| Reluctant Fitness Ltd | Wholesale & retail | 2025 |
| Rendyr Clothing Ltd | Wholesale & retail | 2025 |
| Renovita Ltd | Real estate | 2023 |
| Renshaw Estates Ltd | Real estate | 2020 |
| Renshaw Wealth Ltd | Extraterritorial | 2025 |
| Renueva Ltd | Professional & scientific | 2022 |
| RES Holdings Limited | Real estate | 2008 |
| Residential Park Homes (Cornwall) Limited | Construction | 2021 |
| Resonant Systems Limited | Manufacturing | 2010 |
| Response Mechanical Services Limited | Energy | 2013 |
| Revvs UP Ltd | Wholesale & retail | 2024 |
| Reynolds Transport Management Services Ltd | Transport & logistics | 2024 |
| RGS Motors Limited | Wholesale & retail | 2007 |
| Rhino Access Solutions Ltd | Construction | 2025 |
| Rhino Civils Limited | Construction | 2021 |
| Rhino UK Group Ltd | Financial services | 2025 |
| Riax Ltd | Transport & logistics | 2016 |
| Richard L Williams Limited | Professional & scientific | 2018 |
| Richardson Brothers Property Limited | Real estate | 2006 |
| Richardson Ceiling Contractors Limited | Construction | 2015 |
| Richardson MOT and Repairs Ltd | Wholesale & retail | 2021 |
| Richdale Sofas Ltd | Manufacturing | 2005 |
| Richmond Air Conditioning Limited | Energy | 2016 |
| Righto Limited | Construction | 2001 |
| Riley Engineering Services(Uk) Ltd | Manufacturing | 2014 |
| Riley Property & Investment Ltd | Financial services | 2025 |
| Riley's & Partners Ltd | Professional & scientific | 2025 |
| Riley's Barbers Limited | Other services | 2025 |
| RJB Electrical Ltd | Construction | 2026 |
| RJS Installations (Midlands) Ltd | Construction | 2016 |
| RJW (Holdings) Limited | Wholesale & retail | 1971 |
| RKD Finance Limited | Financial services | 2016 |
| RL Civils Ltd | Construction | 2022 |
| RL Knighton Ltd | Health & social care | 2016 |
| RLH Properties Ltd | Real estate | 2015 |
| Robbec Limited | Extraterritorial | 2015 |
| Robert Quinn Electrical Services Limited | Construction | 2014 |
| Roberts-Towlson C Limited | Wholesale & retail | 2019 |
| Robin Hood Construction Ltd | Construction | 2019 |
| Robos Plumbing Services Limited | Construction | 2008 |
| Robstock Ltd | Manufacturing | 2016 |
| Rock House Developments (Midlands) Limited | Construction | 2018 |
| Rock House Developments Limited | Construction | 2025 |
| Rockdove Marketing Ltd | Professional & scientific | 2022 |
| Rocky Road Cafe Limited | Hospitality | 2026 |
| Rofoods Limited | Manufacturing | 2025 |
| ROG Braids Limited | Other services | 2026 |
| Rolling Smoke Ilkeston Ltd | Hospitality | 2026 |
| RON Brooks (Holdings) Limited | Wholesale & retail | 1962 |
| RON Brooks Limited | Wholesale & retail | 2002 |
| Ronald Tideswell and Grandson Limited | Real estate | 2015 |
| Roobeedoodle Ltd | Agriculture & fishing | 2021 |
| Roofs ARE US Ltd | Construction | 2024 |
| ROOT2RISE CIC | Education | 2025 |
| Ross Healthcare Limited | Health & social care | 1999 |
| Roxe Enterprises Ltd | Arts & recreation | 2024 |
| Royale Residential Services Ltd | Households | 2012 |
| RP Composite Manufacturing Limited | Manufacturing | 2017 |
| RS Informatics Limited | Information & communication | 2013 |
| RS Ventilation and Electrical Solutions Ltd | Construction | 2025 |
| Rsym Limited | Hospitality | 2021 |
| RT Recycling Limited | Water & waste | 2008 |
| Runnin' Hard Productions Ltd | Information & communication | 2020 |
| Rural Inns Ltd | Hospitality | 2026 |
| Rushcliffe Scaffolding Ltd | Construction | 2022 |
| Rustonix Ltd | Professional & scientific | 2025 |
| Rwfp Services Ltd | Financial services | 2025 |
| Ryans Auto Repairs Ltd | Wholesale & retail | 2017 |
| Ryder's Taverns Ltd | Hospitality | 2013 |
| S & J CAD Services Limited | Professional & scientific | 2013 |
| S & P Financial Group Limited | Financial services | 2025 |
| S and L Brocklehurst Ltd | Wholesale & retail | 2007 |
| S Barlow Electrical Ltd | Construction | 2017 |
| S C Fencing & Building Limited | Construction | 2014 |
| S Morley Holdings Limited | Administrative & support | 2015 |
| S Partridge Consultancy Limited | Professional & scientific | 2025 |
| S Partridge Properties Limited | Real estate | 2024 |
| S&K Flavour House Limited | Hospitality | 2025 |
| S&P Payroll Bureau Ltd | Financial services | 2023 |
| S&R PUB Group Ltd | Hospitality | 2026 |
| S&S Sameday Courier Services Limited | Transport & logistics | 2014 |
| S. a. Parm Limited | Agriculture & fishing | 2013 |
| S.I.M. Fabrications Limited | Manufacturing | 2003 |
| S.P.A. Servicing and Repairs Ltd | Wholesale & retail | 2018 |
| S.T. Trading Limited | Manufacturing | 2007 |
| S.Trueman(Ilkeston,)Limited | Other services | 1958 |
| S5 Safety Solutions Ltd | Public administration | 2022 |
| Sabor Properties Ltd | Real estate | 2023 |
| Sadulski Trans Ltd | Transport & logistics | 2016 |
| Safe 24/7 Security Limited | Construction | 2015 |
| Safe Access Scaffolding (Midlands) Limited | Administrative & support | 2000 |
| Safe Space Cleaners Ltd | Education | 2026 |
| Safe Standard Scaffolding Ltd | Construction | 2025 |
| Safety & Health in Fibre Telecoms | Other services | 2023 |
| Safevision Limited | Manufacturing | 1999 |
| SAL Communications Ltd | Information & communication | 2019 |
| Salba Capital Ltd | Real estate | 2021 |
| Salvage Cars Limited | Wholesale & retail | 2016 |
| Samko and Brother Ltd | Wholesale & retail | 2018 |
| Sanjuzi Ltd | Information & communication | 1998 |