| RSL Equity Limited | Professional & scientific | 2026 |
| Rtechnologies Ltd | Financial services | 2021 |
| RTP Staffing Solutions Ltd | Health & social care | 2026 |
| Ruawa Soft Ltd | Information & communication | 2023 |
| Rubencarrollart Ltd | Arts & recreation | 2022 |
| Rubinette Smtvly Ltd | Wholesale & retail | 2025 |
| Rubyprotogenstudio Ltd | Arts & recreation | 2025 |
| Rueelighting Co., Ltd | Manufacturing | 2025 |
| Ruetine Health Ltd | Wholesale & retail | 2026 |
| Rugby Groundworks & Construction Limited | Construction | 2019 |
| RUI Bear Ltd | Wholesale & retail | 2025 |
| Ruifeng International Trading Co., Ltd | Wholesale & retail | 2025 |
| Ruisheng Technology Co., Ltd. | Wholesale & retail | 2025 |
| Ruizi Ltd | Wholesale & retail | 2025 |
| Ruizi Technology Ltd | Manufacturing | 2025 |
| Run in Security Ltd. | Administrative & support | 2015 |
| RUN4 Easyteaching Limited | Education | 2012 |
| Runhe Medical Ltd | Manufacturing | 2025 |
| Runhood Power Ltd | Manufacturing | 2023 |
| Runnin Import and Export Co., Ltd | Administrative & support | 2015 |
| Runpreneur Limited | Health & social care | 2018 |
| Runtosun Ltd | Wholesale & retail | 2025 |
| Runweld Tech Co., Ltd. | Administrative & support | 2020 |
| Runyaya Ltd | Wholesale & retail | 2024 |
| Runyu Ltd | Wholesale & retail | 2025 |
| Ruocheng Co., Ltd | Arts & recreation | 2025 |
| Rural Initiatives Tackling Abuse (Rita) CIC | Professional & scientific | 2025 |
| Rural People Limited | Wholesale & retail | 2025 |
| Rush Global Ltd | Wholesale & retail | 2021 |
| Rushdigital Services Limited | Information & communication | 2025 |
| Rushlinks Global Ltd | Information & communication | 2025 |
| Russell Apparel Ltd | Wholesale & retail | 2025 |
| Russell Dyson Ltd | Manufacturing | 2014 |
| Ruster Holding LP | | 2021 |
| Ruvex Ltd | Administrative & support | 2025 |
| Ruwah Ltd | Professional & scientific | 2022 |
| Rworld International Ltd | Wholesale & retail | 2022 |
| RX Relief Ltd | Health & social care | 2024 |
| RXB Ltd | Wholesale & retail | 2026 |
| Ryah Ltd | Wholesale & retail | 2026 |
| Ryan Lewis Roberts Limited | Extraterritorial | 2023 |
| Ryandell Construction Services Ltd | Construction | 2023 |
| Rybay's Limited | Wholesale & retail | 2024 |
| Rychic Ltd | Extraterritorial | 2024 |
| Rycoo Ltd | Extraterritorial | 2024 |
| Ryeti Mart Ltd | Wholesale & retail | 2025 |
| Ryley Isaac Ltd | Professional & scientific | 2023 |
| Rynal Labs Ltd | Information & communication | 2025 |
| RYZEN5600 Limited | Wholesale & retail | 2026 |
| RYZEN9950X3D Limited | Wholesale & retail | 2026 |
| RZ Oasis Ltd | Wholesale & retail | 2025 |
| Rzcoo Ltd | Extraterritorial | 2024 |
| S &T Home Services Ltd | Construction | 2026 |
| S Infinity Ltd | Health & social care | 2023 |
| S Morris Consultancy Ltd | Professional & scientific | 2016 |
| S Shoporia Ltd | Wholesale & retail | 2025 |
| S&J Apparel Ltd | Wholesale & retail | 2026 |
| S&J's Properties Ltd | Real estate | 2023 |
| S&K Realty Ltd | Information & communication | 2022 |
| S&M Fashion House Ltd | Other services | 2025 |
| S-Rx Services Ltd | Professional & scientific | 2018 |
| S-Swim Ltd | Education | 2022 |
| S.H.R.M Tax Advisors & Accountants Limited | Professional & scientific | 2025 |
| S.O.S. Electrical Luton Limited | Construction | 2014 |
| S.R.U.B Properties Ltd | Real estate | 2023 |
| S.S. Tax House Ltd | Professional & scientific | 2025 |
| S.T Finance Company Limited | Professional & scientific | 2010 |
| SA Bespoke Products Ltd | Manufacturing | 2023 |
| SA Global Enterprises Limited | Wholesale & retail | 2026 |
| SA Security Services Ltd | Administrative & support | 2025 |
| Saasphere Ltd | Information & communication | 2025 |
| SAB Ecommerce Limited | Wholesale & retail | 2025 |
| Sabohitraders Limited | Wholesale & retail | 2024 |
| Sacred House Productions Ltd | Administrative & support | 2019 |
| Sacred Spark Ltd | Wholesale & retail | 2025 |
| Sadik Cargo Limited | Wholesale & retail | 2020 |
| Safe Buy Stores Limited | Wholesale & retail | 2023 |
| Safe Conduct Limited | Public administration | 2020 |
| Safe Living Care Services Ltd | Administrative & support | 2026 |
| Safe Ride Online Limited | Information & communication | 2026 |
| Safehouse XL Limited | Real estate | 2024 |
| Safepoint Financial Ltd | Wholesale & retail | 2025 |
| Safesale Group Ltd | Information & communication | 2025 |
| Safety Check Group UK Limited | Construction | 2024 |
| Saffana Limited | Professional & scientific | 2023 |
| Saffrons Decor Limited | Wholesale & retail | 2020 |
| Safi Coffee CIC | Wholesale & retail | 2019 |
| Sagtau Capital Limited | Information & communication | 2019 |
| Sahand Aria Shahr Ltd | Professional & scientific | 2025 |
| SAI Trend Limited | Wholesale & retail | 2023 |
| Saiban Co., Ltd | Wholesale & retail | 2023 |
| Saibopengkezf Co., Ltd | Wholesale & retail | 2025 |
| Sail Sailing Co., Ltd | Wholesale & retail | 2025 |
| Sailisizf Co., Ltd | Wholesale & retail | 2025 |
| Saint Martin Company LLP | | 2013 |
| Saintella Ltd | Manufacturing | 2025 |
| Saints Property Consultants Ltd | Professional & scientific | 2020 |
| Sajid Sarwar Limited | Other services | 2025 |
| Sakura Beauty Dream Co., Ltd. | Wholesale & retail | 2025 |
| Sakura London Label Limited | Wholesale & retail | 2026 |