| Right Vibe Properties Limited | Real estate | 2016 |
| RIJ Investments Limited | Financial services | 2023 |
| Ringspun Apparel Limited | Wholesale & retail | 2015 |
| Ripstop LLP | | 2006 |
| Rische Limited | Construction | 1994 |
| Risk Control (Eh&S) Services Ltd | Extraterritorial | 2011 |
| Rita Ray's Ltd | Hospitality | 2025 |
| Ritas Kind Kitchen Ltd | Wholesale & retail | 2026 |
| River Lily Workshop Limited | Manufacturing | 2024 |
| Riverview Estate Management Limited | Real estate | 2026 |
| RJK (UK) INV Ltd | Professional & scientific | 2022 |
| RLB Investments Ltd | Real estate | 2020 |
| RLM Family Investment Ltd | Financial services | 2025 |
| RMW Holdings Limited | Professional & scientific | 2018 |
| Road Maintenance Services (Holdings) Limited | Financial services | 1947 |
| Road Maintenance Services (Preservations) Limited | Construction | 2018 |
| Road Maintenance Services Limited | Construction | 1987 |
| Robert Hughes Studio Limited | Professional & scientific | 2022 |
| Robert John Moore Limited | Real estate | 2018 |
| Roberta Beauty Redefined Ltd | Health & social care | 2017 |
| Robins Medical Limited | Health & social care | 2026 |
| Robins Properties Limited | Real estate | 2021 |
| Robinson Equestrian Ltd | Arts & recreation | 2024 |
| Rock a Card Ltd | Information & communication | 2017 |
| Rocket 66 Ltd | Construction | 2021 |
| Rockford Group Holdings Limited | Financial services | 2024 |
| Rockhold Investments Limited | Financial services | 2019 |
| Rockhold Solutions Group Limited | Financial services | 2021 |
| Rolls Refrigeration Limited | Other services | 1984 |
| Rong Guang Ltd | Hospitality | 2022 |
| Rooms in the Yard Limited | Wholesale & retail | 2019 |
| Roper Living Limited | Real estate | 2020 |
| Rose Anaesthetic Services Limited | Health & social care | 2017 |
| Rose Mountain Properties Limited | Real estate | 2025 |
| Roseburgh Investments Limited | Professional & scientific | 2022 |
| Rosemay (NW) LLP | | 2013 |
| Rosemay Holdings Ltd | Real estate | 2017 |
| Rosemont Reserve Limited | Professional & scientific | 2025 |
| Rosey Enterprises Limited | Real estate | 1999 |
| Roshban DY8 Ltd | Real estate | 2024 |
| Rosmat Ltd | Real estate | 2023 |
| Ross Miller Ltd | Professional & scientific | 2025 |
| Royal Court Knutsford Management Limited | Real estate | 1996 |
| RS Leonard Books Ltd | Information & communication | 2022 |
| RTG Limited | Construction | 2018 |
| Rthexton Ltd | Professional & scientific | 2023 |
| Rudyard Vale Limited | Hospitality | 2022 |
| Run Serve Health Physiotherapy Ltd | Health & social care | 2026 |
| Russell Maintenance Company Limited | Households | 1993 |
| Russet Gold Property Limited | Real estate | 2024 |
| Rutaxa Ltd | Professional & scientific | 2005 |
| Rutherford Drive Limited | Households | 2002 |
| Rutland Property Group Limited | Construction | 2014 |
| Ryan Egan Photography Ltd | Professional & scientific | 2024 |
| S E Enterprises Limited | Professional & scientific | 2005 |
| S Green Consultancy Ltd | Professional & scientific | 2024 |
| S.J. Gadgets Ltd | Wholesale & retail | 2019 |
| S1 Project Management Limited | Construction | 2018 |
| S2 Rentals Limited | Real estate | 2018 |
| S3 Developments Limited | Construction | 2012 |
| SA Healthcare Consulting Limited | Professional & scientific | 2023 |
| SA Truck & Crane Services Ltd | Construction | 2024 |
| Saeuroconsulting Ltd | Professional & scientific | 2024 |
| Safety First in Education Ltd | Education | 2020 |
| Sagp Advisory Limited | Professional & scientific | 2024 |
| SAI Street Partners Limited | Real estate | 2020 |
| Saint Paul International Limited | Real estate | 2021 |
| Salaris Services Limited | Administrative & support | 2010 |
| Salford Chiropractic Clinic Limited | Health & social care | 2015 |
| Sally a Smith Limited | Administrative & support | 2023 |
| Samantha Reid Ltd | Health & social care | 2026 |
| Samton Properties Ltd | Real estate | 2023 |
| Sandiway Solutions (NO 3) Limited | Financial services | 2004 |
| Sandymoor Local Centre Management Company Ltd | Households | 2021 |
| Sant & Birchall Property Holdings Limited | Wholesale & retail | 1998 |
| Sant Bros Limited | Administrative & support | 2003 |
| Santa Monica Wastelands Ltd | Arts & recreation | 2026 |
| Sapling Home Farm Ltd | Agriculture & fishing | 2024 |
| Sapphire Nails Ltd | Other services | 2024 |
| Sara Saad Limited | Health & social care | 2023 |
| Sarah Higgins Dressage International Limited | Professional & scientific | 2020 |
| Sarah Restrick Ltd | Hospitality | 2021 |
| Saving Grace Lifestyle Limited | Administrative & support | 2017 |
| Sawyers Candles Limited | Manufacturing | 2020 |
| Saxons Bolton (Management Company) Limited | Households | 2006 |
| SBM (Manchester) Limited | Professional & scientific | 2004 |
| Scale UK Holdings Limited | Financial services | 2025 |
| Scarlet Arch Consultancy Limited | Information & communication | 2023 |
| Schott House Management Limited | Real estate | 2025 |
| Scie Consulting Ltd | Professional & scientific | 2024 |
| Sciecom Limited | Administrative & support | 2021 |
| Scientech Limited | Administrative & support | 2014 |
| Scion Medica Limited | Professional & scientific | 2011 |
| Scoco Ltd | Professional & scientific | 2002 |
| Scored Spaces Ltd | Information & communication | 2026 |
| Scott Molloy Services Limited | Transport & logistics | 2017 |
| Scott Warrington Consulting Limited | Professional & scientific | 2026 |
| Scout Green Limited | Real estate | 2015 |
| SD Equestrian Services Ltd | Agriculture & fishing | 2023 |
| Seablue Services Ltd | Construction | 2019 |