| Ecso Property Limited | Real estate | 2022 |
| Edge 2 Detail Holdings Limited | Financial services | 2018 |
| Edge 2 Detail Limited | Manufacturing | 1999 |
| Edwards Plastering Limited | Construction | 2006 |
| EEC Plant & Hire Ltd | Wholesale & retail | 2026 |
| Eesan Ltd | Wholesale & retail | 2023 |
| Ehko Ltd | Wholesale & retail | 2019 |
| Elders Estates Ltd | Real estate | 2012 |
| Electracentre Distribution Limited | Wholesale & retail | 1991 |
| Electracentre Limited | Professional & scientific | 2004 |
| Electro Mechanical Developments Limited | Professional & scientific | 2010 |
| Electro Technical Midlands Ltd | Construction | 2018 |
| ELF Trade Ltd | Wholesale & retail | 2025 |
| Elfcareuk Ltd | Health & social care | 2015 |
| Elite Aesthetics Medical Ltd | Health & social care | 2025 |
| Elite Ceramic Tiling Ltd | Construction | 2004 |
| Elite Construction and RIP OUT Clearance Ltd | Construction | 2026 |
| Elite Hair & Beauty Limited | Other services | 2023 |
| Elite Mechanical Services Limited | Construction | 2019 |
| Elite PUB Holdings Ltd | Hospitality | 2022 |
| Elite Pubs (Eastwood) Ltd | Hospitality | 2025 |
| Elite Pubs (Mablethorpe) Ltd | Hospitality | 2025 |
| Elite Rope Access Ltd | Manufacturing | 2023 |
| Elliotts Automotive Ltd | Wholesale & retail | 2024 |
| Ellis Andrew Plumbing and Heating Ltd | Construction | 2026 |
| Ellis Electrical Consultants Ltd | Construction | 2017 |
| ELM Tree Garage (Nottingham) Limited | Wholesale & retail | 2010 |
| ELM Tree Garage Limited | Real estate | 1980 |
| Elsie Civils Ltd | Construction | 2020 |
| Elvaston Castle Steam Rally | Arts & recreation | 1984 |
| Emcon Industrial Services Limited | Manufacturing | 2001 |
| Emily-Rose Wedding and Events Singer Ltd | Arts & recreation | 2025 |
| Emre Shop Ltd | Wholesale & retail | 2024 |
| EMS24 Ltd | Professional & scientific | 2024 |
| Energised Electrical Contractors Ltd | Construction | 2021 |
| Engineered by RIZ Ltd | Arts & recreation | 2022 |
| Engineered Coaching Ltd | Arts & recreation | 2024 |
| Engineering Design & Build Consultancy Limited | Professional & scientific | 2016 |
| Enhanced Detailing Limited | Administrative & support | 2025 |
| Enhanced Vision Europe Limited | Wholesale & retail | 2006 |
| Enso HR Consultancy Ltd | Information & communication | 2014 |
| Ensure Education Ltd | Professional & scientific | 2018 |
| Entrasite Ltd | Construction | 2023 |
| Environment Lighting Limited | Manufacturing | 2012 |
| Eportalion Limited | Financial services | 2025 |
| Equisio Limited | Professional & scientific | 2013 |
| Erewash Drives Ltd | Construction | 2019 |
| Erewash Partnership (Events) Limited | Arts & recreation | 2018 |
| Erewash Partnership (Managed Workspace) Limited | Real estate | 1998 |
| Erewash Partnership Limited | Administrative & support | 1994 |
| Erewash Patterns Limited | Manufacturing | 2000 |
| Erewash Sound Community Interest Company | Information & communication | 2008 |
| Erewash Valley Golf Club Limited | Arts & recreation | 1910 |
| Erewash Valley Gymnastics Club Ltd | Arts & recreation | 2013 |
| ERO Limited | Construction | 2023 |
| Essential Money Matters Limited | Financial services | 2013 |
| Etiquette Park Management Company Limited | Households | 2022 |
| Eurotruck Midlands Limited | Wholesale & retail | 2004 |
| Everclear Drainage Solutions Ltd | Water & waste | 2025 |
| Everton Global Ltd | Wholesale & retail | 2025 |
| Everwarm and DRY Ltd | Construction | 2024 |
| Evoke Sounds Limited | Information & communication | 2020 |
| Evolution Media Marketing Ltd | Information & communication | 2019 |
| Exceedingly Limited | Transport & logistics | 2017 |
| Exec Spec Limited | Wholesale & retail | 2003 |
| Eyeconnectuk Limited | Administrative & support | 2009 |
| Eyejay Ltd | Wholesale & retail | 2019 |
| Eyetee Network Supplies Limited | Information & communication | 2004 |
| F C Laser Holdings Limited | Professional & scientific | 2016 |
| F F Allsopp Holdings Limited | Manufacturing | 2012 |
| F.F.Allsopp & Co.,Limited | Manufacturing | 1917 |
| FAB Candle Ltd | Manufacturing | 2025 |
| Fastlathe Limited | Construction | 2004 |
| FAY Allison Interior Design Ltd | Professional & scientific | 2026 |
| FC Racing Ltd | Agriculture & fishing | 2026 |
| FDG Business Accounting Limited | Professional & scientific | 2008 |
| FED Interiors Limited | Extraterritorial | 2009 |
| Fellas of Worksop Limited | Other services | 2008 |
| Feras Barbers 1 Ltd | Other services | 2025 |
| Filbert Lone Ltd | Administrative & support | 2023 |
| Financial Inclusion Support Initiative CIC | Information & communication | 2024 |
| Financial Strength Limited | Real estate | 2016 |
| Finch Garden Rooms Limited | Construction | 2018 |
| Finnys Maintenance Services Limited | Wholesale & retail | 2025 |
| Fintech Advisor Limited | Professional & scientific | 2020 |
| Firefox Logistics Ltd | Transport & logistics | 2021 |
| Fisk Electrical Installations Ltd | Construction | 2020 |
| Five Minds Consultancy Limited | Professional & scientific | 2019 |
| Five Star Ilkeston Ltd | Hospitality | 2019 |
| Fizi Imports Ltd | Wholesale & retail | 2026 |
| Flagpole Express Limited | Administrative & support | 2006 |
| Flags Express Limited | Extraterritorial | 2010 |
| Flawless Finishes Ltd | Construction | 2010 |
| Fletch Electrical Ltd | Construction | 2014 |
| Flexi Fit UK Ltd | Construction | 2020 |
| Flexy Couriers Ltd | Transport & logistics | 2017 |
| Flexy Solutions Ltd | Wholesale & retail | 2017 |
| Flocking Ltd | Wholesale & retail | 2015 |
| Floe & Harmony Ltd | Professional & scientific | 2017 |
| Flowstate Developments Ltd | Construction | 2026 |