| Rosalyn Bearing Co., Ltd | Extraterritorial | 2021 |
| Rose Morning Ltd | Wholesale & retail | 2024 |
| Roseville (Wellingborough) Limited | Construction | 2023 |
| Roseville Group Holdings Ltd | Financial services | 2022 |
| Ross Contractors Ltd. | Construction | 2014 |
| Rosy Cherry Limited | Wholesale & retail | 2025 |
| Roundbox Creative Ltd | Professional & scientific | 2009 |
| Rowan and Rose Limited | Professional & scientific | 2025 |
| Roxhill (Peterborough Infrastructure) Limited | Construction | 2010 |
| Roxhill (Peterborough) Limited | Real estate | 2010 |
| Roxhill (Tilbury) Limited | Real estate | 2012 |
| Roxhill Developments Group Limited | Construction | 2010 |
| Roxhill Developments Limited | Construction | 2009 |
| Roy's Food Ltd | Hospitality | 2023 |
| Royalle Cool Ltd | Manufacturing | 2024 |
| Royi Electronics Co., Limited | Wholesale & retail | 2024 |
| RSP Underground Services Ltd | Construction | 2024 |
| RST Electric Limited | Administrative & support | 2021 |
| Rugby Farmers Mart Limited | Wholesale & retail | 2011 |
| Rugby Road Freehold Management Ltd | Real estate | 2018 |
| Ruian Hendin Materials Limited | Administrative & support | 2023 |
| Rukin Limited | Administrative & support | 2022 |
| Rumours Beauty Products Limited | Other services | 2011 |
| Rungrot Ltd | Hospitality | 2019 |
| Running Products Co., Ltd | Extraterritorial | 2017 |
| Runto Industry Co., Ltd | Administrative & support | 2023 |
| Runzi Chemical International Co., Ltd | Wholesale & retail | 2012 |
| Rupert Quin Surveyors Ltd | Extraterritorial | 2021 |
| Rural Industries Co., Ltd | Administrative & support | 2014 |
| RV Sport & Education Limited | Education | 2022 |
| RY Household Ltd. | Extraterritorial | 2018 |
| RYE Meadow Estates Management Limited | Households | 1997 |
| S K Wilson Group Limited | Administrative & support | 2021 |
| S N Machin Limited | Information & communication | 2020 |
| S Pro Management Limited | Real estate | 2024 |
| S Sarkar Consulting Ltd | Professional & scientific | 2024 |
| S&C Textile Tech Ltd | Extraterritorial | 2017 |
| S.H. & D.Smith Limited | Wholesale & retail | 1953 |
| S.J. Ainsworth Consultancy Ltd. | Professional & scientific | 1993 |
| S.M.V. (UK) Limited | Extraterritorial | 1998 |
| Sabin and Ball Heating and Plumbing Ltd | Construction | 2023 |
| Sabron Properties Limited | Real estate | 2023 |
| Safe Strike Ltd | Manufacturing | 2012 |
| Safeworks (UK) Construction Limited | Construction | 2013 |
| Sailaulond and Vonceron (U.K) Limited | Extraterritorial | 2011 |
| Sailing Global Limited | Administrative & support | 2026 |
| Sailing Industry Limited | Administrative & support | 2026 |
| Salidomi Chemical Limited | Administrative & support | 2025 |
| Salisbury&Talbot Ltd | Hospitality | 2026 |
| Salt + Bear Pilates Ltd | Arts & recreation | 2022 |
| Salube (U.K) Petrochemical Co., Ltd. | Extraterritorial | 2018 |
| Salvere Health & Wellbeing Ltd | Education | 2024 |
| Salveson FOX Limited | Professional & scientific | 1991 |
| Samantha Grey Limited | Professional & scientific | 2020 |
| Sandrock International Trading Co., Ltd | Administrative & support | 2020 |
| Sandwiches Sandwiches Limited | Hospitality | 2025 |
| Sapphire Laundry Rentals Limited | Administrative & support | 2020 |
| Sapphire Laundry Systems Ltd | Wholesale & retail | 2019 |
| Sapphire Lending Ltd | Financial services | 2014 |
| Sapphire Trade Warehouse Limited | Wholesale & retail | 2024 |
| Sarah Cooke School of Dance Ltd. | Arts & recreation | 2002 |
| Sarah Griffiths Ltd | Manufacturing | 2023 |
| Sarah Harvey Holdings Limited | Professional & scientific | 2012 |
| Sarah Harvey Limited | Administrative & support | 2008 |
| Sarah Knapper Ltd | Professional & scientific | 2024 |
| Sarah O'Leary Consultants Limited | Professional & scientific | 2016 |
| Sarah O'Leary Lettings Ltd | Real estate | 2018 |
| Sarah Thomson Ltd. | Extraterritorial | 2016 |
| Sasahivi Limited | Education | 2012 |
| Satis Products Co., Ltd | Extraterritorial | 2017 |
| SBS Coventry Ltd | Other services | 2013 |
| SBS Midlands Ltd | Other services | 2017 |
| Scientia Partners Ltd | Professional & scientific | 2023 |
| SCX Trading Limited | Wholesale & retail | 2026 |
| Sea Waves Limited | Professional & scientific | 2006 |
| Seagor Group Co Ltd | Manufacturing | 2019 |
| Seahorse Process Engineering Limited | Wholesale & retail | 2007 |
| Seltech Engineering Products Limited | Wholesale & retail | 1992 |
| Semicorex Advanced Material Technology Co., Ltd | Administrative & support | 2023 |
| Semishine Limited | Extraterritorial | 2018 |
| Senlaw Ltd | Professional & scientific | 2024 |
| Sentinel HS Ltd | Administrative & support | 2022 |
| Sequoia Seeds Ltd | Real estate | 2019 |
| Serial Platform Limited | Information & communication | 2016 |
| Serious Style Limited | Other services | 2012 |
| Servia Limited | Other services | 2013 |
| Services Fusion Ltd | Professional & scientific | 2018 |
| Seterpower Electronic Co., Ltd | Administrative & support | 2019 |
| Seyel Ltd | Agriculture & fishing | 2011 |
| Shakespeares Shepherd Huts Limited | Construction | 2018 |
| Shakui Trade Co., Ltd | Administrative & support | 2021 |
| Shandong Greentree Trade Ltd | Extraterritorial | 2015 |
| Shandong Shenzhou Chemical Co., Ltd | Administrative & support | 2026 |
| Shanghai Genute (UK) Co., Ltd | Administrative & support | 2020 |
| Shanghai Juren Trading Co., Ltd | Administrative & support | 2024 |
| Shanghai Longhua Construction Machinery Ltd | Administrative & support | 2023 |
| Shanghai Longji Precision Industry Co., Ltd | Administrative & support | 2010 |
| Shanghai Ruixuan Yuan Shipping Co., Ltd | Administrative & support | 2024 |
| Shanghai Sanli International Trading Co., Ltd | Administrative & support | 2024 |
| Shanghai Tokin Industry Co., Ltd | Extraterritorial | 2015 |