| THE ST James the Less Preservation Trust | Arts & recreation | 2004 |
| THE Tent People Limited | Arts & recreation | 2020 |
| THE Torr Vale TAP Ltd | Hospitality | 2023 |
| THE Torrs (New Mills) Ltd | Hospitality | 2013 |
| THE Tourist Group Limited | Administrative & support | 2023 |
| THE Whaley Bridge Community Trust | Education | 2002 |
| THE Wildboarclough Water Company Limited | Water & waste | 2016 |
| Theretocare Ltd | Health & social care | 2023 |
| Thinkvoyd Ltd | Information & communication | 2025 |
| Third Place Events Ltd | Arts & recreation | 2023 |
| Thogan Ltd | Real estate | 2026 |
| Thornsett Tailor Made Furniture Ltd | Manufacturing | 2024 |
| Thornton Engineering Design & Consulting Ltd | Administrative & support | 2016 |
| Thoughtwave Technologies Ltd | Information & communication | 2000 |
| Three Tulips Homes Ltd | Real estate | 2025 |
| Throoput Ltd | Information & communication | 2023 |
| Tigerbird Limited | Information & communication | 2013 |
| Till Data and BI Solutions Ltd | Information & communication | 2018 |
| TJ Accounting Solutions Limited | Professional & scientific | 2004 |
| TJ Taxation Solutions Limited | Professional & scientific | 2005 |
| TJS Living Ltd | Hospitality | 2026 |
| TM Private Hire Limited | Transport & logistics | 2011 |
| Tmco. Translation & Interpreting Ltd | Professional & scientific | 2020 |
| Tooks Catering Supplies Ltd | Administrative & support | 2012 |
| Tooks CHS Ltd | Administrative & support | 2026 |
| Tordoff Rail and Accessibility Consulting Limited | Transport & logistics | 2018 |
| Torq Design Ltd | Professional & scientific | 2025 |
| Torr Top Holdings Limited | Hospitality | 2018 |
| Torr Vale Mills Limited | Arts & recreation | 1976 |
| Torrside Brewing Ltd | Manufacturing | 2014 |
| Totus Group Limited | Water & waste | 2023 |
| Townsend Board Limited | Wholesale & retail | 2019 |
| Townsend Mortgage Solutions Ltd | Financial services | 2021 |
| Tracks and Trails Ltd | Arts & recreation | 2011 |
| Trademaster (2006) Limited | Construction | 2006 |
| Trademaster Paints Limited | Extraterritorial | 2006 |
| Traditional Engineering Company Limited | Manufacturing | 2006 |
| Tramar Services Limited | Construction | 1998 |
| Transport Brokerage Ltd | Transport & logistics | 2011 |
| TRANSPORT8 Ltd | Other services | 2024 |
| Trenchard Projects Limited | Construction | 2008 |
| TRI Crest Construction Ltd | Construction | 2026 |
| Trinity Mews Maintenance Company Ltd | Extraterritorial | 2016 |
| TRU TAN High Peak Limited | Other services | 2025 |
| Truemass Ltd | Professional & scientific | 2018 |
| Trusted IT Ltd | Wholesale & retail | 2003 |
| TSJ Clinical Pharm Limited | Health & social care | 2025 |
| TSS Locks Ltd | Administrative & support | 2012 |
| Tunstead Mill Limited | Financial services | 2020 |
| Twenty Trees Catering Ltd | Hospitality | 2025 |
| TWIST2SOLVE Ltd | Arts & recreation | 2026 |
| Two for Joy Photography Limited | Professional & scientific | 2015 |
| Tylo Ltd | Construction | 2016 |
| Typhoon Anchor Products Ltd | Manufacturing | 2020 |
| U3 Partners Limited | Information & communication | 2026 |
| Udaya Holdings Ltd | Financial services | 2026 |
| UK Breaks Flats Ltd | Real estate | 2022 |
| UK Breaks Ltd | Hospitality | 2021 |
| UK Helicopters Ltd | Transport & logistics | 2023 |
| Ukiyo Consulting Limited | Professional & scientific | 2016 |
| Unbranded Consulting LLP | | 2016 |
| Unique Systems 2020 Ltd | Professional & scientific | 2020 |
| Upper Park Capital Management Limited | Professional & scientific | 2016 |
| Urban Photography Ltd | Professional & scientific | 2021 |
| Urban Roots Gardens Ltd | Other services | 2020 |
| Ursa-Etc Limited | Education | 2025 |
| Ustun Catering Ltd | Hospitality | 2022 |
| Utility & Infrastructure Solutions Ltd | Construction | 2025 |
| Utility Audit North West Ltd | Professional & scientific | 2016 |
| Utility Infrastructure Solutions Limited | Construction | 2018 |
| V&P Property Holdings Ltd | Real estate | 2026 |
| V.A.K Conveying Systems Limited | Manufacturing | 1994 |
| VA Angels Academy Ltd | Education | 2022 |
| Vanist Supply Co. Ltd | Manufacturing | 2019 |
| Venus Accounting Services Limited | Professional & scientific | 2007 |
| Veridical Communications Ltd | Professional & scientific | 2025 |
| Versible Ltd | Information & communication | 2023 |
| Vialet Consultants Limited | Professional & scientific | 2020 |
| Vicen Property Limited | Real estate | 2024 |
| Victoria Whittle Ltd | Professional & scientific | 2016 |
| Vigo Projects Limited | Information & communication | 2021 |
| Viking Independent Funeral Services Ltd | Administrative & support | 2016 |
| Village Saver New Mills Ltd | Wholesale & retail | 2021 |
| Vinyl Partners LLP | | 2015 |
| Violets and Daisies Ltd | Wholesale & retail | 2018 |
| Virtus Law Limited | Professional & scientific | 2015 |
| Visit Whaley Bridge CIC | Arts & recreation | 2026 |
| Vista Engineering Limited | Manufacturing | 1979 |
| Vista Plastics Limited | Administrative & support | 1989 |
| Vivien Cross Accountancy Services Limited | Professional & scientific | 2020 |
| Vixco Ltd | Real estate | 2021 |
| W B Cycles Ltd | Wholesale & retail | 2023 |
| W. a. Howden & Sons Limited | Transport & logistics | 2011 |
| W. Rigby & SON Property Limited | Real estate | 2009 |
| W. Rigby and SON Limited | Wholesale & retail | 1997 |
| W. Rigby Power Limited | Wholesale & retail | 2013 |
| W.B.Fields Limited | Households | 2016 |
| W.Brindley's Funeral Service Limited | Other services | 2006 |
| W.C.H. Properties Limited | Real estate | 2003 |
| Wakefield Fabrications NW Limited | Manufacturing | 2015 |