| DOE LEA Properties Ltd | Real estate | 2010 |
| Dofii Inspirational Software Ltd | Information & communication | 2025 |
| Dogley Apartments Management Company Limited | Real estate | 2007 |
| Doha Dreams Inc Ltd | Education | 2018 |
| Doit Contracting Ltd | Information & communication | 2016 |
| Doitnow Solutions Ltd | Professional & scientific | 2025 |
| Dolce Vita Private Ltd | Hospitality | 2021 |
| Dolce-Vita Care Ltd | Administrative & support | 2023 |
| Dollar East Huddersfield Limited | Other services | 2007 |
| Dolly Lane Car Park Ltd | Real estate | 2014 |
| Dolphin Security Service PVT Ltd | Administrative & support | 2023 |
| DOM & SAM Property Investments Limited | Real estate | 2025 |
| Domenico (UK) Ltd | Hospitality | 2011 |
| Domestic Angel Ltd | Administrative & support | 2010 |
| Domestic Cleaner & Social Media Business Ltd | Administrative & support | 2023 |
| Dominion Domaines Ltd | Administrative & support | 2024 |
| Domker Limited | Construction | 2024 |
| DON Pepes Food Limited | Hospitality | 2025 |
| Donald Heath Cartons Limited | Other services | 2003 |
| Donald Heath Waste Paper Limited | Administrative & support | 2003 |
| Donaldson's Development Ltd | Real estate | 2021 |
| Donaldson's Holdings Ltd | Real estate | 2018 |
| Donaldson's Topco Ltd | Real estate | 2021 |
| Donaldson's Vets Limited | Professional & scientific | 2011 |
| Donaldsons Decorating Services Limited | Construction | 2003 |
| Donaldson’S Properties Holdings Ltd | Financial services | 2022 |
| Donaldson’S Properties Ltd | Real estate | 2022 |
| Done Courier Ltd | Transport & logistics | 2026 |
| Dong Dong Ltd | Wholesale & retail | 2016 |
| Doodes Limited | Administrative & support | 2013 |
| Doodles OUT of School Club Limited | Education | 2007 |
| Doorphoria Ltd | Wholesale & retail | 2022 |
| Dora the Label Ltd | Wholesale & retail | 2019 |
| Doratech Ltd | Information & communication | 2011 |
| Dorcas Inclusive Education Consultancy Ltd | Education | 2019 |
| Dorchester Accommodations Ltd | Hospitality | 2024 |
| Dorm Supermarket Ltd | Wholesale & retail | 2018 |
| Dosa Tales Ltd | Hospitality | 2025 |
| DOT Communications Ltd | Other services | 2022 |
| DOT to DOT Finance Ltd | Professional & scientific | 2024 |
| Dotwave Commerce Ltd | Wholesale & retail | 2025 |
| Double J. Cash & Carry & Wholesalers Limited | Real estate | 1976 |
| Double Stones Shoot Limited | Administrative & support | 2017 |
| Dough in the Dales Ltd | Real estate | 2022 |
| Douglas J Engineering Limited | Professional & scientific | 2008 |
| Doup Ltd | Wholesale & retail | 2025 |
| Dovenor Services Limited | Water & waste | 1992 |
| Dovetop Limited | Real estate | 1990 |
| Downey Properties Limited | Wholesale & retail | 2017 |
| Downey Textile Installations Limited | Manufacturing | 2024 |
| Downtown Fast Foods Ltd | Other services | 2022 |
| Dowse Services Ltd | Administrative & support | 2021 |
| Doyle Properties Limited | Real estate | 2019 |
| Doyne Mechanical Services Limited | Construction | 2012 |
| DP Fibre Ltd | Professional & scientific | 2021 |
| DPH Holdings Limited | Administrative & support | 2020 |
| DPM Enforcement Ltd | Administrative & support | 2020 |
| DPR Limited | Construction | 2005 |
| DPT Solutions Limited | Real estate | 1981 |
| Dptaverns Limited | Hospitality | 2025 |
| DR CJ Lifestyle Ltd | Information & communication | 2025 |
| DR Franks Yorkshire Oncology Limited | Health & social care | 2019 |
| DR Herb Limited | Wholesale & retail | 2026 |
| DR HIU Servicing Ltd | Construction | 2022 |
| DR I HUS Ltd | Health & social care | 2024 |
| DR JET Detailing Clinic Ltd | Administrative & support | 2024 |
| DR LIZ Mear, Consultant, Chair and Coach Limited | Professional & scientific | 2022 |
| DR Neuro Ltd | Information & communication | 2022 |
| DR PD Dickinson Oncology Limited | Health & social care | 2025 |
| DR PKR Ltd | Professional & scientific | 2022 |
| DR Sonya Limited | Health & social care | 2019 |
| DR T Consultancy Ltd | Health & social care | 2022 |
| DR Vicki Shaw & Associates Limited | Professional & scientific | 2014 |
| DR Z Ltd | Health & social care | 2019 |
| DR. Richard Aubrey Ltd | Health & social care | 2014 |
| DRA Enterprises Ltd | Real estate | 2018 |
| DRA Tower Crane Services & Hire Ltd | Administrative & support | 2007 |
| Dragon Design & Development Ltd | Real estate | 2024 |
| Dragonfly Case Management Services Ltd | Health & social care | 2023 |
| Dragonfly Products Limited | Wholesale & retail | 2019 |
| Drain Trace Limited | Water & waste | 2004 |
| Dramatic Cleans Ltd | Administrative & support | 2021 |
| Draw Time Competitions Ltd | Wholesale & retail | 2025 |
| DRD Partners Ltd | Health & social care | 2022 |
| Drealz Global Ltd | Wholesale & retail | 2025 |
| Dream Comfort Ltd | Wholesale & retail | 2025 |
| Dream Galleries Ltd | Wholesale & retail | 2018 |
| Dream Gallery Ltd | Wholesale & retail | 2017 |
| Dream Nest Beds Ltd | Manufacturing | 2026 |
| Dream Property Holdco Limited | Financial services | 2017 |
| Dreamz Enterprise Limited | Extraterritorial | 2024 |
| Dressflix Ltd | Wholesale & retail | 2025 |
| DRH Cycle Technology Limited | Wholesale & retail | 2021 |
| DRH Pharma Ltd | Health & social care | 2017 |
| Driftfy Travel Ltd | Wholesale & retail | 2023 |
| Driftwood Timber Merchants Ltd | Wholesale & retail | 2023 |
| Drighlington Fibres Limited | Professional & scientific | 2001 |
| Drink CBD UK Ltd | Wholesale & retail | 2024 |
| Drive 2 Pass Ltd | Education | 2025 |
| Drive by Media Limited | Professional & scientific | 2016 |