| Elysian Wave Rooms Ltd | Other services | 2026 |
| EM and LEW Bargains Ltd | Professional & scientific | 2020 |
| EM and LEW Games Limited | Other services | 2020 |
| EM Personal Training Limited | Arts & recreation | 2024 |
| EMA RO Limited | Manufacturing | 2023 |
| Emad Hull Limited | Hospitality | 2020 |
| Ember Shawarma Ltd | Hospitality | 2026 |
| Emcass Ltd | Other services | 2017 |
| Emerald Care Services (North Lincs) Ltd | Health & social care | 2012 |
| Emerald Holdings Hull Ltd | Financial services | 2026 |
| Emerald North Ltd | Hospitality | 2025 |
| Emerald Securities Ltd | Financial services | 2025 |
| Emily Flooring Limited | Wholesale & retail | 2022 |
| Emitima Limited | Wholesale & retail | 2024 |
| Emmaus Hull & East Riding | Hospitality | 2007 |
| Emmyjay Limited | Transport & logistics | 2025 |
| Empi Energy Services Limited | Construction | 2024 |
| Empire House (Hull) Limited | Hospitality | 2003 |
| Empire Maintenance Ltd. | Construction | 2008 |
| Empire Properties (UK) Limited | Professional & scientific | 2005 |
| Empire Properties (Yorkshire) Limited | Real estate | 2022 |
| Employer Assistant Ltd | Professional & scientific | 2025 |
| Empowerbe Ltd | Administrative & support | 2025 |
| Emso Hull Limited | Real estate | 2025 |
| Emzak Services Limited | Construction | 2012 |
| EN & SN Limited | Professional & scientific | 2024 |
| ENA Care Ltd | Health & social care | 2023 |
| Enable Others Hull Ltd | Education | 2025 |
| Enablement Group (Yorkshire) Ltd | Administrative & support | 2024 |
| Enany Consultant Ltd | Health & social care | 2023 |
| Encasa Limited | Other services | 2012 |
| Enchill Luxe Limited | Other services | 2025 |
| Encore Education Ltd | Education | 2025 |
| Encore Life CIC | Education | 2026 |
| Encore Property Investments Limited | Real estate | 2013 |
| Endike Flooring Limited | Wholesale & retail | 2025 |
| Endike International Store 3 Ltd | Wholesale & retail | 2026 |
| Endike International Store Ltd | Wholesale & retail | 2025 |
| Endike Tandoori Ltd | Hospitality | 2025 |
| Endikebarbers Ltd | Other services | 2025 |
| Endless Consultancy Ltd | Professional & scientific | 2023 |
| Endless Living Ltd | Hospitality | 2022 |
| Endless Shopping Ltd | Wholesale & retail | 2021 |
| Endline Exchange Wholesale Trading Ltd | Wholesale & retail | 2025 |
| Endoscopy (Hull) Limited | Health & social care | 2022 |
| Endrawer Media Ltd | Information & communication | 2010 |
| Enduro Competitions Ltd | Wholesale & retail | 2024 |
| Energix Solar Ltd | Construction | 2025 |
| Energy Building Limited | Professional & scientific | 2004 |
| Energy Demand & Response Limited | Energy | 2016 |
| Energy Options Limited | Manufacturing | 2009 |
| Energy Options Shop Limited | Construction | 2015 |
| Energy Solutions Yorkshire Limited | Administrative & support | 2022 |
| Energy Support Network CIC | Other services | 2025 |
| Enertek Design Limited | Professional & scientific | 2005 |
| Enertek Developments Limited | Professional & scientific | 1997 |
| Enertek R&D Group Limited | Financial services | 2016 |
| Enforcement 24 Limited | Administrative & support | 2016 |
| Engaged Consultancy Ltd | Education | 2020 |
| Engicon Servicers Limited | Construction | 2025 |
| Engine Repair Centre Limited | Wholesale & retail | 2012 |
| Engineering and Design Services Group Ltd | Information & communication | 2012 |
| Engineering QA Ltd | Professional & scientific | 2021 |
| Engio Ltd | Information & communication | 2011 |
| Engwall Ltd | Education | 2025 |
| Enhance Hull Limited | Other services | 2024 |
| Enhance U Ltd | Wholesale & retail | 2021 |
| Eniabire Limited | Wholesale & retail | 2012 |
| Enjoy (UK) Limited | Professional & scientific | 2016 |
| Enjoy the Passion Ltd | Administrative & support | 2021 |
| Ennittproteam Ltd | Arts & recreation | 2025 |
| Enrich Space Ltd | Real estate | 2020 |
| Ensco 1541 Limited | Administrative & support | 2025 |
| Ensoway Limited | Real estate | 2020 |
| Enterprise Joinery & Cabinet Makers Limited | Manufacturing | 2006 |
| Entire Security Solutions Limited | Administrative & support | 2019 |
| Entrepreneur AJ Ltd | Information & communication | 2026 |
| Enviro AC Limited | Administrative & support | 2016 |
| Enviro PV Limited | Administrative & support | 2023 |
| Envirobale Limited | Professional & scientific | 2007 |
| Envirofriendly Recycling (Emea) Limited | Other services | 2020 |
| Envirofriendly Yorkshire Recycling Ltd | Other services | 2019 |
| Envirologistics Consulting & Training Ltd | Professional & scientific | 2020 |
| Enviromail Limited | Manufacturing | 2007 |
| Environmental & Management Solutions Limited | Administrative & support | 2009 |
| Envirowarm Services Limited | Construction | 2013 |
| Enviroworks Limited | Professional & scientific | 2024 |
| Envolve Limited | Professional & scientific | 2015 |
| Eobaesthetics Ltd | Wholesale & retail | 2019 |
| EON Consulting Limited | Professional & scientific | 2004 |
| EON Visual Media Limited | Information & communication | 2003 |
| Epic Barber 1 Ltd | Other services | 2023 |
| Epicompany Limited | Arts & recreation | 2015 |
| Epoch-Uk Ltd | Professional & scientific | 2025 |
| Epoxy Alpha Ltd | Construction | 2020 |
| Epoxy Express Ltd | Wholesale & retail | 2021 |
| Equi Stone Equestrian Ltd | Manufacturing | 2021 |
| Equifab (Northern) Limited | Manufacturing | 2022 |
| Equifab (Pipework) Ltd | Manufacturing | 2025 |
| Equigroup Holdings Ltd | Financial services | 2025 |