| S & H Gibbons Consultancy Ltd | Construction | 2018 |
| S & L Rail Ltd | Professional & scientific | 2014 |
| S & S Business Consultants Limited | Professional & scientific | 2000 |
| S & S Carpentry Group Ltd | Construction | 2022 |
| S & S Properties (Needham Market) Limited | Real estate | 2011 |
| S & T Installations Limited | Manufacturing | 2016 |
| S a UK Property Ltd | Financial services | 2022 |
| S and L Flat Roofing Ltd | Construction | 2022 |
| S B Building & Plumbing Limited | Construction | 2006 |
| S B Electrical Services and Maintenance Ltd | Construction | 2025 |
| S C Brightwell Agri Ltd | Agriculture & fishing | 2014 |
| S Challis Landscaping & Brickwork Ltd | Construction | 2010 |
| S Chick Investigations Limited | Professional & scientific | 2019 |
| S D G Financial Limited | Financial services | 2015 |
| S D Trading UK (Ipswich) Limited | Wholesale & retail | 2011 |
| S Diaper Contracts Limited | Construction | 2005 |
| S Huma Qureshi Ltd | Health & social care | 2014 |
| S J Fashions London Limited | Wholesale & retail | 2018 |
| S J Morling Ltd | Construction | 2018 |
| S Lewis TM Limited | Administrative & support | 2019 |
| S Long Plumbing & Heating Ltd | Construction | 2023 |
| S M Driver Roofing Ltd | Construction | 2018 |
| S M Electrical Contractors Ltd | Construction | 2019 |
| S M Ibryam Ltd | Transport & logistics | 2021 |
| S M S Stainless Limited | Manufacturing | 2005 |
| S M T T Limited | Health & social care | 2014 |
| S M Westgate Carpentry & Joinery Limited | Construction | 2016 |
| S Miah Services Ltd | Professional & scientific | 2025 |
| S N Anaesthetists Ltd | Health & social care | 2014 |
| S Newman Cars Limited | Wholesale & retail | 2003 |
| S O Store Ltd | Wholesale & retail | 2023 |
| S P M Brickwork Limited | Construction | 2009 |
| S R Calver (Building Contractor) Limited | Construction | 2006 |
| S Todd Recruitment Ltd | Administrative & support | 2015 |
| S&B Plumbing Ltd | Construction | 2022 |
| S&B Properties Development Ltd | Real estate | 2026 |
| S&C Interim Solutions Ltd | Professional & scientific | 2023 |
| S&D Signature Properties Ltd | Real estate | 2019 |
| S&G Metals Limited | Wholesale & retail | 2026 |
| S&I Wellness Limited | Wholesale & retail | 2025 |
| S&J Sahota Properties Ltd | Real estate | 2021 |
| S&K SPV Limited | Real estate | 2022 |
| S&M Trans Limited | Transport & logistics | 2017 |
| S&P UK Ventilation Systems Ltd. | Manufacturing | 1984 |
| S&R Wedding Stylists Limited | Hospitality | 2023 |
| S&Sr Consultancy Ltd | Professional & scientific | 2024 |
| S&T Retail Ltd | Wholesale & retail | 2025 |
| S. C. Brader Plumbing & Heating Ltd | Construction | 2012 |
| S. Cowle Electrical Limited | Construction | 1975 |
| S.A. Wilson Ltd. | Wholesale & retail | 2019 |
| S.B.S. (Ipswich) Limited | Extraterritorial | 1997 |
| S.B.S. Sales & Services Limited | Wholesale & retail | 1993 |
| S.B.S. Spares Limited | Wholesale & retail | 1958 |
| S.C.H. Supplies Holdings Limited | Financial services | 2019 |
| S.C.H. Supplies Limited | Manufacturing | 1970 |
| S.C.O.P Limited | Administrative & support | 2008 |
| S.C.O.T 2 Limited | Professional & scientific | 2008 |
| S.C.O.T Limited | Administrative & support | 2008 |
| S.Deepa Ltd | Wholesale & retail | 2015 |
| S.Deepa Properties Investment Ltd | Real estate | 2021 |
| S.E.H. (Developments) Limited | Construction | 2000 |
| S.E.H. (Ipswich) Limited | Construction | 1989 |
| S.E.R.C Recycling Limited | Administrative & support | 2015 |
| S.E.R.C Technologies Limited | Administrative & support | 2015 |
| S.E.R.C. Biofuels Limited | Manufacturing | 2016 |
| S.E.R.C. Eco Installations Limited | Manufacturing | 2016 |
| S.E.R.C. Energy Ptfm One Ltd | Administrative & support | 2024 |
| S.E.R.C. Finance Ltd | Administrative & support | 2024 |
| S.E.R.C. Group Limited | Professional & scientific | 2018 |
| S.E.R.C. Holdings UK Ltd | Financial services | 2024 |
| S.F.C. Management (1997) Limited | Administrative & support | 1996 |
| S.G. Ellis Construction Limited | Construction | 1999 |
| S.H.E.Advises Ltd | Professional & scientific | 2016 |
| S.J. Whinney Construction Ltd | Construction | 2003 |
| S.M.Art Build East Ltd | Construction | 2017 |
| S17 Advisory Limited | Professional & scientific | 2024 |
| SA Driving Ltd | Transport & logistics | 2022 |
| Sa&So Ltd | Real estate | 2023 |
| Saab Assets Ltd | Real estate | 2026 |
| Saam Group Ltd | Financial services | 2020 |
| Saam Property Group Ltd | Real estate | 2024 |
| Saam Property Holdings Ltd | Real estate | 2026 |
| Saarav Estates Ltd | Real estate | 2025 |
| SAB (East Anglia) Ltd | Wholesale & retail | 2025 |
| Sabeez Peri Peri Limited | Hospitality | 2024 |
| Saber Tooth 4X4 Ltd | Manufacturing | 2021 |
| Sabin Logistics Ltd | Transport & logistics | 2025 |
| Sable Properties and Interiors Ltd | Construction | 2025 |
| Sabr Properties Ltd | Real estate | 2024 |
| Sabrejet Holdings Limited | Real estate | 2022 |
| SAC Ipswich Ltd | Other services | 2018 |
| Sachin Agile Industries (SAI) Ltd | Hospitality | 2010 |
| Sackers Limited | Water & waste | 1980 |
| Sackers Recycling Limited | Extraterritorial | 2012 |
| Sacred Kraken Tattoo Studio Ltd | Other services | 2020 |
| Sacserv Ltd | Real estate | 2024 |
| Saddymaans Ltd | Wholesale & retail | 2025 |
| Safa Mobile Limited | Hospitality | 2025 |
| Safe & Sound Property Ltd | Real estate | 2023 |
| Safe and Sound Homecare Limited | Other services | 2017 |