| Dellab Consulting Limited | Information & communication | 2015 |
| Delroy Smith Master Tailor Ltd | Other services | 2021 |
| Deltech Consulting Limited | Information & communication | 2018 |
| Delutrans Ltd | Wholesale & retail | 2018 |
| Delvis Contractors Limited | Construction | 2012 |
| Demidoyle Limited | Health & social care | 2015 |
| Demir Estate Ltd | Real estate | 2026 |
| Demmzybol Ltd | Health & social care | 2023 |
| Denby Building Services Ltd | Construction | 2021 |
| Dencon Accessories Limited | Wholesale & retail | 1965 |
| Denis Sport MGT Ltd | Extraterritorial | 2021 |
| Denizgok Limited | Wholesale & retail | 2018 |
| Dennis-Raymond Thomas Ltd | Extraterritorial | 2024 |
| DEO Provincia Limited | Professional & scientific | 2007 |
| Deplenty Concepts Limited | Real estate | 2022 |
| Derinadrex Limited | Health & social care | 2013 |
| Derrick Wade Waters Holdings Ltd | Real estate | 2015 |
| Derrick Wade Waters Ltd | Real estate | 1995 |
| Design Corp. Ltd | Professional & scientific | 2003 |
| Design Well Digital Services Limited | Information & communication | 2019 |
| Designutions Ltd | Information & communication | 2023 |
| Desmondfresh Limited | Health & social care | 2023 |
| Desserts to Home Limited | Hospitality | 2025 |
| Destello Tech Ltd | Wholesale & retail | 2025 |
| Destination Law Limited | Professional & scientific | 2022 |
| Destined Events Ltd | Other services | 2025 |
| Destiny Creative Ltd | Manufacturing | 2024 |
| Destinyshapers Training & Consultancy Ltd | Professional & scientific | 2026 |
| Detak Limited | Health & social care | 2022 |
| Deux Hall Limited | Administrative & support | 2002 |
| Develop-X Ltd | Construction | 2022 |
| Development and Delivery Services Limited | Construction | 2018 |
| Development Governance Consult Ltd | Health & social care | 2018 |
| Devereux Fisher Consulting Ltd | Professional & scientific | 2023 |
| Devine Sound Service Ltd | Information & communication | 2023 |
| Devohseven Ltd | Professional & scientific | 2024 |
| Devonshire House Freehold Management Limited | Households | 2004 |
| Dexigent Contractor Ltd | Information & communication | 2016 |
| Dexigent Properties Limited | Real estate | 2024 |
| Dexmax Accountants Ltd | Professional & scientific | 2020 |
| Dexters Law Limited | Professional & scientific | 2023 |
| Dezybrown Services Ltd | Health & social care | 2019 |
| Dfold LAB Limited | Information & communication | 2025 |
| DG Health Services Ltd | Health & social care | 2021 |
| DGF Andrei Ltd | Construction | 2023 |
| DGS Consulting Limited | Information & communication | 2024 |
| DGS Supply Chain Ltd | Professional & scientific | 2013 |
| Dhcc Consultancy Limited | Public administration | 2021 |
| DHM International UK Ltd | Wholesale & retail | 2017 |
| Diabetes Africa Limited | Administrative & support | 2019 |
| Diaclan Limited | Health & social care | 2024 |
| Diadem Estate Limited | Real estate | 2022 |
| Diamond Konsultants Ltd | Information & communication | 2017 |
| Diamond Painters Limited | Construction | 2023 |
| Diamond Sphinx Limited | Hospitality | 2023 |
| Diamond Touch Limited | Real estate | 2017 |
| Diamond Unique Care Limited | Health & social care | 2014 |
| Diane Bakemhe Limited | Financial services | 2012 |
| Diatrans Limited | Transport & logistics | 2024 |
| Didgemere Farms Limited | Real estate | 1997 |
| Difan Medicals Ltd | Health & social care | 2025 |
| Difyjobs Ltd | Construction | 2019 |
| Digidiamond Group Ltd | Wholesale & retail | 2018 |
| Digisec Solutions Ltd | Information & communication | 2021 |
| Digiss Limited | Information & communication | 2022 |
| Digit Design Studios Ltd | Wholesale & retail | 2026 |
| Digital Demon Ltd | Information & communication | 2019 |
| Digital Imaging (UK) Limited | Transport & logistics | 2000 |
| Dihealth Limited | Health & social care | 2022 |
| Diksha Surani Ltd | Health & social care | 2023 |
| Diliken Healthcare Limited | Health & social care | 2022 |
| Dillords Limited | Wholesale & retail | 2016 |
| Dimason Ltd | Other services | 2025 |
| Dimex Limited | Financial services | 1983 |
| Dimra Investment Ltd | Real estate | 2020 |
| DINKO2000 Ltd | Construction | 2018 |
| Direct Barriers Limited | Professional & scientific | 2009 |
| Direct Window & Door Repairs Ltd | Construction | 2026 |
| Directdisplays Limited | Construction | 2001 |
| Dirichlet Consulting and Services Limited | Information & communication | 2011 |
| Dirnalogistics Ltd | Transport & logistics | 2022 |
| Discipleship-Solutions Ltd | Information & communication | 2018 |
| Disco Media Ltd | Professional & scientific | 2024 |
| Discount Home Improvements Limited | Construction | 2017 |
| Distribution Maintenance Consultancy Limited | Professional & scientific | 2020 |
| Distribution Maintenance Limited | Professional & scientific | 2006 |
| Dive Logistics Ltd | Transport & logistics | 2012 |
| Diveal Medical Services Ltd | Health & social care | 2025 |
| Divine Encounters Ltd | Health & social care | 2022 |
| Divinedew Varieties Ltd | Wholesale & retail | 2025 |
| Divstech Ltd | Wholesale & retail | 2024 |
| DJ Geoservices Ltd. | Professional & scientific | 2019 |
| DJ Mista MR Limited | Arts & recreation | 2022 |
| Djansan Ltd | Health & social care | 2015 |
| DJB Build Ltd | Construction | 2025 |
| DJB Global Limited | Real estate | 2013 |
| DJC Auto's Limited | Wholesale & retail | 2012 |
| DJC Holdings Essex Ltd | Real estate | 2023 |
| DJF Rail Services Limited | Construction | 2014 |
| DJM Fire Limited | Administrative & support | 2023 |