| Roundstone Caravan Depot LLP | | 2015 |
| Rowan Removals Ltd | Wholesale & retail | 2021 |
| Rpardon Limited | Information & communication | 2005 |
| RPC Sussex Ltd | Manufacturing | 2024 |
| RPS Consulting (London) Ltd | Other services | 2018 |
| RPS Contractors Limited | Construction | 2008 |
| Rrmkr Ltd | Other services | 2017 |
| RRP Electrical Contractors Limited | Construction | 2001 |
| RS Gutter Plus Ltd | Construction | 2023 |
| RSI (UK) and Company Limited | Construction | 2000 |
| Rspca Assured Limited | Other services | 1992 |
| RST Design Consultants Ltd | Professional & scientific | 2025 |
| RTL Site Services Ltd | Construction | 2023 |
| Rtvss Ltd | Administrative & support | 2025 |
| Rubi Cars Limited | Transport & logistics | 2018 |
| Rudgwick Gardens Limited | Administrative & support | 2021 |
| Rudgwick Healthcare Limited | Wholesale & retail | 2008 |
| Rudgwick Management Company Limited | Households | 2022 |
| Rufus Street Consulting Limited | Professional & scientific | 2024 |
| Ruiz Healthcare Services Limited | Health & social care | 2013 |
| Rukn Thabit Ltd | Wholesale & retail | 2026 |
| Ruminant Health Solutions Limited | Professional & scientific | 2023 |
| Runpath Employee Trustee Limited | Professional & scientific | 2009 |
| Rush Management Limited | Transport & logistics | 1997 |
| Rushleigh Consulting Ltd | Professional & scientific | 2013 |
| Rusper Road Property Management Company Limited | Households | 1998 |
| Rusper Technical Services Limited | Administrative & support | 2015 |
| Rusper Village Stores Limited | Wholesale & retail | 1991 |
| Russ Aviation Ltd | Professional & scientific | 2016 |
| Ruth Singleton Limited | Administrative & support | 2019 |
| RV Healthcare Services Ltd | Health & social care | 2017 |
| RVG Investments Ltd | Other services | 2010 |
| Rwfm Group Ltd | Information & communication | 2019 |
| RWH Consultants Limited | Information & communication | 2014 |
| Ryan James Benson Commercials Ltd | Wholesale & retail | 2019 |
| Ryan's Holdings Limited | Manufacturing | 1990 |
| Ryanco Ltd | Real estate | 2026 |
| RYF Limited | Professional & scientific | 2021 |
| Ryman Control Systems Limited | Manufacturing | 1995 |
| S & B Property Investments Ltd | Real estate | 2022 |
| S & M Special Gases Limited | Professional & scientific | 1997 |
| S and M Tyres Holdings Limited | Professional & scientific | 2009 |
| S and M Tyres Limited | Agriculture & fishing | 1975 |
| S Beasley Ltd | Construction | 2002 |
| S C Contractors Limited | Construction | 2010 |
| S D Plastics Ltd | Extraterritorial | 2026 |
| S G North Field Limited | Administrative & support | 2025 |
| S G Plastering (Surrey) Ltd | Construction | 2018 |
| S J M Landscape Services Limited | Professional & scientific | 2001 |
| S J M Landscapes Limited | Administrative & support | 2001 |
| S Mccreadie Ltd | Construction | 2015 |
| S T Logic Limited | Education | 2005 |
| S&D Buildx Ltd | Construction | 2025 |
| S. a. Technical Services Ltd | Energy | 2017 |
| S. E. Contractors Limited | Manufacturing | 2014 |
| S. Sloan & Company Ltd | Professional & scientific | 2025 |
| S.A.S Pools Ltd | Construction | 2024 |
| S.R.Services (South East) Limited | Wholesale & retail | 2003 |
| S.U.V.Me Ltd | Wholesale & retail | 2019 |
| SA ACQ Limited | Other services | 2023 |
| SA Jackson Haulage Limited | Transport & logistics | 2018 |
| SA LA VIE UK Ltd | Wholesale & retail | 2023 |
| Saber Training Ltd | Administrative & support | 2015 |
| Sabi Consulting Ltd | Professional & scientific | 2026 |
| Sabien Ltd | Health & social care | 2014 |
| SAC 2015 Limited | Extraterritorial | 2015 |
| Sacrosync Limited | Arts & recreation | 2015 |
| Sadvastu Consultancy Ltd | Professional & scientific | 2016 |
| Safe-Pcb UK Ltd | Professional & scientific | 2017 |
| Safechoice Media Technologies Limited | Information & communication | 2025 |
| Safeguard Chemicals Limited | Professional & scientific | 1992 |
| Safeguard Europe Limited | Manufacturing | 1983 |
| Safeguard Holdings Limited | Manufacturing | 2021 |
| Safeguard Wills Ltd | Professional & scientific | 2019 |
| Safety, Environmental, Advisors & Suppliers Ltd | Professional & scientific | 2017 |
| Saham Park Estates Limited | Real estate | 2015 |
| Saham Park Investments Limited | Real estate | 2015 |
| Sahota Ventures Limited | Real estate | 2025 |
| Saim Cars Ltd | Wholesale & retail | 2024 |
| Saint James Homes Ltd | Construction | 2026 |
| Saivim Ltd | Health & social care | 2023 |
| Saje Consulting Ltd | Professional & scientific | 2019 |
| Salcombe G Limited | Households | 2023 |
| Salespro Technology Ltd | Information & communication | 2023 |
| Salfo Properties Ltd | Real estate | 2023 |
| Sally Bateson Consulting Limited | Professional & scientific | 2017 |
| Sally Sanderson Ltd | Professional & scientific | 2003 |
| Saloncide Solutions Ltd | Wholesale & retail | 2011 |
| Saltdean Close Management Company Limited | Hospitality | 1990 |
| Saltpost Limited | Education | 2014 |
| Saltydog Properties Ltd | Real estate | 2020 |
| Salubrious Living Limited | Information & communication | 2015 |
| Salutem Omnium Ltd. | Professional & scientific | 2012 |
| SAM Paul Heating Limited | Construction | 2015 |
| SAM Smith Ltd | Information & communication | 2021 |
| SAM Winser Limited | Information & communication | 2019 |
| SAM&SIM1 Ltd | Wholesale & retail | 2026 |
| Sameday Logistic Solutions Limited | Transport & logistics | 2010 |
| Samphire Design Limited | Professional & scientific | 2014 |
| Samphire Photography Limited | Professional & scientific | 2015 |