| Stoic Editing Ltd | Information & communication | 2023 |
| Stone the Crows Landscapes Limited | Construction | 2021 |
| Stop the Clock Design Limited | Other services | 2010 |
| Stove HB Ltd | Hospitality | 2021 |
| Stratlab Limited | Wholesale & retail | 2002 |
| Stratos Chem Limited | Professional & scientific | 2022 |
| Street Ganjees Limited | Hospitality | 2024 |
| Strensall Montessori Nursery Limited | Health & social care | 2023 |
| Strive Accountancy Ltd | Professional & scientific | 2024 |
| Strong House & Victor Motor Ltd | Wholesale & retail | 2015 |
| STS Express Limited | Transport & logistics | 2022 |
| Studio Velvet Ltd | Professional & scientific | 2014 |
| SUE Dawson Financial Services Ltd | Administrative & support | 2013 |
| Sue-Per HR Consultancy Limited | Administrative & support | 2013 |
| Summer Grab Limited | Wholesale & retail | 2026 |
| Summit Close Limited | Administrative & support | 2025 |
| Sunflower CC Property Management Limited | Real estate | 2019 |
| Supreme Upholstery Ltd | Manufacturing | 2016 |
| Sustain Technologies Limited | Construction | 2016 |
| Suwconnectors Ltd | Wholesale & retail | 2026 |
| Svcpboys Limited | Wholesale & retail | 2025 |
| Sveinsson Productions Limited | Information & communication | 2021 |
| SW Management and Events Limited | Public administration | 2021 |
| SWD GEN Limited | Energy | 2023 |
| Sweet FIX (Franchising) Ltd | Hospitality | 2025 |
| Swell UK Limited | Wholesale & retail | 2007 |
| Swifttech IT Solutions Ltd | Information & communication | 2025 |
| SYG Surveying Limited | Professional & scientific | 2025 |
| Syhu Properties Limited | Real estate | 2026 |
| Symposion Entertainment Limited | Information & communication | 2025 |
| Syndicate Original Limited | Wholesale & retail | 2013 |
| Synk Virtual Ltd | Information & communication | 2021 |
| T Property Management Ltd | Hospitality | 2025 |
| T T F Ltd | Wholesale & retail | 1994 |
| T&B Enterprise Ltd | Wholesale & retail | 2020 |
| T&S Mccormick Limited | Hospitality | 2019 |
| T&T Food NW Limited | Wholesale & retail | 2026 |
| T. Renner Ltd | Administrative & support | 2015 |
| T.C. Holdings (Ashton) Limited | Financial services | 2012 |
| T.F.B.S. Limited | Other services | 2002 |
| T.M Prime Distributions Ltd | Wholesale & retail | 2025 |
| T.R. Robinson Holdings Ltd | Financial services | 2023 |
| Tafsi Ltd | Information & communication | 2026 |
| Taitoo Ltd | Water & waste | 2011 |
| TAJ Balti Limited | Hospitality | 2025 |
| Tame Valley Regeneration Consortium Limited | Public administration | 1995 |
| Tameside Computers Limited | Wholesale & retail | 2016 |
| Tameside Health & Wellbeing Ltd | Professional & scientific | 2024 |
| Tameside South and Longdendale Foodbank Limited | Health & social care | 2013 |
| Tameside Sports Trust | Arts & recreation | 1998 |
| Tameside Together CIC | Health & social care | 2026 |
| Tape Range Distributors Limited | Wholesale & retail | 1991 |
| Tarteel Travels Ltd | Administrative & support | 2023 |
| Tate Inns and Entertainment Ltd | Hospitality | 2025 |
| Tate Taverns & Hospitality Ltd | Hospitality | 2025 |
| Tatenda Healthcare Ltd | Health & social care | 2019 |
| Taurus Capital Investments Ltd | Real estate | 2019 |
| Taurus Financial Solutions Ltd | Financial services | 2025 |
| TAX4ALL Claims Limited | Other services | 2017 |
| Taylor & Wood (Tameside) Ltd | Real estate | 2008 |
| Taylor Commissioning Limited | Manufacturing | 2005 |
| Tazify Limited | Professional & scientific | 2025 |
| TBF Trade Limited | Wholesale & retail | 2022 |
| TC4C Properties Limited | Real estate | 2026 |
| TCL (Newco B) Limited | Financial services | 2015 |
| TDM Supplies Limited | Wholesale & retail | 2023 |
| TDT Dynamics Ltd | Wholesale & retail | 2025 |
| Tecbot UK Ltd | Information & communication | 2021 |
| Tech Padeti Limited | Information & communication | 2019 |
| Technos Tech Ltd | Wholesale & retail | 2024 |
| Teho Intelligence Ltd | Information & communication | 2026 |
| Teletek Limited | Information & communication | 2022 |
| Temple Estate Planning Ltd | Professional & scientific | 2024 |
| Tempo Feliz Direct Ltd | Wholesale & retail | 2019 |
| Tessastone Limited | Construction | 1978 |
| Test Air Solutions Limited | Construction | 2005 |
| Textile Technologies Europe Limited | Manufacturing | 1955 |
| Tfbs Group Limited | Other services | 2018 |
| TG Books Ltd | Arts & recreation | 2024 |
| Tgrwdare Limited | Wholesale & retail | 2025 |
| Thai Sabai Massage & Aromatherapy Limited | Health & social care | 2020 |
| Tharmes Building Renovations Limited | Construction | 2021 |
| THE 110 Farm Limited | Agriculture & fishing | 2025 |
| THE Antique Trade LLP | | 2013 |
| THE BE Training Group Ltd | Education | 2024 |
| THE Big Orange Cleaning Company Limited | Administrative & support | 2016 |
| THE Bird Consultancy Limited | Professional & scientific | 1990 |
| THE Boiler Club Online Limited | Construction | 2020 |
| THE Bottle Mill Limited | Hospitality | 2021 |
| THE Brass PIG Company Ltd | Wholesale & retail | 2019 |
| THE Buxton Inn Ltd | Hospitality | 2020 |
| THE Buxton PUB Ltd | Hospitality | 2026 |
| THE Call Centre Careers Company Limited | Other services | 2017 |
| THE Cartography Factory Ltd | Information & communication | 2015 |
| THE Cloud Corner Ltd | Wholesale & retail | 2026 |
| THE Coach Kitchen Limited | Professional & scientific | 2020 |
| THE Cupcake Cabin Limited | Wholesale & retail | 2025 |
| THE Curry Market Limited | Hospitality | 2017 |
| THE DEN Holiday Club Ltd | Health & social care | 2022 |
| THE Dessert Shack MCR Ltd | Hospitality | 2021 |