| Redsikes Eggs Limited | Agriculture & fishing | 2003 |
| Redstart Renewables Limited | Energy | 2014 |
| Redsteads Farm Cottages Ltd | Construction | 2022 |
| Reeth Consulting Ltd | Administrative & support | 2016 |
| Regenerative Accounting Ltd | Professional & scientific | 2011 |
| Relationship Health Matters CIC | Education | 2022 |
| Relay Team Ltd | Professional & scientific | 2014 |
| Remote Technology Limited | Professional & scientific | 2009 |
| Renata LAB Ltd | Professional & scientific | 2026 |
| Renstone Properties Ltd | Real estate | 2016 |
| Rescuetec Ltd | Professional & scientific | 2018 |
| Reshapedesign Ltd | Professional & scientific | 2026 |
| Resilium UK Limited | Information & communication | 2015 |
| Resolveiq Platform Ltd Ltd | Information & communication | 2026 |
| Retiramount Ltd | Administrative & support | 2024 |
| Revenue Pipeline Partners Limited | Professional & scientific | 2009 |
| Revolutionary Concepts Ltd | Professional & scientific | 2022 |
| Rewired Brand Ltd | Wholesale & retail | 2023 |
| Richard Bell Electrical Limited | Construction | 2011 |
| Rigged and Ready Ltd | Wholesale & retail | 2009 |
| Riggs Cafe Ltd | Hospitality | 2020 |
| RIGHT2WORK C.I.C. | Hospitality | 2011 |
| Rin's Coffee Ltd | Manufacturing | 2015 |
| RLT Civils Limited | Construction | 2011 |
| ROB Bell Fencing Limited | Construction | 2015 |
| ROB Kelly Consulting Limited | Professional & scientific | 2023 |
| Robcat Health Care Ltd | Health & social care | 2018 |
| Roberts Reizins Consulting Limited | Professional & scientific | 2025 |
| Rockrose Property Limited | Real estate | 2016 |
| Roeburn House Management Limited | Households | 2018 |
| Roger J Wilson Associates Limited | Administrative & support | 2012 |
| Roger Waddington Ltd | Administrative & support | 2023 |
| Rope Access and Inspection Limited | Administrative & support | 2018 |
| Rotosystems Limited | Wholesale & retail | 2014 |
| ROW Lane Ltd | Professional & scientific | 2025 |
| Rowan Ranner Communication Pathways Speech and Language Therapy Limited | Health & social care | 2025 |
| RRC Property Ltd | Real estate | 2021 |
| RUBYS166 Takeaway Limited | Hospitality | 2026 |
| Running JO Ltd | Education | 2021 |
| Rupicapra Limited | Information & communication | 2017 |
| Ruskins Bar Limited | Hospitality | 2019 |
| Russ Andrews Accessories Ltd. | Manufacturing | 1985 |
| Ruth FOX Ltd | Hospitality | 2019 |
| Ruyi Takeaway Limited | Hospitality | 2021 |
| Rwenzori Coffee Company Ltd | Wholesale & retail | 2018 |
| RX3 Hydro Gatebeck Limited | Energy | 2014 |
| Rydal Hydro Limited | Energy | 2014 |
| S a & a S Walling Ltd | Wholesale & retail | 2003 |
| S a Plant Ltd | Agriculture & fishing | 2024 |
| S J Bennett Engineering Limited | Manufacturing | 2000 |
| S J Campers Limited | Manufacturing | 2016 |
| S W Plumbing & Heating (Kendal) Ltd | Construction | 2015 |
| S-Runners Club CIC | Arts & recreation | 2026 |
| Safe Zone Systems Ltd | Manufacturing | 2025 |
| Safeci Group Ltd | Information & communication | 2026 |
| Safestream Water and Air Ltd | Financial services | 2022 |
| SAM Sykes Ltd | Education | 2009 |
| Samsara Custom Tattoo Limited | Other services | 2017 |
| SAN Digital Limited | Information & communication | 2020 |
| SANCAK2000 Limited | Other services | 2024 |
| Sandylands Fish & Chips Limited | Wholesale & retail | 2012 |
| Santarino Kirkland Ltd | Hospitality | 2023 |
| Santini Holdings Limited | Financial services | 2017 |
| Santini Properties Limited | Real estate | 2016 |
| Saphr Consulting Limited | Information & communication | 2007 |
| Sapore Kendal Limited | Hospitality | 2021 |
| Sapphire Boutique 35 Ltd | Other services | 2024 |
| Sarah Jones Limited | Other services | 2015 |
| Sarah Risley Ltd | Information & communication | 2023 |
| SAS Catering Services Limited | Hospitality | 2025 |
| SBG Construction Limited | Construction | 2009 |
| SC Callander Limited | Wholesale & retail | 2025 |
| Scandale Hydro Limited | Energy | 2014 |
| Scern Technology Ltd | Information & communication | 2023 |
| Schwan-Stabilo Outdoor UK Ltd | Wholesale & retail | 2023 |
| Sclakes Taxis Ltd | Wholesale & retail | 2023 |
| Sco'Pic Ltd | Information & communication | 2017 |
| Scoop Choc Ices Limited | Manufacturing | 2003 |
| Scratch Creative Limited | Manufacturing | 2011 |
| Screenworld Limited | Professional & scientific | 1999 |
| SDW Holdings Limited | Financial services | 2016 |
| Sea Kayaking Company Limited | Arts & recreation | 2025 |
| Searchvista Limited | Professional & scientific | 2011 |
| SEB Services Ltd | Transport & logistics | 2026 |
| Seb's CAB Ltd | Transport & logistics | 2026 |
| Second Style Limited | Wholesale & retail | 2026 |
| Secura Group Ltd | Professional & scientific | 2008 |
| Sedgwick Mews Leasehold Management Company Limited | Households | 2013 |
| SEE Events Limited | Arts & recreation | 2009 |
| Semper Eximius Management Limited | Professional & scientific | 2013 |
| Serpentine Road Management (Kendal) Limited | Hospitality | 2011 |
| Service With a Smile Training Ltd | Other services | 2025 |
| SGN Fire & Security Limited | Other services | 1989 |
| Shaw White Property Development Limited | Construction | 2024 |
| Shawend Ltd | Professional & scientific | 2021 |
| Shelaba Limited | Financial services | 2003 |
| Shelley Knowles Hairdressing Limited | Other services | 2005 |
| Shelter Stone Medical and Rescue Services Limited | Health & social care | 2025 |
| Sheridans Bars Limited Limited | Hospitality | 2025 |
| Shindiggery Productions Ltd | Professional & scientific | 2025 |