| Smart Bodyshop Solutions (Cornwall) Ltd | Wholesale & retail | 2022 |
| Smart Bodyshop Solutions (Group) Ltd | Administrative & support | 2023 |
| Smart Bodyshop Solutions (Heathrow) Ltd | Wholesale & retail | 2024 |
| Smart Bodyshop Solutions (Peterborough) Ltd | Wholesale & retail | 2023 |
| Smart Bodyshop Solutions (Reading) Ltd | Wholesale & retail | 2023 |
| Smart Bodyshop Solutions (Scunthorpe) Ltd | Wholesale & retail | 2023 |
| Smart Bodyshop Solutions (Swansea) Ltd | Wholesale & retail | 2024 |
| Smart Holdings (Salop) Ltd | Professional & scientific | 2022 |
| Smart Logistics Training Limited | Education | 2017 |
| Smart Solutions Tech Ltd | Wholesale & retail | 2020 |
| Smash Operations Limited | Hospitality | 2020 |
| Smith & Laine Property Ltd | Real estate | 2025 |
| Smithambridge Management Limited | Households | 1990 |
| Smiths Medical Group Ltd | Households | 2025 |
| Smithyvans Ltd | Professional & scientific | 2020 |
| SML123 Ltd | Administrative & support | 2015 |
| SMW Building Solutions Ltd | Construction | 2019 |
| Snak Restaurants Ltd | Hospitality | 2020 |
| Snip Systems Limited | Information & communication | 1999 |
| Snuffles Wood Ltd | Agriculture & fishing | 2023 |
| SOC Communities Foundation CIC | Education | 2019 |
| Social Scanner Ltd | Wholesale & retail | 2023 |
| Socratavia Limited | Information & communication | 2023 |
| SOL Maintenance and Property Services Ltd | Real estate | 2024 |
| Solar Power Solutions Ltd | Construction | 2023 |
| Soller Care Ltd | Health & social care | 2025 |
| Soller Tanning Ltd | Other services | 2025 |
| Something Special (Kingswinford) Ltd | Wholesale & retail | 2009 |
| Sommai Thai Restaurant Limited | Hospitality | 2022 |
| Sorella Wellness Ltd | Other services | 2026 |
| Sorted Direct Mail Holdings Limited | Financial services | 2016 |
| Sorted Print Management Limited | Manufacturing | 2018 |
| Sorted Print Services Limited | Manufacturing | 2023 |
| SOS Components Ltd | Wholesale & retail | 2019 |
| SOS Property Ltd | Financial services | 2026 |
| Sound Software Ltd | Information & communication | 2009 |
| South Quays Limited | Information & communication | 2010 |
| Southaulage Ltd | Transport & logistics | 2025 |
| Southwell Education Limited | Education | 2024 |
| Spa Electrical Contractors Limited | Construction | 2002 |
| Spa Motorcycles Cheltenham Limited | Wholesale & retail | 2015 |
| Spa Promotions Ltd | Wholesale & retail | 2022 |
| Sparkly M'S Cleaning Services Ltd | Administrative & support | 2020 |
| Sparna Ventures Ltd | Wholesale & retail | 2024 |
| Special Projects (C41) Ltd | Information & communication | 2007 |
| Specialist Paving Limited | Other services | 2024 |
| Spectrum External Cleaning Ltd | Administrative & support | 2025 |
| Speed Data Ltd | Construction | 2007 |
| Sports Dog Limited | Agriculture & fishing | 2018 |
| Spray Smart Sale Smart Ltd | Wholesale & retail | 2020 |
| Spread Properties Ltd | Households | 2024 |
| Sproson Developments Ltd | Construction | 2022 |
| SQUIRES2KINGS Ltd | Households | 2023 |
| SRG Utilities Ltd | Construction | 2024 |
| SS Tattoos Limited | Arts & recreation | 2013 |
| SSA Automotive Repairs Ltd | Wholesale & retail | 2022 |
| SSA Performance Ltd | Wholesale & retail | 2023 |
| ST Philips Group Ltd | Financial services | 2022 |
| ST Philips Homes (Belbroughton Management) Ltd | Households | 2020 |
| ST Philips Homes (Belbroughton) Limited | Real estate | 2018 |
| ST Philips Homes (Burton Joyce Management) Ltd | Households | 2020 |
| ST Philips Homes (Burton Joyce) Limited | Real estate | 2018 |
| ST Philips Homes (Courthaulds Management) Ltd | Households | 2020 |
| ST Philips Homes (Courthaulds) Limited | Real estate | 2018 |
| ST Philips Homes (Cromwell) Limited | Real estate | 2020 |
| ST Philips Homes (Dove Lane) Ltd | Real estate | 2025 |
| ST Philips Homes (Eccleshall) Ltd | Real estate | 2023 |
| ST Philips Homes (Hope Road) Ltd | Real estate | 2025 |
| ST Philips Homes (Webheath Central Phase 1A) Ltd | Construction | 2025 |
| ST Philips Homes Construction Limited | Construction | 2023 |
| ST Philips Homes Ltd | Real estate | 2017 |
| ST Philips Infrastructure Ltd | Real estate | 2017 |
| ST Philips Investments Ltd | Real estate | 2017 |
| ST Philips Land (Alvechurch) Limited | Real estate | 2018 |
| ST Philips Land (Dordon) Ltd | Real estate | 2022 |
| ST Philips Land (Fairfield) Limited | Real estate | 2026 |
| ST Philips Land (Market Harborough) Ltd | Real estate | 2019 |
| ST Philips Land Ltd | Real estate | 2017 |
| ST Philips Ltd | Real estate | 2017 |
| ST Teresa Ltd | Health & social care | 2008 |
| STA Logistics Limited | Transport & logistics | 2010 |
| Stac Services Ltd | Administrative & support | 2021 |
| Stallings Lane Motors Limited | Wholesale & retail | 2009 |
| Star Car Panels Limited | Wholesale & retail | 2006 |
| Starlight Campers Limited | Manufacturing | 2011 |
| Starlight Tyre Garage Ltd | Wholesale & retail | 2026 |
| Stay DRY Limited | Administrative & support | 2012 |
| Steel Roof Sheets Limited | Extraterritorial | 2009 |
| Steele Electrical Installations Ltd | Construction | 2026 |
| Steele Haberdashery Ltd | Wholesale & retail | 2023 |
| Stefanosk Ltd | Real estate | 2024 |
| Stephanie Margaret Wilson Ltd | Information & communication | 2016 |
| Sterling Heating Limited | Construction | 2004 |
| Steve Foster Leisure Services Limited | Manufacturing | 2015 |
| Steve Hatton Installs Limited | Construction | 2012 |
| Stikon Limited | Wholesale & retail | 2017 |
| Stiltz (Holdings) Limited | Professional & scientific | 2015 |
| Stiltz Group Holdings Limited | Financial services | 2017 |
| Stiltz Limited | Manufacturing | 2010 |
| Stimela Associates Holdings Limited | Financial services | 2021 |