| PEP Ground Rents Limited | Real estate | 2016 |
| Petals (Hexham) Limited | Wholesale & retail | 2001 |
| Petheram Medical Ltd | Professional & scientific | 2016 |
| Peyton MAE Home Decor Ltd | Wholesale & retail | 2018 |
| PGT Labs Limited | Information & communication | 2024 |
| PGW Consultancy Services Ltd | Professional & scientific | 2024 |
| Pharma Site Services Limited | Manufacturing | 2017 |
| Phoenix Energy Partners Limited | Financial services | 2021 |
| Phoenix House (Newcastle) Limited | Households | 2016 |
| Phone Tech Repair Hexham Ltd | Wholesale & retail | 2024 |
| Phonebox (Hexham) Limited | Wholesale & retail | 2003 |
| Phonebox Telecom Limited | Information & communication | 2011 |
| Pinpoint Adventure Ltd | Education | 2026 |
| Pioneering Opportunities Limited | Professional & scientific | 2022 |
| Pique Gosforth Limited | Hospitality | 2024 |
| Pleccy Ltd | Professional & scientific | 2022 |
| Potts Broadcast Rigging Limited | Professional & scientific | 2023 |
| Poultry Heaters Ltd | Wholesale & retail | 2023 |
| Precision Fitness Limited | Health & social care | 2013 |
| Premier Bookkeeping & Accountancy Ltd | Professional & scientific | 2010 |
| Premier Evenings Limited | Other services | 2002 |
| Premier Football Development Ltd | Education | 2023 |
| Premier Truck Hire Limited | Administrative & support | 2004 |
| Preneur Network Ltd | Professional & scientific | 2022 |
| Prestige Automotive Hire Limited | Administrative & support | 2025 |
| Prestige Performance Collection Limited | Other services | 2025 |
| Preystone Property Investments Limited | Hospitality | 1987 |
| Prime Management (N.E.) Limited | Professional & scientific | 2017 |
| Prime Racing Limited | Extraterritorial | 2013 |
| PRIME1 Services Limited | Health & social care | 2024 |
| Prism Logistical Services Group Limited | Financial services | 2016 |
| Prism Logistical Services Limited | Professional & scientific | 2005 |
| Pro Performance Sports Coaching Ltd | Education | 2024 |
| Proactive Wealth Management Limited | Financial services | 2026 |
| Property, Gardens and Flowers Limited | Administrative & support | 2015 |
| PROPERTY2.0 Ltd | Real estate | 2025 |
| Protection Regulation Outsourcing Limited | Public administration | 2019 |
| PST Shunting Ltd | Transport & logistics | 2010 |
| Psych Medicolegal Reporting Limited | Administrative & support | 2022 |
| Pubs Matter Limited | Hospitality | 2009 |
| Pulmonary Homeostasis Ltd | Professional & scientific | 2022 |
| Purple Stripe Ltd | Households | 2019 |
| Puzhou International Limited | Water & waste | 2009 |
| Pwjb Consultancy Limited | Professional & scientific | 2019 |
| Pyramid Football Development Ltd | Arts & recreation | 2025 |
| Quad Crop Energy Limited | Extraterritorial | 2015 |
| Qualis Holdings Limited | Real estate | 2022 |
| Qualis Renewables Limited | Construction | 2020 |
| Quantum European Ltd | Transport & logistics | 2015 |
| Quantumcomps Ltd | Arts & recreation | 2026 |
| Queen's Hall Arts | Arts & recreation | 2000 |
| Quirky Wellbeing CIC | Administrative & support | 2026 |
| Qvec UK Ltd | Wholesale & retail | 2026 |
| R & C Timber Logging Limited | Agriculture & fishing | 2014 |
| R & H Scott Limited | Transport & logistics | 2003 |
| R a Charlton Ltd | Agriculture & fishing | 2012 |
| R Clark Developments Ltd | Construction | 2019 |
| R H L Davies LLP | | 2024 |
| R P Mayland Ltd | Agriculture & fishing | 2024 |
| R. Arnott & Sons Limited | Construction | 1962 |
| R380 Automotive Limited | Wholesale & retail | 2025 |
| RA & BA Ridley & SON Limited | Agriculture & fishing | 2017 |
| Radcliffe Park Management Company Limited | Households | 2003 |
| Radiology Chambers Limited | Health & social care | 2020 |
| Raine Medical Limited | Health & social care | 2010 |
| Randlap Consulting Limited | Information & communication | 2016 |
| Rankine Rural Limited | Real estate | 2023 |
| RAR (Farming) Limited | Financial services | 2017 |
| Rarecan Limited | Professional & scientific | 2020 |
| RAW Northumberland Limited | Agriculture & fishing | 2024 |
| RB Print Holdings Limited | Financial services | 2026 |
| RB Property Invest Ltd | Construction | 2026 |
| RB Sportscars Ltd | Wholesale & retail | 2022 |
| RBA Bedrooms Ltd | Wholesale & retail | 2025 |
| Rby-Aby Ltd | Professional & scientific | 2019 |
| RC Tree Services Ltd | Agriculture & fishing | 2025 |
| Real Gym Food Ltd | Hospitality | 2025 |
| Reconnaissance Consulting Group Ltd | Information & communication | 2021 |
| Reconnaissance International Limited | Information & communication | 1992 |
| Red Apple Pipefitting Ltd | Construction | 2025 |
| Red Engineering Limited | Construction | 2008 |
| Red Lion Inn Newbrough Limited | Hospitality | 2018 |
| Red Marine (Holdings) Limited | Financial services | 2012 |
| Red Marine EBT Trustee Limited | Professional & scientific | 2020 |
| Red Roof Homes Limited | Real estate | 2020 |
| Rede Valley Trucking Limited | Transport & logistics | 2015 |
| Redesdale Lodges Limited | Extraterritorial | 2017 |
| Redesmouth Investments | Financial services | 2018 |
| Refine Aesthetics NE Ltd | Other services | 2022 |
| Reivers Dynamic Limited | Professional & scientific | 2019 |
| Relin Wholesale Ltd | Wholesale & retail | 2026 |
| Rendez-Vous Dance Ltd | Arts & recreation | 2021 |
| Renwick Estates Ltd | Real estate | 2022 |
| Research on Economic Policy Implementation and Management Limited | Professional & scientific | 1988 |
| Resolution Incorporated Limited | Information & communication | 2018 |
| Retro Rentals Worldwide Ltd. | Administrative & support | 2012 |
| Reversee Ltd | Wholesale & retail | 2020 |
| RF Specialist Joinery Ltd | Manufacturing | 2023 |
| Rhozed LBI Limited | Administrative & support | 2018 |
| RI & MR Ridley Limited | Agriculture & fishing | 2017 |