| Elaine Parkes Solicitors Ltd | Professional & scientific | 2014 |
| Elaine Towell Ltd | Professional & scientific | 2022 |
| Elas Cafe Ltd | Hospitality | 2022 |
| Elayess Ltd | Education | 2025 |
| ELC Plumbing & Heating Limited | Construction | 2006 |
| Electric Palace Cinema C.I.C. | Information & communication | 2012 |
| Electric Piers CIC | Information & communication | 2022 |
| Electrokemp Ltd | Manufacturing | 2020 |
| Elektrik Ltd | Professional & scientific | 2024 |
| Elements in Motion CIC | Manufacturing | 2025 |
| Elena Popa Photography Ltd | Professional & scientific | 2023 |
| Elevation Business Finance Ltd | Professional & scientific | 2026 |
| Eligrade Ltd | Wholesale & retail | 2025 |
| Elliott Drywall Limited | Construction | 2013 |
| Elsie’S Mini Mart Limited | Wholesale & retail | 2024 |
| Elysian Homes & Properties Ltd | Real estate | 2025 |
| EMA Private Finance Limited | Financial services | 2019 |
| Embark Ltd | Health & social care | 2010 |
| Embassy House Limited | Households | 2000 |
| Ember Architecture Ltd | Professional & scientific | 2026 |
| Ember Tides Ltd | Manufacturing | 2023 |
| Emdair Limited | Energy | 1984 |
| Emergency Life Support Team Limited | Health & social care | 2011 |
| Emibaz Ltd | Wholesale & retail | 2025 |
| Emma Atkinson Management Ltd | Administrative & support | 2024 |
| Emme Ltd | Hospitality | 2025 |
| Emmys Removals Limited | Transport & logistics | 2020 |
| Empirical Events Limited | Administrative & support | 2015 |
| Empirical Venue Marketing Ltd | Administrative & support | 2023 |
| EMS Access Specialists Limited | Construction | 2024 |
| Endgrain Holdings Limited | Financial services | 2021 |
| Enhance Plastering and Rendering Ltd | Construction | 2023 |
| Enjoycation C.I.C. | Education | 2018 |
| Ennas & Saunders LLP | | 2025 |
| Enriched Content Services Limited | Information & communication | 2026 |
| Ensemble Orquesta | Arts & recreation | 2020 |
| Ensign Court (Hastings) Management Company Limited | Households | 1974 |
| Entertainment Workshops Limited | Education | 2011 |
| Epicbite Kitchens Ltd | Hospitality | 2025 |
| Epicus International Limited | Administrative & support | 2019 |
| Equilibrium Business Solutions Ltd | Administrative & support | 2012 |
| Equilibrium Fires and Fireplaces Ltd | Wholesale & retail | 2024 |
| Equnox Limited | Wholesale & retail | 2023 |
| Erol's Kebab Limited | Hospitality | 2021 |
| ES Fire Solutions Ltd | Construction | 2026 |
| ESK Wholesale (Holdings) Limited | Financial services | 2024 |
| ESP Rail Ltd | Construction | 2014 |
| Essential Hygiene Services Ltd | Administrative & support | 2026 |
| ET Pursuits Limited | Administrative & support | 2016 |
| Eternal Love Limited | Wholesale & retail | 2011 |
| Evanic Ltd | Wholesale & retail | 2025 |
| Evatt Industries Ltd. | Information & communication | 1998 |
| Evatt Risk Ltd. | Information & communication | 2024 |
| Eveline Tijs Consulting Ltd | Health & social care | 2023 |
| Everalo Ltd | Wholesale & retail | 2025 |
| Everstone Exteriors Ltd | Construction | 2026 |
| Every Little Thing (South East) Ltd | Health & social care | 2023 |
| Evexia Lifecare Africa Limited | Construction | 2022 |
| Evmt Progress Limited | Professional & scientific | 2013 |
| Evocatus Limited | Public administration | 2026 |
| Excellium Solutions Ltd | Information & communication | 2022 |
| Exclusive Aesthetic Limited | Other services | 2016 |
| Exiges Auto Ltd | Wholesale & retail | 2019 |
| Expert Joinery (Sussex) Ltd | Construction | 2019 |
| Eyemasters Ltd | Professional & scientific | 2016 |
| F & H Management Limited | Professional & scientific | 2014 |
| F Chambers Limited | Wholesale & retail | 2008 |
| Facilis (London) Ltd | Administrative & support | 2016 |
| Faffless Technology Limited | Information & communication | 2020 |
| Fagin's Old Town Limited | Hospitality | 2018 |
| Fairbrother Agency Ltd | Professional & scientific | 2023 |
| Fairlight Advisors Ltd | Arts & recreation | 2025 |
| Fairlight Carpentry Ltd | Construction | 2023 |
| Fairlight Gardens Freehold Limited | Real estate | 1997 |
| Fairlight Therapy Ltd | Health & social care | 2019 |
| Fairline HR Consultancy Ltd | Administrative & support | 2025 |
| Fairstart Ltd | Information & communication | 2016 |
| Fairstone Court (Hastings) Management Company Limited | Households | 2000 |
| Fanan Ltd | Wholesale & retail | 2025 |
| Faris Diagnostics Limited | Health & social care | 2011 |
| Farriers View Residents Limited | Households | 2023 |
| Fastfix Contruction Ltd | Construction | 2026 |
| Fastlanegb Ltd | Wholesale & retail | 2023 |
| Faythos Trade Limited | Wholesale & retail | 2026 |
| Fbaj Property Holdings Ltd | Real estate | 2024 |
| Fellows Road Management (2021) Limited | Households | 2021 |
| Fenix Construction Limited | Construction | 2015 |
| Fester Fang Creations Ltd | Wholesale & retail | 2024 |
| FHA Contractors Limited | Real estate | 2022 |
| Field Boutiques Ltd | Wholesale & retail | 2024 |
| Fieldco Hire Ltd | Administrative & support | 2026 |
| Filo Films Ltd | Information & communication | 2021 |
| Fine Architecture Ltd | Professional & scientific | 2006 |
| Fine Developments Ltd | Professional & scientific | 1973 |
| Finish Studio Ltd | Construction | 2025 |
| Fink Technologies Ltd | Information & communication | 2025 |
| Firmlawns Property Management Limited | Real estate | 1991 |
| First Choice Mortgages (Sussex) Limited | Financial services | 2003 |
| First Choice Mortgages and Financial Ltd | Financial services | 2025 |
| First Choice Properties (Sussex) Limited | Real estate | 2016 |