| Event Transport Ltd | Transport & logistics | 2016 |
| Event Trucking Ltd | Transport & logistics | 2015 |
| Evenzy Ltd | Information & communication | 2025 |
| Everlast Jewels Ltd | Manufacturing | 2025 |
| Everstone Landscaping & Build Ltd | Construction | 2026 |
| Everyday Transport Ltd | Transport & logistics | 2024 |
| Evolution Bodyshop Limited | Extraterritorial | 2025 |
| Evolution Smart Limited | Manufacturing | 2016 |
| Exeltel Limited | Information & communication | 2019 |
| Extrahand Care Services Ltd | Health & social care | 2014 |
| Extreme Clean North West Ltd | Administrative & support | 2024 |
| EYE Trace IT Limited | Information & communication | 2014 |
| Eyes First UK Limited | Wholesale & retail | 2019 |
| Eyes Right Opticians 2 Limited | Wholesale & retail | 1997 |
| Eyes Right Opticians Limited | Wholesale & retail | 1993 |
| Ezirtek Ltd | Information & communication | 2023 |
| Ezybike Ltd | Administrative & support | 2018 |
| F. a. Medical Services Ltd | Health & social care | 2021 |
| F.W. Sherratt Limited | Construction | 1948 |
| Faab Properties Limited | Real estate | 2020 |
| FAB Clinic Limited | Other services | 2014 |
| Fabric of Football Limited | Extraterritorial | 2018 |
| Fahdzariyu Limited | Transport & logistics | 2025 |
| Fairway Construction (UK) Limited | Construction | 2015 |
| Faith Pharmacy (Hulme) Limited | Wholesale & retail | 2007 |
| Faith Properties (Hulme) Limited | Real estate | 2026 |
| Families First Ltd | Health & social care | 2024 |
| Family-Help UK Community Interest Company | Professional & scientific | 2026 |
| Fanco Ltd | Health & social care | 2017 |
| Fantom Holdings Limited | Other services | 2016 |
| Farmfix Solution Ltd | Construction | 2025 |
| Fastaction Systems Limited | Health & social care | 2006 |
| FC Autos Ltd | Wholesale & retail | 2023 |
| Feast Avenue Ltd | Hospitality | 2026 |
| Fence IT UK (Inst) Ltd | Construction | 2023 |
| Fern Mill Investments Limited | Administrative & support | 2015 |
| Fern Mill Lettings Limited | Real estate | 2009 |
| Fernwood Construction Limited | Construction | 2025 |
| Fernwood Property Management Limited | Real estate | 2024 |
| Ferryveer Limited | Extraterritorial | 1985 |
| FI Hyde Ltd | Hospitality | 2025 |
| Fieldpark Interiors Limited | Construction | 2000 |
| Filler Pharm Wholesale Ltd | Wholesale & retail | 2025 |
| Final Chapter Tattoo Limited | Other services | 2023 |
| Finance Lead Tech Limited | Information & communication | 2015 |
| Findel Education Limited | Wholesale & retail | 1973 |
| Fine Fibre Fillings (Holdings) Ltd | Financial services | 2022 |
| Fine Fibre Fillings Ltd | Wholesale & retail | 2002 |
| Fire Door Surveys Limited | Construction | 2024 |
| Firefly Barbecue Ltd | Manufacturing | 2013 |
| Firma Studios Ltd | Manufacturing | 2024 |
| First Drop Wholesale Ltd | Wholesale & retail | 2025 |
| First Legal.Ai Ltd | Information & communication | 2026 |
| First Stop Northwest Limited | Administrative & support | 2021 |
| Firstline Property Repairs Ltd | Manufacturing | 2014 |
| Firwood Carpets Denton Ltd | Wholesale & retail | 2023 |
| Fisher Day Limited | Professional & scientific | 2017 |
| Fitlight UK Ltd | Arts & recreation | 2012 |
| Fiva Ltd | Financial services | 2025 |
| Flexon Global Ltd | Wholesale & retail | 2026 |
| FLO Drainage Ltd | Construction | 2025 |
| Floorscape Solutions Group Ltd | Construction | 2025 |
| Flounders Design Ltd | Professional & scientific | 2023 |
| Fluid Rock Ltd | Information & communication | 2025 |
| Flux RIG & Light Limited | Arts & recreation | 2016 |
| Fluxion Labs Ltd | Information & communication | 2026 |
| FMN Group of Anns Ltd Ltd | Wholesale & retail | 2025 |
| Foams 4 Sports Ltd | Manufacturing | 2006 |
| Focused Holdings Limited | Real estate | 2018 |
| Focused Property Consultants Limited | Other services | 2024 |
| Focusflame Limited | Manufacturing | 2009 |
| Foeva Jerk Ltd | Manufacturing | 2026 |
| Food Prep & Go Ltd | Wholesale & retail | 2026 |
| Football FUN Factory (Community 061) Ltd | Arts & recreation | 2022 |
| Football Publishing Limited | Manufacturing | 2013 |
| Fords Property Ltd | Real estate | 2023 |
| Forzadexa Limited | Health & social care | 2026 |
| Foster Pubs Ltd | Hospitality | 2025 |
| Fountain Street Management Company Limited | Households | 2009 |
| Fourtwenty Engineering Ltd | Manufacturing | 2026 |
| Frames & Loaded Ltd | Hospitality | 2026 |
| Frames International Limited | Wholesale & retail | 2026 |
| Frank Massey & SON Limited | Other services | 2002 |
| Fratunes Limited | Administrative & support | 2021 |
| Freddy NW Ltd | Hospitality | 2024 |
| Free Balloon Limited | Information & communication | 2000 |
| Freedom Secure Dog Parks Limited | Other services | 2025 |
| Fresh Auto Care (MCR) Ltd | Wholesale & retail | 2024 |
| Fresh Tropical Ltd | Wholesale & retail | 2024 |
| Freshvue Solutions Limited | Information & communication | 2008 |
| FRS Electrical Ltd | Construction | 2020 |
| Fruity IT Ltd | Information & communication | 2026 |
| Fulcrum Sports Therapy | Education | 2012 |
| Fulford Montessori Nursery Limited | Health & social care | 2014 |
| FUN Chips Ltd | Information & communication | 2011 |
| Futerds Limited | Transport & logistics | 2025 |
| Future Residential (North West) Limited | Other services | 2019 |
| G Bayley Plumbing and Heating Limited | Construction | 2019 |
| G Creative Brand Limited | Arts & recreation | 2023 |
| G.K. Wilson Garden & Landscape Consultancy Limited | Professional & scientific | 2020 |