| Equilibrium Coaching Ltd | Extraterritorial | 2009 |
| Equinox Capital Holdings Ltd | Financial services | 2025 |
| Equip Sports C.I.C. | Arts & recreation | 2024 |
| ER Musah Limited | Health & social care | 2017 |
| ER Property Group Ltd | Real estate | 2025 |
| ER Therapies Limited | Health & social care | 2025 |
| Eras Event Medical Ltd | Health & social care | 2025 |
| ERC Wind Hull Limited | Professional & scientific | 2025 |
| Eremia Projects Ltd | Real estate | 2023 |
| Ergenix Ltd | Financial services | 2021 |
| Eriac Ltd | Hospitality | 2025 |
| Ermam Holdings Ltd | Financial services | 2026 |
| Ernest & Co Investments Limited | Real estate | 2025 |
| Erox Ltd | Information & communication | 2026 |
| ERP Global Ltd | Information & communication | 2019 |
| ERP Holdco UK Limited | Financial services | 2023 |
| ERP Power Products Limited | Manufacturing | 1999 |
| Errant Apparel Studio Ltd | Manufacturing | 2026 |
| Erreformer Ltd | Arts & recreation | 2020 |
| ERS Removal Services Ltd | Transport & logistics | 2020 |
| Erspinecare Ltd | Arts & recreation | 2020 |
| ERT Realisations Limited | Transport & logistics | 2015 |
| ES Aesthetics Limited | Other services | 2022 |
| Esca Bistro Limited | Hospitality | 2025 |
| Escape Culture Limited | Manufacturing | 2022 |
| Escape Properties Ltd | Real estate | 2022 |
| Escentscia Limited | Manufacturing | 2016 |
| Escobarbers Hull Ltd | Other services | 2026 |
| Escrow-Tech Limited | Information & communication | 2019 |
| Esefibresgrp Ltd | Manufacturing | 2020 |
| ESK (Yorkshire) Limited | Administrative & support | 2024 |
| ESK Commercial Holdings Ltd | Households | 2021 |
| ESL Scaffolding Ltd | Construction | 2020 |
| Eslon Limited | Hospitality | 2026 |
| Espero UK Limited | Professional & scientific | 2000 |
| Esquire (Hull) Limited | Other services | 2006 |
| Essential Pensions Group Limited | Financial services | 2013 |
| Essential Ssas (Trustees) Limited | Professional & scientific | 2014 |
| Essential Ssas Administration Limited | Financial services | 2025 |
| Essential Ssas Limited | Financial services | 2014 |
| Establishing Communities C.I.C. | Health & social care | 2024 |
| Esteem Cleaning Ltd | Other services | 2014 |
| Esteem Facilities Ltd | Other services | 2023 |
| Esteem Laundry Ltd | Other services | 2024 |
| Esteem Stays Ltd | Other services | 2024 |
| Estel Media Holdco Limited | Financial services | 2022 |
| Estelle Beauty Ltd | Wholesale & retail | 2025 |
| Ester Holdings | Financial services | 2022 |
| Esterstyle Fashion Boutique Ltd | Wholesale & retail | 2025 |
| Esther Positioned CIC | Other services | 2021 |
| Esvagt Holdings Limited | Transport & logistics | 2005 |
| Esvagt UK Limited | Transport & logistics | 2005 |
| ETA Corporation Limited | Construction | 2024 |
| Eternal Benefits Ltd | Health & social care | 2000 |
| Eternal Marks Ltd | Manufacturing | 2024 |
| ETH Promotions Ltd | Professional & scientific | 2014 |
| Ethical House Ltd | Manufacturing | 2018 |
| Ethiopian Kitchen Limited | Hospitality | 2025 |
| Ethos Digital Ltd | Professional & scientific | 2026 |
| Etmpro Ltd | Professional & scientific | 2026 |
| ETT Developments Limited | Construction | 2017 |
| Ettridge Architecture Limited | Professional & scientific | 2005 |
| EU International Hull Limited | Wholesale & retail | 2019 |
| EU Takeaway Ltd | Hospitality | 2023 |
| Eurasianhulluk Limited | Hospitality | 2020 |
| Eureka Growing Systems Limited | Construction | 2005 |
| Euro Environmental Ltd | Professional & scientific | 1998 |
| Euro Market 2019 Limited | Wholesale & retail | 2019 |
| Euro Supermarket Hull Limited | Wholesale & retail | 2023 |
| Euro-Ukraine Limited | Administrative & support | 2008 |
| Eurochem (Holdings) Limited | Wholesale & retail | 2005 |
| Eurochem (Northern) Limited | Wholesale & retail | 2001 |
| Eurocycle Adventures Limited | Administrative & support | 2024 |
| Euroka Consulting Limited | Professional & scientific | 2019 |
| Europa Caravans Export Ltd | Manufacturing | 2014 |
| Europa Caravans Ltd | Manufacturing | 2009 |
| Europa GAS Services Limited | Construction | 2016 |
| Europa Maintenance Limited | Construction | 2023 |
| Europa Shipping Services (Newcastle) Limited | Transport & logistics | 1999 |
| Europa Shipping Services Limited | Transport & logistics | 1993 |
| European Mini Market 1 Ltd | Wholesale & retail | 2026 |
| European Mini Market Hull Ltd | Wholesale & retail | 2025 |
| European OFF Licence (Hull) Ltd | Wholesale & retail | 2025 |
| Eurostar Consultants Limited | Professional & scientific | 2002 |
| Eurovision Logistics Ltd | Transport & logistics | 2007 |
| Evaako Ltd | Wholesale & retail | 2024 |
| Evanshallinstallations Ltd | Construction | 2019 |
| Evcloudpay Ltd | Information & communication | 2026 |
| EVE Bird Medical Ltd. | Other services | 2010 |
| Evelyne Ltd | Transport & logistics | 2025 |
| Evenpull Limited | Real estate | 1990 |
| Event Crechers Limited | Health & social care | 2024 |
| Eventus Consulting Ltd | Professional & scientific | 2012 |
| Ever After Holidays Ltd | Administrative & support | 2017 |
| Everco Ltd | Real estate | 2009 |
| Everglow Boilers Ltd | Construction | 2020 |
| Evergreen Funeral Services Ltd | Other services | 2018 |
| Evergreen Simulation and Development Ltd | Real estate | 2010 |
| Everitt Environmental Management Services Limited | Professional & scientific | 2025 |
| Everkinson Services Limited | Other services | 2025 |