| ECN Consultants Ltd | Professional & scientific | 2025 |
| Eco Clean East Midlands Limited | Administrative & support | 2014 |
| Eco Technical PH Limited | Construction | 2023 |
| Eco-Composites Ltd | Manufacturing | 2017 |
| Ecobici Investments Ltd | Financial services | 2022 |
| Ecobici Survey Services Limited | Professional & scientific | 2015 |
| Ecogreen Engineering Solutions Limited | Construction | 2020 |
| Ecolife Climate Solutions Limited | Construction | 2026 |
| Econergy Europe Limited | Construction | 2010 |
| Ecotech Projects CIC | Manufacturing | 2022 |
| Ecton Property Company Limited | Real estate | 2026 |
| Ectual Ltd | Professional & scientific | 2024 |
| Eddtoma Holdings Limited | Extraterritorial | 2021 |
| Eden Accounting Limited | Professional & scientific | 2003 |
| Edenverge Limited | Professional & scientific | 2015 |
| Edge Group Consulting Ltd | Information & communication | 2025 |
| Edge Housing Management Ltd | Households | 2026 |
| Edmund Homes Limited | Construction | 2000 |
| Education Personnel Management Limited | Administrative & support | 1992 |
| Edward Farrer Ltd | Construction | 2014 |
| Edward Kingston Developments Limited | Construction | 2018 |
| Edward Kingston Limited | Administrative & support | 1977 |
| Edward Transport Limited | Transport & logistics | 2015 |
| Egates Services Ltd | Professional & scientific | 2025 |
| EGJ Investments Ltd | Real estate | 2020 |
| Eight Asset Management Limited | Extraterritorial | 2024 |
| EJD Brickwork Ltd | Construction | 2025 |
| Ekco Limited | Extraterritorial | 2005 |
| EL Damian ORB Ltd | Wholesale & retail | 2026 |
| EL Gatto Ltd | Wholesale & retail | 2025 |
| Eldrick AI Limited | Information & communication | 2024 |
| Eldrick Holdings Limited | Financial services | 2024 |
| Elec 24/7 (Cambs) Limited | Construction | 2018 |
| Electromedical Products International UK Ltd | Wholesale & retail | 2023 |
| Electronic Control and Measurement Limited | Information & communication | 2018 |
| Elemental Scientific Instruments, Ltd | Professional & scientific | 2014 |
| Elephant Path Wellbeing Ltd | Health & social care | 2025 |
| Elevate to Excelerate Ltd | Wholesale & retail | 2024 |
| Elewellth Ltd | Professional & scientific | 2026 |
| ELG Capital Ltd | Financial services | 2025 |
| Eliseparts.Com Limited | Manufacturing | 2004 |
| Elite 82 Ltd | Arts & recreation | 2022 |
| Elite Driver Development Ltd | Arts & recreation | 2025 |
| Elite Driver Management Ltd | Arts & recreation | 2020 |
| Elite Site Safety Ltd | Construction | 2015 |
| Elitescreens Ltd | Wholesale & retail | 2025 |
| Elkhouly Ltd | Professional & scientific | 2024 |
| Ellaur Limited | Professional & scientific | 1973 |
| Ellegra Creative Limited | Arts & recreation | 2024 |
| Ellington Property Limited | Administrative & support | 2023 |
| Ellis Winters (Fenstanton) Limited | Real estate | 2018 |
| Ellis Winters (Holdings) Limited | Real estate | 2018 |
| Ellis Winters (March) Limited | Real estate | 2015 |
| Ellis Winters (Somersham) Limited | Real estate | 2018 |
| Ellis Winters Limited | Real estate | 2001 |
| ELM PUB Company Limited | Hospitality | 2020 |
| Elmora Ltd | Professional & scientific | 2025 |
| Elsafti Limited | Wholesale & retail | 2025 |
| Eltamimy Homes Ltd | Real estate | 2025 |
| Elysian Business Solutions Limited | Professional & scientific | 2013 |
| Embay Limited | Education | 2025 |
| Embedded Software Solutions Ltd | Information & communication | 2010 |
| EMC Consulting Limited | Professional & scientific | 2022 |
| Emergency Alert Logistics Ltd | Wholesale & retail | 2023 |
| Emeri-Davies Ltd | Health & social care | 2022 |
| EMI J Limited | Transport & logistics | 2023 |
| Emil G Transport Ltd | Transport & logistics | 2019 |
| Emmanuel Business Properties Ltd | Administrative & support | 2015 |
| Emneth Construction and Surfacing Ltd | Construction | 2011 |
| Employment Relations Advice & Solutions Limited | Administrative & support | 2010 |
| Employment Relations Advisory Services Limited | Administrative & support | 2013 |
| Empress Collection Ltd | Real estate | 2026 |
| Enaf Ltd | Professional & scientific | 2026 |
| Encocam Holdings Limited | Financial services | 2021 |
| Encocam Limited | Manufacturing | 1985 |
| Encocam Property Limited | Financial services | 2021 |
| Enercon Services U.K. Limited | Administrative & support | 2005 |
| Enerinvest Advisers Limited | Financial services | 2009 |
| Engagiax Ltd | Information & communication | 2026 |
| Engineering Construction Network Ltd | Professional & scientific | 2020 |
| England Marketing Limited | Administrative & support | 1998 |
| English in Britain Limited | Administrative & support | 1997 |
| Enhance Your Space Landscaping Ltd | Administrative & support | 2025 |
| Enigma Events & Security Limited | Administrative & support | 2011 |
| Enlytic Global Ltd | Information & communication | 2023 |
| ENR Healthcare Services Ltd | Administrative & support | 2019 |
| Enterprise Driveways and Patios Ltd | Construction | 2026 |
| Entrance Investments Ltd | Real estate | 2021 |
| Entrix Holdings Ltd | Financial services | 2026 |
| Epic Mauritius Tours Ltd | Administrative & support | 2025 |
| Epic Parts Limited | Administrative & support | 2018 |
| Epimetheus Investments Ltd | Other services | 2022 |
| Epiphany Communications Ltd | Professional & scientific | 2020 |
| EPM Holdings Limited | Administrative & support | 2023 |
| EQ Recovery Ltd | Transport & logistics | 2025 |
| Equifest Limited | Extraterritorial | 2013 |
| Equiphysio Performance Ltd | Professional & scientific | 2026 |
| Equipment Support Company Limited | Manufacturing | 1991 |
| Equipment Support Group Limited | Financial services | 2021 |
| Eric Pietrac Consulting Ltd | Professional & scientific | 2015 |