| RAY Freeman Psychotherapy Limited | Education | 2012 |
| RDG Media Limited | Other services | 2022 |
| Real Time Embedded Ltd | Information & communication | 2024 |
| Reboot Group Ltd | Construction | 2025 |
| Red Cape Ltd | Professional & scientific | 2004 |
| Red Kite Day Care Nursery Limited | Education | 2008 |
| Redesign IT Limited | Professional & scientific | 2021 |
| Redkite Dynamics Limited | Professional & scientific | 2017 |
| Redline Collective Limited | Information & communication | 2021 |
| Redline Holdings Limited | Professional & scientific | 2015 |
| Redline Property Holdings Limited | Professional & scientific | 2015 |
| Redline Specialist Cars Limited | Wholesale & retail | 1997 |
| Refoveo Properties Ltd | Real estate | 2019 |
| Regal Driving School Limited | Education | 2025 |
| Remarkable Developments Ltd | Construction | 2018 |
| Remarkable Inc. Ltd | Administrative & support | 2016 |
| Remarkable Lets Ltd | Real estate | 2019 |
| Remarkable Property Investments LLP | | 2016 |
| Remarkable Serviced Accommodation Limited | Real estate | 2017 |
| Remarkable SM JV Ltd | Real estate | 2019 |
| Remarkable Ventures Ltd | Real estate | 2019 |
| Rents 4 YOU Ltd | Real estate | 2022 |
| Residential & Domestic Sprinklers Limited | Construction | 2020 |
| Residential Fire Protection Limited | Construction | 2016 |
| Resources and Carbon Management Services Ltd | Professional & scientific | 2019 |
| Reynard Fabrics Limited | Wholesale & retail | 1999 |
| RHS Group Ltd | Wholesale & retail | 2019 |
| Rialto Court Management Company Limited | Administrative & support | 2013 |
| Richard J Eaton Limited | Professional & scientific | 2019 |
| Richard Meynell Associates Limited | Other services | 2008 |
| RIF RAF Limited | Hospitality | 2021 |
| RIG Projects and Flooring Limited | Construction | 2020 |
| Ripley Training Limited | Real estate | 2006 |
| Riseholme Residents Management Company Limited | Real estate | 2010 |
| Riverside Quarry Limited | Wholesale & retail | 2010 |
| RJ Moon Ltd | Health & social care | 2019 |
| RJ Products Limited | Manufacturing | 2016 |
| RKD Motion Ltd | Information & communication | 2025 |
| RMB Financial Management (UK) Limited | Financial services | 2003 |
| RMH Research Ltd | Professional & scientific | 2023 |
| RMP Financial LLP | | 2010 |
| Robert Aagaard Ltd | Administrative & support | 2006 |
| Robert Hunter Plant Hire Limited | Administrative & support | 2017 |
| Roberts Aviation Solutions Limited | Professional & scientific | 2018 |
| Rockwood Financial Solutions Limited | Financial services | 2012 |
| Romelec Electrical Ltd | Construction | 2024 |
| Romelec Property Limited | Real estate | 2025 |
| ROO Maurice Ltd | Arts & recreation | 2020 |
| Rooftech 07 Ltd | Construction | 2026 |
| Roosters Brewery Limited | Manufacturing | 2011 |
| Roosters Brewing Company Limited | Manufacturing | 2000 |
| Rose Rock Acre Property Ltd | Hospitality | 2022 |
| Rosewood Window Cleaning Ltd | Administrative & support | 2024 |
| Ross Stewart Ltd | Education | 2012 |
| Rougham Farm Limited | Agriculture & fishing | 2016 |
| Round One Residentials Limited | Real estate | 2021 |
| Roundwood Car & Commercial Limited | Wholesale & retail | 2016 |
| Rutland Frederick Limited | Information & communication | 2002 |
| RVL Consulting Ltd | Professional & scientific | 2025 |
| Ryan Bloor Ltd | Information & communication | 2020 |
| S & RK Properties Limited | Real estate | 2022 |
| S Heerang Ltd | Hospitality | 2024 |
| S J Whitwham Accountants Limited | Professional & scientific | 2018 |
| S K Photo Limited | Professional & scientific | 2006 |
| S Westerman Ltd | Administrative & support | 2003 |
| Sableway Limited | Wholesale & retail | 2012 |
| Saffron Property Limited | Real estate | 2024 |
| Saint Bohemia Ltd | Wholesale & retail | 2020 |
| Sally Marie Scott Ltd | Hospitality | 2020 |
| Saltergate Mews Management Co. Limited | Households | 1987 |
| SAP Hairdressing Limited | Other services | 2010 |
| Sarah B Dawson Limited | Professional & scientific | 2010 |
| Sarah Chisem Podiatry Ltd | Health & social care | 2023 |
| Saysike Limited | Information & communication | 2021 |
| Scamp Creative Ltd | Professional & scientific | 2019 |
| Scansys UK Ltd | Information & communication | 2015 |
| Scar Properties LLP | | 2005 |
| Scarlet Dragon Ltd | Real estate | 2020 |
| School Colours Direct Limited | Extraterritorial | 2007 |
| School Colours Limited | Extraterritorial | 1986 |
| Scotton Classic Cars LLP | | 2017 |
| Scotton Garage Limited | Wholesale & retail | 2007 |
| Scotton Motorcycles Limited | Wholesale & retail | 2022 |
| Scotton Tree Care LLP | | 2026 |
| Screen Over Being Limited | Professional & scientific | 2015 |
| Scriven Green Food Consultants Limited | Professional & scientific | 2018 |
| Scriven Park Estates Limited | Financial services | 2017 |
| Scriven Park Pre-School | Education | 2010 |
| SD Interiors (LS) Limited | Construction | 2019 |
| SD Properties LS Limited | Real estate | 2023 |
| Seadragon Studios Limited | Information & communication | 2003 |
| SEB Consultancy Ltd | Real estate | 2025 |
| Sell My Prestige Car Limited | Wholesale & retail | 2015 |
| Sensors for Safety Limited | Administrative & support | 2016 |
| Sheer Bliss Ltd | Wholesale & retail | 2012 |
| Shelley J Whitehead Limited | Other services | 2017 |
| Shepherds Court Scotton Management Company Limited | Households | 2016 |
| Shipton Consulting Limited | Information & communication | 2025 |
| Showtime Fabrics Limited | Wholesale & retail | 2005 |
| Signed by Neha Limited | Administrative & support | 2018 |