| Rayan Mini Market (NE) Ltd | Wholesale & retail | 2025 |
| Rayans Mini Market Ltd | Wholesale & retail | 2026 |
| Rays Stores Ltd | Wholesale & retail | 2020 |
| Rayyan International Links Ltd | Wholesale & retail | 2023 |
| Razzak Holding Ltd | Financial services | 2026 |
| RCD Property Developments (NE) Ltd | Construction | 2021 |
| RCD Property Management Ltd | Real estate | 2020 |
| RCL Project Services Ltd | Professional & scientific | 2024 |
| Rcnb Construction Limited | Construction | 2019 |
| RD Dryden Limited | Agriculture & fishing | 2022 |
| RDM Hair, Beauty & Wellness Products and Services Limited | Wholesale & retail | 2022 |
| RDM Healthcare Services Limited | Health & social care | 2022 |
| RDM Pooku Foods Limited | Wholesale & retail | 2026 |
| Rdpeart Electrical Ltd | Construction | 2024 |
| RE LS Enterprises Limited | Arts & recreation | 2025 |
| Reactive Design Agency Limited | Professional & scientific | 2010 |
| Readhead Associates Limited | Other services | 2015 |
| Real Pizzamatic Ltd | Hospitality | 2019 |
| Reaon Group Ltd | Manufacturing | 2024 |
| Rebecca Hand Ltd | Financial services | 2023 |
| Rebecca Jakob Consulting Ltd | Professional & scientific | 2019 |
| Rebecca Melanie Evans Ltd | Extraterritorial | 2022 |
| Recruit Studio Limited | Information & communication | 2012 |
| Red Spade Limited | Professional & scientific | 2011 |
| Redcar Eats Limited | Hospitality | 2024 |
| Redden Civil Engineering Services Ltd | Construction | 2016 |
| Redline Transport Limited | Transport & logistics | 1982 |
| Redmoon Global Services Limited | Administrative & support | 2007 |
| Reed & Co Electrical Ltd | Construction | 2025 |
| Reem's Pizzeria Limited | Wholesale & retail | 2024 |
| Reflection Room Therapy Service Ltd | Health & social care | 2025 |
| Reflekta Ltd | Administrative & support | 2025 |
| Refresh Aesthetics by ALY Ltd | Health & social care | 2024 |
| Regency Consultancy (North East) Ltd | Construction | 2011 |
| Regency Finance Ltd | Financial services | 2020 |
| Rekha Ltd | Health & social care | 2016 |
| Reklaw-Uk Ltd | Information & communication | 2002 |
| Remilton Convenience Limited | Wholesale & retail | 2024 |
| Remilton Convenient Store Limited | Wholesale & retail | 2016 |
| Remote Power Quality Ltd | Professional & scientific | 2019 |
| Rendocs Design Limited | Administrative & support | 2012 |
| Renewable Energy Project Solutions Ltd | Professional & scientific | 2020 |
| Renewable Energy Subsea Services Limited | Mining & quarrying | 2011 |
| Renline Motors Limited | Wholesale & retail | 2021 |
| Renovato Solution Group Ltd | Professional & scientific | 2025 |
| Renovise Interiors Ltd | Construction | 2024 |
| Renters Rights ACT 2026 Ltd | Professional & scientific | 2026 |
| Repair 4 Profit Limited | Professional & scientific | 2004 |
| Reply Done Ltd | Information & communication | 2025 |
| Residents of Station Road Greatham Limited | Administrative & support | 2015 |
| Resiprop Invest Ltd | Real estate | 2021 |
| Resolved Group Limited | Information & communication | 2024 |
| Retaining (UK) Limited | Construction | 2016 |
| Retro Motorcycle Spares Limited | Wholesale & retail | 2023 |
| Revolution Investments Ltd | Real estate | 2023 |
| Revolution Surveys Ltd | Professional & scientific | 2022 |
| RH Jointing Services Ltd | Construction | 2018 |
| RH Marine UK Ltd | Manufacturing | 1996 |
| RH Project Consulting Ltd | Professional & scientific | 2025 |
| RH Technician Ltd | Construction | 2022 |
| Rhodes Planning & Production Control Limited | Information & communication | 2005 |
| Rhodium Property Management Ltd | Real estate | 2019 |
| Rhythmic Marketing Limited | Information & communication | 2011 |
| Ricco Limited | Wholesale & retail | 2003 |
| Richard Petch Associates Limited | Extraterritorial | 2003 |
| Richardson Financial Services Limited | Professional & scientific | 2013 |
| Rickety Bridge Productions Ltd | Arts & recreation | 2018 |
| Ridco Ltd | Construction | 2025 |
| Ridgmont Services Ltd | Wholesale & retail | 2018 |
| Ridings Trading Ltd | Hospitality | 2024 |
| Rieder Investments Limited | Real estate | 2019 |
| Rieder Wellness Ltd | Health & social care | 2011 |
| Rigtrainingprograms Limited | Other services | 2023 |
| Riley Inspection Services Limited | Professional & scientific | 2017 |
| Riley Property and Accommodation Limited | Real estate | 2021 |
| RIP N Go Limited | Water & waste | 2025 |
| Rito Properties Limited | Real estate | 2023 |
| RIVALS3D Ltd | Manufacturing | 2025 |
| Riverside Management Company (Middlesbrough) Limited | Real estate | 2014 |
| Rivisio Limited | Information & communication | 2025 |
| RIX Decor Ltd | Construction | 2017 |
| RJB Property Management Limited | Real estate | 2019 |
| RJD ANP Services Ltd | Public administration | 2023 |
| RJH Technical Solutions Ltd | Professional & scientific | 2015 |
| Rjms Leisure Ltd | Arts & recreation | 2025 |
| RJS Inspections Ltd | Construction | 2025 |
| RK Adventures Ltd | Agriculture & fishing | 2023 |
| Rkgroupuk Ltd | Real estate | 2026 |
| Rkrbuilders Ltd | Construction | 2025 |
| RLB International Limited | Administrative & support | 2016 |
| RM Entertainment Limited | Arts & recreation | 2024 |
| RM Lifting & Rigging Limited | Construction | 2025 |
| Roam and Away Ltd | Real estate | 2021 |
| Roaring Mouse Community Interest Company | Arts & recreation | 2007 |
| Roberts EYE Care Hartlepool Limited | Health & social care | 2017 |
| Robinson & Family Properties Limited | Real estate | 2025 |
| Robinson and Robinson Hospitality Limited | Hospitality | 2023 |
| Robinson House Business Centre C.I.C. | Real estate | 2024 |
| Robinson Hvpd Ltd | Professional & scientific | 2023 |
| Robinson Pipework Services Ltd | Manufacturing | 2014 |