| Euro Mini Market (Hudds) Ltd | Wholesale & retail | 2025 |
| Euroconnect Properties Management Limited | Other services | 1997 |
| Eurofast Vintners Limited | Extraterritorial | 1990 |
| Europa Wools Limited | Wholesale & retail | 1988 |
| European Flag Football League (Effl) Ltd | Arts & recreation | 2023 |
| European OGD Limited | Wholesale & retail | 1993 |
| Eurosound Limited | Construction | 2008 |
| Euroway Storage Solutions Ltd | Transport & logistics | 2016 |
| EV Charge and Drive Ltd | Construction | 2022 |
| Evabatcare Solution Limited | Administrative & support | 2024 |
| EVENROUND360 Ltd | Professional & scientific | 2021 |
| Everglow Home Services Ltd | Administrative & support | 2026 |
| Evergreen Manor Care Home Ltd | Health & social care | 2025 |
| Everjoy Limited | Health & social care | 2026 |
| Everleigh Global Ltd | Wholesale & retail | 2025 |
| Everoak Ltd | Construction | 2025 |
| Everpro Ltd | Professional & scientific | 2019 |
| Everscent Ltd | Wholesale & retail | 2025 |
| Evershop PK Limited | Wholesale & retail | 2025 |
| Every Deal Limited | Wholesale & retail | 2025 |
| Everyday Deals Limited | Wholesale & retail | 2025 |
| Everyday Retail Solutions Ltd | Wholesale & retail | 2026 |
| Everytradinggroup Ltd | Real estate | 2026 |
| Eves Eleven Limited | Professional & scientific | 2024 |
| Evil Dave Industries Ltd | Arts & recreation | 2012 |
| Evolution HR Services Limited | Professional & scientific | 2017 |
| Evolution Plasterers Ltd | Construction | 2021 |
| Evolve Electrical Contractors Ltd | Construction | 2019 |
| Evolve Financial Planning Limited | Financial services | 2018 |
| Evolvehq Talent Hub Ltd | Professional & scientific | 2024 |
| Evryroom Ltd | Wholesale & retail | 2022 |
| EWL 95 Ltd | Construction | 2020 |
| EX Service Taxis (HD) Ltd | Transport & logistics | 2024 |
| Exalby Ltd | Information & communication | 2026 |
| Excel Industrial Doors and Shutters (Yorks) Limited | Manufacturing | 2000 |
| Excel Manufacturing Limited | Manufacturing | 2004 |
| Excel Self Storage Ltd | Transport & logistics | 2010 |
| Excel Tyres Huddersfield Ltd | Wholesale & retail | 2024 |
| Excela Group Holdings Limited | Real estate | 2025 |
| Excela Group Limited | Real estate | 2022 |
| Exceljet UK Ltd | Transport & logistics | 2020 |
| Excellence Childcare Holdings Ltd | Education | 2024 |
| Excellence in Coaching Limited | Arts & recreation | 2020 |
| Exclusive Drinks Company Ltd | Hospitality | 2026 |
| Exclusive Finds Ltd | Wholesale & retail | 2024 |
| Exclusive Infusions Limited | Manufacturing | 2025 |
| Exclusive Interiors by Smithson and Littlewood Limited | Construction | 2024 |
| Exen Legal Solutions Limited | Information & communication | 2011 |
| Expansion Plans Limited | Financial services | 2026 |
| Experience Community CIC | Arts & recreation | 2011 |
| Experience Travel (Huddersfield) Limited | Administrative & support | 1985 |
| Experience Vintage Events Limited | Arts & recreation | 2016 |
| Expert Clean Machine Ltd | Administrative & support | 2025 |
| Expert Clean Master Limited | Administrative & support | 2025 |
| Expert Marketing Limited | Administrative & support | 2026 |
| Expert Vehicle Recoveries Ltd | Wholesale & retail | 2025 |
| Explore Arabic Limited | Education | 2023 |
| Explorecrafts Ltd | Wholesale & retail | 2018 |
| Export House Management Company Limited | Real estate | 2005 |
| Exportwins Limited | Other services | 2016 |
| Express Car Hire Services Limited | Wholesale & retail | 2008 |
| Express Car Wash Ltd | Professional & scientific | 2016 |
| Express Estates & Lettings Ltd | Real estate | 2017 |
| Express Hair System Ltd | Other services | 2024 |
| Express Laundry (Yorkshire) Limited | Other services | 2015 |
| Express Local Ltd | Wholesale & retail | 2017 |
| Express Office Solutions Limited | Administrative & support | 2012 |
| Express Services(Gb) Ltd | Wholesale & retail | 2010 |
| Express Shop Online Ltd | Wholesale & retail | 2025 |
| Expressions Kitchens & Bedrooms Limited | Construction | 2001 |
| EXS Commerce and Trade Ltd | Wholesale & retail | 2022 |
| External Coatings Limited | Construction | 2018 |
| Extract Technology Limited | Manufacturing | 2025 |
| Extreme Conditioning Ltd | Arts & recreation | 2013 |
| Extreme Fitness Ltd | Wholesale & retail | 2020 |
| Eyakkam Dance Theatre Ltd. | Arts & recreation | 2025 |
| EYE Care Optics Ltd | Health & social care | 2023 |
| EYE Clinic at Home Limited | Health & social care | 2007 |
| EYE Health Ltd | Health & social care | 2014 |
| EYE Optics Plus Limited | Professional & scientific | 2010 |
| Eyegames Holdings Limited | Financial services | 2021 |
| Eyegames Limited | Information & communication | 2012 |
| Eyel Ltd | Education | 1994 |
| Eyesky Limited | Administrative & support | 2020 |
| EYM RES Ltd | Real estate | 2026 |
| Ezi-Tech Ltd | Information & communication | 2023 |
| Ezzequestto Accounting Ltd | Professional & scientific | 2026 |
| F & R Engineering Ltd | Professional & scientific | 2025 |
| F and M Investments Ltd | Real estate | 2025 |
| F and O Clothing Ltd | Wholesale & retail | 2026 |
| F Auto Repairs Ltd | Wholesale & retail | 2025 |
| F Autos Huddersfield Ltd | Wholesale & retail | 2020 |
| F Hameed Medical Services Ltd | Health & social care | 2016 |
| F M G Support (HO) Limited | Administrative & support | 1998 |
| F Mirza Ltd | Professional & scientific | 2019 |
| F MON Limited | Hospitality | 2025 |
| F N P Power Services Ltd | Administrative & support | 2024 |
| F&A Asset Management Ltd | Real estate | 2025 |
| F&A Surgical Limited | Health & social care | 2009 |
| F.A.J. Investments Limited | Construction | 1997 |