| Pyne Estates Limited | Real estate | 1999 |
| Pyrates the Golden AGE Limited | Manufacturing | 2022 |
| Quantum Heritage Limited | Manufacturing | 2001 |
| Quarry Heights Residents Ltd | Households | 2013 |
| Quay Dental Limited | Health & social care | 2023 |
| Quay Garage Company,Limited | Wholesale & retail | 1914 |
| Quelque Chose Limited | Manufacturing | 2016 |
| Questpart Limited | Transport & logistics | 1988 |
| R a Miller Carpentry Ltd | Manufacturing | 2021 |
| R B Buildings (SW) Limited | Construction | 2010 |
| R. F. Drylining Limited | Construction | 2001 |
| R. W. Bawden Ltd | Wholesale & retail | 2018 |
| Raleigh Slip Management Limited | Households | 2024 |
| Raleigh Street (Dartmouth) Management Limited | Households | 2013 |
| Rates Savings Limited | Professional & scientific | 2013 |
| RAW PR and Marketing Limited | Hospitality | 2015 |
| Reaction App Ltd | Information & communication | 2026 |
| Rebel Totnes Limited | Wholesale & retail | 2005 |
| Recovery Xchange Ltd | Administrative & support | 2025 |
| Recruitify Limited | Administrative & support | 2018 |
| Red Herring Estates Limited | Real estate | 2016 |
| Red Herring Shoes Limited | Wholesale & retail | 2000 |
| Redwood Drive (Loddiswell) Limited | Real estate | 2018 |
| Reflectique Limited | Manufacturing | 2024 |
| REG & Moll Limited | Real estate | 2024 |
| Relix Ltd | Real estate | 2020 |
| Retention Funding Ltd | Information & communication | 2019 |
| Retrospective History Ltd. | Information & communication | 2021 |
| Rhool Ltd | Wholesale & retail | 2020 |
| Richard Gubbay Chiropractic Limited | Health & social care | 2002 |
| Richcraft Maintenance Limited | Construction | 2025 |
| Riddell & Associates Ltd | Construction | 2018 |
| Ridgeway Rents Limited | Real estate | 2002 |
| Riptide Marine Ltd | Manufacturing | 2019 |
| Riverside Management (Kingsbridge) Limited | Real estate | 1970 |
| RJH Carpentry and Building Ltd | Construction | 2025 |
| RLO Development Limited | Manufacturing | 2002 |
| RLS Search Ltd | Administrative & support | 2014 |
| RNA Golf Limited | Wholesale & retail | 2013 |
| Roberts Health Ltd | Health & social care | 2016 |
| Robin Knight Property Ltd | Real estate | 2017 |
| Robins Park Management Limited | Households | 2017 |
| Robinson Deux Ltd | Information & communication | 2025 |
| ROBOTS4FOREX Ltd | Information & communication | 2023 |
| Robson Plant Services Ltd | Construction | 2025 |
| Roger Lamble Limited | Construction | 2002 |
| Rope Strap Ltd | Wholesale & retail | 2025 |
| Rosalind Walker Coaching Limited | Professional & scientific | 2021 |
| Rounded Ltd | Wholesale & retail | 2024 |
| Rover.T Properties Ltd | Construction | 2019 |
| Rumsey of Sandbanks Holiday Homes Limited | Administrative & support | 2023 |
| Ruth Mason Ltd | Public administration | 2014 |
| RW & KA Holdings Limited | Financial services | 2023 |
| RW & KA Land Limited | Real estate | 2025 |
| S & K Watson Ltd | Hospitality | 2013 |
| S M V R Limited | Wholesale & retail | 2015 |
| Sada Group Ltd | Other services | 2025 |
| Safari and Beach Travel Limited | Administrative & support | 2009 |
| Saffron Plumbing and Heating Limited | Construction | 2013 |
| Sails (Dartmouth) Management Company Limited | Extraterritorial | 2014 |
| Salar Developments Limited | Professional & scientific | 1988 |
| Salcombe Breeze Ltd | Hospitality | 2022 |
| Salcombe Brokerage Ltd | Financial services | 2015 |
| Salcombe Dinghy Sailing Limited | Arts & recreation | 2014 |
| Salcombe Live Festival CIC | Arts & recreation | 2021 |
| Salcombe Marine Engineering Ltd | Manufacturing | 2017 |
| Salcombe Marine Insurance Services Limited | Extraterritorial | 2007 |
| Salcombe Rugby Football and Athletic Club Limited | Arts & recreation | 2009 |
| Salcombe Sea Wear Ltd | Wholesale & retail | 2021 |
| Salcombe Taxi Co Ltd | Transport & logistics | 2025 |
| Saltstone Boats Ltd | Wholesale & retail | 2016 |
| Salty Stays Ltd | Real estate | 2026 |
| Samina Support Services SW LLP | | 2017 |
| Samphire Foods Ltd. | Manufacturing | 2006 |
| Sample Media Marketing Ltd | Professional & scientific | 2025 |
| Sara Stone Bookkeeping and Payroll Services Limited | Professional & scientific | 2003 |
| Saviour (BE Your Own Hero) Limited | Manufacturing | 2024 |
| SB Busybee Limited | Wholesale & retail | 2024 |
| SBL Decorating Ltd | Construction | 2022 |
| Scholars Walk (NO.2) Management Company Limited | Households | 2003 |
| Scholars Walk Kingsbridge Management Company Limited | Households | 2003 |
| Scoble Basin Limited | Transport & logistics | 2016 |
| Scoble Road Limited | Households | 2006 |
| Scope Works Consulting Ltd | Professional & scientific | 2022 |
| Scruffy Dog Design Ltd | Professional & scientific | 2026 |
| Sea Chest Limited | Hospitality | 1998 |
| Sea Kayak Salcombe Limited | Arts & recreation | 2002 |
| Seadream Education CIC | Education | 2017 |
| Selworthy Vets Ltd | Professional & scientific | 2017 |
| Severn Marine Geoconsulting Ltd | Professional & scientific | 2024 |
| Shapers Toning Salon Ltd | Health & social care | 2009 |
| Shawn Hutchings Building Ltd | Construction | 2006 |
| SHE Flies CIC | Wholesale & retail | 2020 |
| SHE Flies Enterprise Ltd | Professional & scientific | 2023 |
| Shellbar Limited | Administrative & support | 1996 |
| Shilling & Ball Ltd | Hospitality | 2024 |
| Shippen Legal Services Limited | Professional & scientific | 2022 |
| Shore Defence Ltd | Construction | 2020 |
| Shree Services Limited | Wholesale & retail | 2018 |
| Shutter Stuff LP | | 2016 |