| Slait Ltd | Information & communication | 2022 |
| Slayford Holdings Ltd | Financial services | 2025 |
| Slim Engine Ltd | Information & communication | 2024 |
| SLR Care Homes Ltd | Health & social care | 2018 |
| Slushhh Monkey Limited | Wholesale & retail | 2025 |
| Smart Choice Kent Limited | Construction | 2014 |
| Smart Home Products Limited | Wholesale & retail | 2012 |
| Smart Property Care Group Ltd | Construction | 2017 |
| SMJ Music Limited | Information & communication | 2012 |
| SMS CIS & Payroll Solutions Ltd | Professional & scientific | 2024 |
| SNA Contracts Ltd | Construction | 2024 |
| SNA Medical Limited | Professional & scientific | 2025 |
| Snaap | Administrative & support | 2009 |
| SO YOU Want to Dance Ltd | Arts & recreation | 2019 |
| Soap FX Limited | Arts & recreation | 2014 |
| Sofast Removals Ltd | Wholesale & retail | 2026 |
| Soft Touch Water Softeners Limited | Construction | 2002 |
| Software Development Solutions Limited | Information & communication | 2012 |
| Solar Specialists Ltd | Construction | 2023 |
| Soorya Limited | Wholesale & retail | 2021 |
| Sophie Curtis Investments Limited | Real estate | 2018 |
| Sophie Curtis Property Limited | Real estate | 1994 |
| Sordfish Ltd | Hospitality | 2022 |
| Soupedup Ltd | Information & communication | 2018 |
| Source Code Control Limited | Information & communication | 2014 |
| South East Excavations Ltd | Construction | 2005 |
| South East Osteopathy Limited | Health & social care | 2018 |
| South East Property Rentals Limited | Real estate | 2023 |
| South East Sealants Limited | Construction | 2019 |
| South East Security Ltd | Construction | 2015 |
| South East Surveys Limited | Professional & scientific | 2014 |
| Southbourne Estates Ltd | Households | 2014 |
| Southern Tyre Recycling Ltd | Water & waste | 2015 |
| SP Engineering Solutions Ltd | Construction | 2007 |
| Spacemaster (Kent) Limited | Administrative & support | 2004 |
| Span Building Services Ltd | Other services | 2018 |
| Speed Europe Ltd | Transport & logistics | 2022 |
| Speedie Consultants Ltd | Administrative & support | 2003 |
| Spektor Group Limited | Information & communication | 2026 |
| Splice Talent Solutions Ltd | Administrative & support | 2025 |
| Sporting Services Limited | Arts & recreation | 2009 |
| Spotlight Press Limited | Information & communication | 2009 |
| SPR Holdings Limited | Administrative & support | 2016 |
| SR Sonography Ltd | Health & social care | 2021 |
| ST Brelades Retirement Homes Limited | Health & social care | 2001 |
| ST George's Dental Laboratory Ltd | Health & social care | 2024 |
| ST Joseph's Convent Preparatory School Gravesend | Education | 2006 |
| ST Peter's Home Limited | Hospitality | 2002 |
| ST. Margaret's Court (Broadstairs) Limited | Households | 1983 |
| Stage Two Mini Cabs Limited | Transport & logistics | 2011 |
| Stakeholder Forum for a Sustainable Future | Other services | 2004 |
| Staplelane Limited | Professional & scientific | 1999 |
| Star Fish Bar Hernbay Ltd | Hospitality | 2020 |
| Starley Compressed Air Limited | Administrative & support | 2011 |
| Start Right Inventories Ltd | Households | 2025 |
| Start Suppliers Limited | Wholesale & retail | 2018 |
| Steadman Brown Limited | Administrative & support | 2017 |
| Steadman Hub Limited | Administrative & support | 2024 |
| Step Stone Accountancy Limited | Professional & scientific | 2019 |
| Sterling Gynaecology GmbH Limited | Health & social care | 2021 |
| Steve Roy's Autos Ltd | Wholesale & retail | 2012 |
| Stevenson Brothers Ltd | Other services | 2025 |
| Stillwater Park Residents Association Limited | Real estate | 2018 |
| Stocks Garage Limited | Wholesale & retail | 1985 |
| Storm - the Joomla Specialists Ltd | Information & communication | 2020 |
| Storm Web Design Ltd | Information & communication | 2012 |
| Story Partners Limited | Information & communication | 2022 |
| Street Motors Ltd | Wholesale & retail | 2017 |
| Stronix Ltd | Construction | 2019 |
| Struck Down Ltd | Information & communication | 2023 |
| Studd Hill Residents Association Ltd | Households | 1937 |
| Stunning Beauty Co Limited | Wholesale & retail | 2019 |
| Stylox Ltd | Professional & scientific | 2018 |
| Sufiscore Ltd | Information & communication | 2020 |
| Sugra Investments Limited | Construction | 2020 |
| SUL4 Limited | Wholesale & retail | 2021 |
| Sun SET Fish Bar Ltd | Hospitality | 2017 |
| Sunny B'Z 2 Ltd | Other services | 2024 |
| Sunset Nails & Beauty Limited | Other services | 2024 |
| Sunshine Thai Spa & Massage Ltd | Health & social care | 2022 |
| Superior Slots Limited | Arts & recreation | 2020 |
| Surefix Construction Company (Kent) Ltd | Construction | 2011 |
| Sustainable Change Consulting LLP | | 2008 |
| SVH Developments Kent Ltd | Construction | 2019 |
| SVH Developments Limited | Construction | 2002 |
| SVH Holdings Ltd | Construction | 2019 |
| Swale Media Arts Centre CIC | Education | 2021 |
| Sweatstop Limited | Arts & recreation | 2023 |
| Sweet Community on the Go C.I.C. | Arts & recreation | 2018 |
| Sweetman Lettings LLP | | 2019 |
| Syed Auto Traders Ltd | Wholesale & retail | 2025 |
| Syllables Ltd | Education | 2023 |
| Synapse Solutions Ltd | Education | 2020 |
| Syncly Consulting Ltd | Information & communication | 2020 |
| System Clad (Specialist Works) Limited | Administrative & support | 1999 |
| T & S Read Ltd | Real estate | 2017 |
| T & T Ward Limited | Wholesale & retail | 2011 |
| T D Robinson Heating & Plumbing Limited | Construction | 2007 |
| T F Mather Limited | Health & social care | 2025 |
| T J Tiling Ltd | Construction | 2020 |