| Daisy Grace Designs Limited | Extraterritorial | 2011 |
| Daisy Wellness Ltd | Administrative & support | 2023 |
| Dajaak Health Ltd | Health & social care | 2025 |
| Daken Consulting Limited | Information & communication | 2012 |
| Dakos Stone Ltd | Transport & logistics | 2017 |
| Dali Enterprises Ltd | Health & social care | 2020 |
| Dalisebel Ltd | Health & social care | 2018 |
| Damarket Ltd | Professional & scientific | 2025 |
| Damure Limited | Health & social care | 2025 |
| Dandy Detailing Ltd | Administrative & support | 2026 |
| Daneko Ltd | Construction | 2018 |
| Danen Healthcare Limited | Health & social care | 2018 |
| Daneoson Ltd | Health & social care | 2020 |
| Dani King PT Ltd | Extraterritorial | 2022 |
| Daniel Green Wealth Management Limited | Financial services | 2017 |
| Daniel Thomas Estates Ltd | Real estate | 2020 |
| Daniel Wasilewski Cars Limited | Wholesale & retail | 2018 |
| Danielle Bailey Hair Ltd | Other services | 2026 |
| Danisan Limited | Health & social care | 2025 |
| Danjerrys Limited | Administrative & support | 2020 |
| Danjola Limited | Health & social care | 2016 |
| Dannez Ltd | Professional & scientific | 2014 |
| Danny Cadman Ltd | Construction | 2014 |
| Dannymore Limited | Health & social care | 2017 |
| Danuel Limited | Health & social care | 2016 |
| Dapijo Medics Ltd | Health & social care | 2025 |
| Dapper Dust Busters Limited | Administrative & support | 2024 |
| Daren Consultant Limited | Professional & scientific | 2015 |
| Darfem Limited | Health & social care | 2026 |
| Dark Path Grappling Ltd | Arts & recreation | 2024 |
| Darka Daro Ltd | Administrative & support | 2019 |
| Darya Trans Limited | Transport & logistics | 2017 |
| Dasheys Cleaning Solutions Limited | Households | 2020 |
| Dashika Limited | Manufacturing | 2019 |
| Dasi Food Hub Ltd | Hospitality | 2025 |
| Dataglen Limited | Real estate | 1981 |
| Datalinksng Ltd | Information & communication | 2022 |
| Dataspec Ltd | Information & communication | 2021 |
| Davansa Limited | Transport & logistics | 2025 |
| David Drew Canine Behaviourist Limited | Professional & scientific | 2021 |
| David Hogg Consultancy Ltd | Professional & scientific | 2025 |
| David Marshall Consultancy Limited | Professional & scientific | 2013 |
| David Owusu Ministries Ltd | Other services | 2020 |
| David WEJ UK Limited | Wholesale & retail | 2020 |
| Davidbrother Construction Limited | Construction | 2021 |
| Davidite Limited | Information & communication | 2021 |
| Davies Harvey and Murrell Group Limited | Wholesale & retail | 1982 |
| Davies,Harvey & Murrell Limited | Wholesale & retail | 1919 |
| Davinstone Limited | Professional & scientific | 2018 |
| Davlave Limited | Construction | 2019 |
| Davoniy Investments Ltd | Real estate | 2020 |
| Davwels Limited | Health & social care | 2023 |
| Daystrom Systems Ltd | Information & communication | 2011 |
| Dayton Global Ltd | Hospitality | 2024 |
| DB Talent Ltd | Professional & scientific | 2026 |
| DB2 Plumbing & Heating LLP | | 2015 |
| DBI Trading Ltd | Administrative & support | 2012 |
| Dbill Ltd | Information & communication | 2020 |
| DC Rail Limited | Administrative & support | 2012 |
| DCC Global Solutions Limited | Professional & scientific | 2021 |
| DCK Fashions Limited | Manufacturing | 2024 |
| DCM - Domestic Commercial Maintenance Ltd | Construction | 2015 |
| DCM Kozak Property Ltd | Households | 2024 |
| DCW Citadel Ltd | Financial services | 2026 |
| DCY Phenix Limited | Construction | 2021 |
| DD Painting Ltd | Construction | 2018 |
| DDH Home Improvements Ltd | Construction | 2019 |
| Ddoye Properties Limited | Real estate | 2024 |
| DE Burgh Close (Broxbourne) Management Company Limited | Households | 2012 |
| DE Cherished Pro Limited | Wholesale & retail | 2026 |
| DE Gorgeous by EWA Limited | Wholesale & retail | 2023 |
| DE Lacy Fields KM8 Management Company Limited | Households | 2015 |
| DE Mandeville Court Management Company Limited | Households | 1988 |
| De-Balm Urology Services Limited | Health & social care | 2024 |
| Deal Grupe Ltd | Information & communication | 2025 |
| Deals Dropzone Limited | Wholesale & retail | 2023 |
| Dealtrak Ltd | Information & communication | 2003 |
| Deano's Property Maintenance Limited | Construction | 2020 |
| Debbie Ltd | Health & social care | 2023 |
| Debden Barns Day Nursery Ltd | Health & social care | 2025 |
| Debeloved Consulting Limited | Professional & scientific | 2024 |
| Deblev Properties Limited | Real estate | 2022 |
| Deblis Events Limited | Hospitality | 2025 |
| Debo Health Limited | Health & social care | 2025 |
| Decahedron Ltd | Wholesale & retail | 2011 |
| Deciphr Ltd | Professional & scientific | 2019 |
| Decor 88 Ltd | Construction | 2018 |
| Decoralin Ltd | Manufacturing | 2021 |
| Decruz Holdings Limited | Health & social care | 2025 |
| Dedhu Ltd | Wholesale & retail | 2024 |
| Deejay Property Group Ltd | Real estate | 2021 |
| Deejoe Coxy Homes Ltd | Real estate | 2024 |
| Deejoe Ltd | Real estate | 2023 |
| DEEN2DEEN Limited | Public administration | 2025 |
| Defroscia Close Management Company Limited | Households | 2019 |
| Deimante Properties Ltd | Real estate | 2023 |
| Deka Finishes Ltd | Construction | 2025 |
| Delez-Uk Ltd | Construction | 2020 |
| Delightcare Homes Ltd | Administrative & support | 2021 |
| Delivra AI Limited | Information & communication | 2026 |