professional & scientific | 2003 |
| David Randerson Design Associates Limited | Professional & scientific | 1989 |
| David Whittaker Homes Ltd | Real estate | 2006 |
| David Wood Optical Ltd | Wholesale & retail | 2017 |
| Dawn TIL Dusk PLC | Transport & logistics | 1986 |
| Daws FRY & Co Accounting & Taxation Services Limited | Information & communication | 2001 |
| Daylesford Associates Limited | Health & social care | 2008 |
| DDL Davies Limited | Wholesale & retail | 2003 |
| DE & K Lister & SON Limited | Wholesale & retail | 2001 |
| Dean Cocozza Limited | Other services | 2004 |
| Deanne's Hair Salon Limited | Administrative & support | 2006 |
| Dehn (U.K.) Ltd. | Wholesale & retail | 1994 |
| Delbee Limited | Professional & scientific | 2005 |
| Deluxe Designs Limited | | 1995 |
| Derby Ward Building Preservation Trust | Extraterritorial | 2007 |
| Derek's Carpet Cleaners Limited | Administrative & support | 2003 |
| Derell Consultants Ltd | Professional & scientific | 2005 |
| DES Conway Building & Roofing Limited | Construction | 2002 |
| Desai Properties Limited | Real estate | 1991 |
| Desert Daffodil Limited | Arts & recreation | 1995 |
| Design & Form Limited | Manufacturing | 1983 |
| Design Dynamos Limited | Information & communication | 2002 |
| Desire International UK Limited | Wholesale & retail | 2006 |
| Detect Fire and Security Ltd | Extraterritorial | 2005 |
| Devdemesne Ltd | Information & communication | 2006 |
| Devonshire Blinds Ltd | Wholesale & retail | 2003 |
| Devonshire Garage Ltd | Manufacturing | 2007 |
| Deyplas Limited | Construction | 2002 |
| DG Construction Limited | Construction | 2002 |
| DHE Solutions Ltd | Education | 2003 |
| Diagnostic Hearing Ltd | Wholesale & retail | 2018 |
| Dickie Tours Limited | Administrative & support | 2002 |
| DIG IT Plant Hire (Lancashire) Limited | Construction | 2004 |
| Digitexa Ltd | Other services | 2025 |
| Dignity (Worldwide) | Other services | 2007 |
| Dignity Wigs Ltd | Wholesale & retail | 2006 |
| Dipali Limited | Hospitality | 1997 |
| Directed Printing Services Limited | Manufacturing | 1994 |
| Disability Bathrooms (Thornton) Limited | Construction | 2007 |
| Disc Covery Records Limited | Wholesale & retail | 2003 |
| Discounted Plastics Limited | Wholesale & retail | 2009 |
| Dispatcherdart Ltd | Wholesale & retail | 2025 |
| Dixon Engineering (Lancs) Limited | | 1973 |
| Dlh.Com Limited | Transport & logistics | 2007 |
| DM Film Productions Ltd | Information & communication | 2026 |
| DMR Construction Services Limited | Construction | 2001 |
| Dobege International Limited | Information & communication | 2002 |
| Dobege Photography Limited | Professional & scientific | 2007 |
| Dockside Limited | Manufacturing | 1981 |
| Dolphinstar Limited | Manufacturing | 2002 |