| Shaw Inns Limited | Hospitality | 2026 |
| Shaz Properties London Ltd | Real estate | 2024 |
| Shazhome Limited | Wholesale & retail | 2018 |
| Shea Schvantz Limited | Real estate | 2026 |
| Shehram Limited | Wholesale & retail | 2026 |
| Shergill Brothers Property Developments Ltd | Construction | 2019 |
| Shergill Build & Maintain Ltd | Construction | 2026 |
| Shergill Construction Ltd | Construction | 2002 |
| Shergill Property Co. Limited | Real estate | 2003 |
| Shergill Property Investments Ltd | Real estate | 2013 |
| Shimmer Estates Ltd | Real estate | 2023 |
| Shin Trading Ltd | Other services | 2025 |
| Shiptivity Limited | Transport & logistics | 2019 |
| Shiron Estates Ltd | Real estate | 2020 |
| Shiron Property Services Limited | Real estate | 2017 |
| Shish Exppress Ltd | Hospitality | 2023 |
| SHN Properties Limited | Real estate | 2005 |
| Shollymor Consulting Ltd | Health & social care | 2022 |
| Shoorah Ltd | Information & communication | 2022 |
| Shop-Ellara Ltd | Wholesale & retail | 2025 |
| Shor Commodities Ltd | Wholesale & retail | 2024 |
| Shreeji Sada Ltd | Wholesale & retail | 2024 |
| Shreeya Ltd | Information & communication | 2011 |
| Shri Hari Technologies Limited | Information & communication | 2024 |
| Shrink Ltd | Health & social care | 2016 |
| Shrink Property Ltd | Financial services | 2025 |
| Shrublands Properties Limited | Real estate | 2017 |
| Shrz Ltd | Transport & logistics | 2023 |
| Shure Secure Limited | Administrative & support | 2017 |
| SI Contracting Ltd | Professional & scientific | 2025 |
| Siam Financials Limited | Professional & scientific | 2026 |
| SIB UK PVT Ltd | Professional & scientific | 2017 |
| Sibana Limited | Hospitality | 2024 |
| Sickle Cell Outreach Limited | Health & social care | 2024 |
| Sidhhanth Limited | Information & communication | 2025 |
| Signature Furniture Limited | Manufacturing | 2013 |
| Sigo Consultancy Ltd | Wholesale & retail | 2025 |
| Silver Key Solutions Limited | Information & communication | 2010 |
| Silver Skills Ltd | Education | 2015 |
| Silver Sky Crystals Limited | Wholesale & retail | 2024 |
| Silver-Canopy UK Ltd | Construction | 2022 |
| Sima & D Limited | Health & social care | 2021 |
| Simon Alexander Limited | Administrative & support | 2006 |
| Simon Booth Construction Limited | Construction | 2001 |
| Simple Leisure Solutions Limited | Professional & scientific | 2008 |
| Simple Lifestyle Services Limited | Professional & scientific | 2014 |
| Simple Logistics Limited | Administrative & support | 2022 |
| Simple Solution (UK) Ltd | Professional & scientific | 2011 |
| Simply Facades Ltd | Construction | 2021 |
| Simply Finest Ltd | Wholesale & retail | 2020 |
| Simply Flooring Contracts Ltd | Construction | 2023 |
| Simply Glass Limited | Manufacturing | 2001 |
| Simply Meds Pro Ltd | Wholesale & retail | 2018 |
| Simply Plumbing Ltd | Other services | 2014 |
| Simply Scaffolding (Services) Limited | Construction | 2012 |
| Simply Shawwarma Ltd | Hospitality | 2025 |
| Simplyteeth Brentwood Ltd | Health & social care | 2025 |
| Simplyteeth Hornchurch Ltd | Health & social care | 2024 |
| Simplyteeth Ilford Ltd | Health & social care | 2015 |
| Simplyteeth Ltd | Administrative & support | 2010 |
| Simplyteeth Stanford LE Hope Ltd | Professional & scientific | 2015 |
| Simplyteeth Stansted Ltd | Professional & scientific | 2015 |
| Simsar Ltd | Information & communication | 2024 |
| Sina Mechanical Limited | Construction | 2018 |
| Sincerely Thai Ltd | Other services | 2021 |
| Singh and Deliver Ltd | Other services | 2011 |
| Singh and Shout Ltd | Information & communication | 2011 |
| SIP Shops Ltd | Information & communication | 2025 |
| SIP! Bubble Tea Ltd | Wholesale & retail | 2024 |
| Sirghi Quality Services Ltd | Transport & logistics | 2013 |
| Sirius Service Group Ltd | Administrative & support | 1993 |
| Sita Podcasting Ltd | Information & communication | 2022 |
| Sitech Solutions Limited | Information & communication | 2018 |
| Sixty 3 Ltd | Health & social care | 2005 |
| SJ Bourdon Properties Ltd | Real estate | 2024 |
| SJ Travel & Dine Ltd | Hospitality | 2023 |
| SJ Vision Limited | Health & social care | 2025 |
| SJJ Properties LLP | | 2016 |
| SJK Interiors Ltd | Construction | 2024 |
| SJM Global Services Ltd | Professional & scientific | 2020 |
| Sjtcare Limited | Health & social care | 2024 |
| SK Architecture Studios Ltd | Professional & scientific | 2025 |
| SK Electrical Installations Ltd | Construction | 2026 |
| SK Holding London Ltd | Financial services | 2024 |
| SK Investments Essex Ltd | Real estate | 2025 |
| SK Salam Ltd | Transport & logistics | 2025 |
| SK Sales & Construction Ltd | Construction | 2020 |
| SK Support Services Ltd | Health & social care | 2026 |
| SK Uraswamys Ltd | Hospitality | 2024 |
| Skcg BTL Limited | Real estate | 2017 |
| Skcg Leisure Ltd | Other services | 2014 |
| Skcg Properties Limited | Construction | 2015 |
| Skcg Services Limited | Administrative & support | 2021 |
| SKH Management Ltd | Other services | 2016 |
| SKI Automoto Limited | Manufacturing | 2008 |
| Skin LAB Beauty Clinic Ltd | Other services | 2023 |
| Skin LAB Medical Academy Ltd | Education | 2023 |
| Skin LAB Medical Surgery Ltd | Health & social care | 2023 |
| Skin Society Clinic and Academy Limited | Other services | 2026 |
| Skip Hire Team Limited | Water & waste | 2023 |