| TW Services (North East) Ltd | Construction | 2020 |
| Tyler, Robson and DON Building Services Ltd | Construction | 2019 |
| Tyne & Wear Consultancy Services Ltd | Professional & scientific | 2024 |
| Tyne and Wear Access NE Ltd | Administrative & support | 2013 |
| Tyne Travel Ltd | Administrative & support | 2021 |
| Tynemouth Turkish Barber Ltd | Other services | 2019 |
| Tyneside Futsal Club Ltd | Administrative & support | 2013 |
| Tyneside Quality Pizza Limited | Hospitality | 2022 |
| UK Firewatch Limited | Construction | 1991 |
| Ultraclean Pro Services Limited | Administrative & support | 2026 |
| Uniquej Ltd | Wholesale & retail | 2023 |
| Unleashed Dog Grooming Ltd | Other services | 2020 |
| Ventilation Supplies Limited | Energy | 2005 |
| Verdun Holdings Ltd | Financial services | 2023 |
| Vetreach Ltd | Professional & scientific | 2025 |
| Viking Coaching Services Ltd | Other services | 2022 |
| Viking Gym & Supplements Ltd | Wholesale & retail | 2022 |
| Viking Gym Ltd | Arts & recreation | 2019 |
| Viking Scaffolding North East Limited | Construction | 2014 |
| Village Property Services Ltd | Construction | 2025 |
| Viva Mini Market Ltd | Wholesale & retail | 2026 |
| VIZ Analytics Limited | Information & communication | 2021 |
| VN Design Ltd | Professional & scientific | 2019 |
| VOS (Sports) Limited | Wholesale & retail | 2022 |
| W.J. Bell (Orbital) Ltd | Professional & scientific | 2014 |
| Waggy Wanderers Ltd | Other services | 2024 |
| Wardles Pool Ltd | Hospitality | 2020 |
| Water Site Management Services Limited | Construction | 2017 |
| WE ALL Beam Limited | Other services | 2022 |
| Websalesandleasing Limited | Information & communication | 1998 |
| Wentbridge Property Ltd | Real estate | 2026 |
| West Park Property Group Ltd | Real estate | 2022 |
| Whitelake Properties North East Ltd | Real estate | 1998 |
| Whites Hair Design Limited | Other services | 2022 |
| Willumsen GAS Heating & Boiler Solutions Ltd | Construction | 2025 |
| Windmill Sustainable Business Solutions Limited | Water & waste | 2004 |
| Wioh Ltd | Information & communication | 2017 |
| Word Expert Limited | Information & communication | 2023 |
| Worship Media Solutions Limited | Information & communication | 2023 |
| Wright Offshore Ltd | Professional & scientific | 2026 |
| Ww&B Investments LLP | | 2007 |
| Xin&Ping Ltd | Real estate | 2025 |
| Youngs Proactive Welding Inspection Services Ltd | Manufacturing | 2011 |
| Your Accountants NE Limited | Professional & scientific | 2024 |
| Yvettes Deli A'Mour Ltd | Hospitality | 2024 |
| Zenith Training Limited | Administrative & support | 2015 |
| Zetadisplay UK Holdings Limited | Financial services | 2019 |
| Zetadisplay UK Limited | Information & communication | 2011 |