| S & D London Properties Limited | Real estate | 2019 |
| S & D Property Management Limited | Real estate | 2009 |
| S & M 247 Care Limited Limited | Administrative & support | 2025 |
| S a Cameron PO Limited | Construction | 2023 |
| S G Security Installations Limited | Administrative & support | 2007 |
| S J Watt Tiling Ltd | Construction | 2015 |
| S K L Construction & Design Ltd | Construction | 2015 |
| S M ROW Electrical Engineers Limited | Construction | 2013 |
| S Murphy Recruitment Services Ltd | Administrative & support | 2024 |
| S R Smith Electrical Limited | Construction | 2017 |
| S&D Northcircular Limited | Real estate | 2020 |
| S&I Keefe Ltd | Real estate | 2025 |
| S&I Property Management Ltd | Real estate | 2025 |
| S&L Builders Ltd | Construction | 2018 |
| S&N Barbers Ltd | Other services | 2024 |
| S&Y Developers Ltd | Construction | 2020 |
| S-Martmoney Skills Community Interest Company | Education | 2020 |
| S.B Gymnastics Ltd | Arts & recreation | 2024 |
| S.C.S. Hotline Limited | Health & social care | 2005 |
| S.Chapman Property Services Ltd | Construction | 2003 |
| S.E.O. Construction Ltd | Construction | 2019 |
| S.L.H. Communications Ltd. | Professional & scientific | 2010 |
| S.S.C Courier Limited | Transport & logistics | 2025 |
| S.T. Windows Doors & Conservatories Ltd | Construction | 2018 |
| S.T.I. (U.K.) Limited | Transport & logistics | 1995 |
| S.T.M. Limited | Wholesale & retail | 1990 |
| S.W.A.T Design & Build Limited | Construction | 2018 |
| S2M Limited | Administrative & support | 2007 |
| S:23 Recruitment Ltd | Administrative & support | 2024 |
| SA Catering Ltd | Hospitality | 2015 |
| SAA Designs Limited | Wholesale & retail | 2020 |
| Saac Services Limited | Real estate | 2016 |
| Saban-Uk 16 Limited | Transport & logistics | 2016 |
| Sable Projects Limited | Construction | 2015 |
| SAC Luton Ltd | Wholesale & retail | 2025 |
| Saddlers Wharf (Walsall) Management Company Limited | Households | 2002 |
| Safe Care 24/7 Limited | Health & social care | 2017 |
| Safe Frame Scaffolding Limited | Construction | 2025 |
| Safe Hands Professional Services Limited | Administrative & support | 2026 |
| Safe Height Scaffolding Ltd | Construction | 2021 |
| Safe Platform Services Limited | Construction | 2025 |
| Safedent(Uk) Limited | Information & communication | 2019 |
| Saferoute Logistics Ltd | Transport & logistics | 2026 |
| Safeseal Limited | Construction | 2002 |
| Safetech Solutions Ltd | Construction | 2024 |
| Safety Certification Limited | Administrative & support | 1999 |
| Safety HUT Limited | Administrative & support | 2008 |
| Saffire Systems Ltd | Transport & logistics | 2015 |
| Saffron Express Ltd | Extraterritorial | 2020 |
| Saffron Harvey Investments Limited | Financial services | 2024 |
| Saffron Harvey Property Management Limited | Real estate | 2020 |
| Saffron Hemel Ltd | Hospitality | 2024 |
| Sahasra Overseas UK Ltd | Transport & logistics | 2025 |
| Sahra Deli̇very and Technical Service Ltd | Wholesale & retail | 2026 |
| Saic Limited | Construction | 2023 |
| Saints View (Redhill) Management Company Limited | Households | 2022 |
| Saivasista Ltd | Hospitality | 2026 |
| Salatch Ltd | Manufacturing | 2000 |
| Salcombe Regis Holiday Park Limited | Arts & recreation | 2025 |
| Sales Shop Ltd | Financial services | 2020 |
| Salestv Ltd | Professional & scientific | 2023 |
| Saletype Limited | Real estate | 1994 |
| Saliev Ltd | Construction | 2015 |
| Salix Mechanical Ltd | Energy | 2023 |
| Salix Mechanical Services LLP | | 2011 |
| Sally Gunner Limited | Information & communication | 2013 |
| Salt & Smoke Events Limited | Hospitality | 2026 |
| Sammakescode Limited | Information & communication | 2018 |
| Samphire Meadow Residents Management Company Limited | Households | 2022 |
| Samta Consulting Limited | Information & communication | 2007 |
| Samuel Flood Ltd | Information & communication | 2019 |
| SAN Giorgio Pizzeria Ltd | Hospitality | 2021 |
| Sanders Property Management Limited | Real estate | 2011 |
| Sandford Paddocks (Blackmore) Limited | Households | 2020 |
| Sandhills Property Management Limited | Real estate | 1996 |
| Sandpiper Place (Apartments) Management Company Limited | Households | 2009 |
| Sandridge Place (Melksham) Management Company Limited | Households | 2018 |
| Sandwich Sorted Ltd | Hospitality | 2015 |
| Sandy Balls Estate Limited | Hospitality | 1959 |
| Sanko Limited | Administrative & support | 2013 |
| Sann Property Limited | Construction | 2017 |
| Sanseverino Productions Ltd | Construction | 2025 |
| Sanseverinos Construction Ltd | Construction | 2024 |
| Santuary Support Limited | Health & social care | 2013 |
| Sapphire Roofing & Construction Ltd | Construction | 2022 |
| Saracut Logistics Ltd | Transport & logistics | 2026 |
| Sarah Parkins Academy Ltd | Education | 2023 |
| Sarah WG Ltd | Professional & scientific | 2019 |
| Saranne Estates Limited | Real estate | 2012 |
| Saraz Auto Exports Ltd | Wholesale & retail | 2025 |
| Sarican Ltd | Hospitality | 2023 |
| SAS Concepts Limited | Construction | 2024 |
| Sassi Drinks Ltd | Manufacturing | 2025 |
| SAT Space Ltd | Real estate | 2024 |
| Sathyam Management PVT Ltd | Hospitality | 2020 |
| Saturn House Freeholders Limited | Households | 2018 |
| Sauce Code Ltd | Information & communication | 2015 |
| Saunderson Gardens Management Co Ltd | Households | 2006 |
| Savage Entertainment & Trading Ltd | Hospitality | 2025 |
| Savage Property Holdings Ltd | Real estate | 2025 |