| European Student Developments Ltd | Hospitality | 2020 |
| European Work Experience Programme Ltd | Administrative & support | 1995 |
| Eurostar Grimsby Supermarket Ltd | Wholesale & retail | 2026 |
| Eurotax Connect Ltd | Information & communication | 2025 |
| EVA SRL Limited | Transport & logistics | 2025 |
| Evacado.Co.Uk Ltd | Energy | 2022 |
| Evaluate 2000 Limited | Wholesale & retail | 2008 |
| Evan Barber Ltd | Other services | 2026 |
| Evans European Transport Holdings Limited | Financial services | 2025 |
| Evans European Transport Limited | Transport & logistics | 2015 |
| Evans Safety Management Limited | Other services | 2017 |
| Event Crew Solutions Limited | Administrative & support | 2014 |
| Event Hero Ltd | Professional & scientific | 2019 |
| Event Kitchens Limited | Administrative & support | 2013 |
| Event Show Support C.I.C. | Administrative & support | 2014 |
| Eventure North Ltd | Administrative & support | 2025 |
| Ever Music Group Limited | Information & communication | 2024 |
| Evergreen Eco Solutions Ltd | Construction | 2024 |
| Evershine Grimsby Ltd | Construction | 2026 |
| EVO Academy CIC | Other services | 2020 |
| Evolution Compliance and Management Solutions Ltd | Information & communication | 2016 |
| Evolution DRY Ice Limited | Wholesale & retail | 2023 |
| Evolution GAS Solutions Ltd. | Construction | 2017 |
| Evolve Wealth Limited | Financial services | 2010 |
| Ewep Property Assets Management Ltd. | Real estate | 1998 |
| EWS EOT Trustee Limited | Other services | 2023 |
| EXA Truck Ltd | Transport & logistics | 2023 |
| Exceed Logistics Limited | Transport & logistics | 2009 |
| Excell Engineering (Grimsby) Limited | Manufacturing | 2004 |
| Excellent Seafoods of Grimsby Limited | Wholesale & retail | 2002 |
| Excelsior Fishing Company Limited | Agriculture & fishing | 1999 |
| Exciting Foods Limited | Manufacturing | 1999 |
| Exotics of the World Encounters Ltd | Education | 2019 |
| Exotics of the World Ltd | Wholesale & retail | 2015 |
| Expanse (Bridlington) Limited(The) | Hospitality | 1937 |
| Expert Paving Limited | Construction | 2003 |
| Expert Renovations Limited | Construction | 2024 |
| Expert Spray Limited | Construction | 2023 |
| Explore More Adventures Ltd | Wholesale & retail | 2019 |
| Explorosity Education Limited | Education | 2019 |
| Expo Data Comms Limited | Information & communication | 2007 |
| Express Medical Personnel Ltd | Administrative & support | 2016 |
| Express Seafoods (East Coast) Limited | Wholesale & retail | 2025 |
| Express Seafoods (GY) Limited | Wholesale & retail | 2012 |
| Extraction Carpet Cleaning Ltd | Other services | 2025 |
| Extraction Cleaning Limited | Administrative & support | 2024 |
| Extraction Exterior Cleaning Ltd | Other services | 2025 |
| Extranjero Ltd | Hospitality | 2021 |
| Extraordinary World Limited | Wholesale & retail | 2013 |
| Extreme Cargo Ltd. | Transport & logistics | 2015 |
| Extrzoom International Limited | Wholesale & retail | 2023 |
| EZG Trans Ltd | Transport & logistics | 2018 |
| F C R B 1923 Adrian Ltd | Transport & logistics | 2021 |
| F H Atkinson (Fish Merchants) Limited | Manufacturing | 2003 |
| F Y T Enterprises Limited | Manufacturing | 2012 |
| F&S Property Holdings Ltd | Real estate | 2025 |
| F.E.S. (EX) Ltd | Professional & scientific | 2005 |
| F.L.A.G. (Supporting Youngsters With Special Needs) Limited | Other services | 2004 |
| F4 IT Ltd | Information & communication | 2019 |
| FAB Pads and Co 2017 Limited | Other services | 2017 |
| Fabric Etcetera Limited | Wholesale & retail | 2025 |
| Fabrication & Installation Limited | Manufacturing | 1990 |
| Fadzpak Store Ltd | Wholesale & retail | 2025 |
| Fair Energy Ltd | Other services | 2019 |
| Fairfield Controlec Ltd. | Manufacturing | 1988 |
| Fairway Found Ltd | Arts & recreation | 2025 |
| Fairwood Property Holdings Limited | Real estate | 2022 |
| Falcon Mews Management Limited | Extraterritorial | 2007 |
| Family-Centred Assessments Limited | Health & social care | 2024 |
| FAR East Sino Investments Ltd | Real estate | 2019 |
| FAR Spring Limited | Construction | 2014 |
| Fardel Group Ltd | Administrative & support | 2019 |
| Fardel Shipping Limited | Transport & logistics | 2009 |
| Farebrother Street News Limited | Wholesale & retail | 2013 |
| Farrell's Laundry Services Ltd | Other services | 2024 |
| Farrenburg Limited | Agriculture & fishing | 2024 |
| Farrow Contractors Ltd | Construction | 2021 |
| Farrow Estate Agents Ltd | Real estate | 2022 |
| Fashion C L Limited | Wholesale & retail | 2017 |
| Fashion Films Ltd | Professional & scientific | 2015 |
| Fast 2 Brothers Ltd | Transport & logistics | 2022 |
| Fast FIX Auto Ltd | Wholesale & retail | 2012 |
| Fast Track Car Wash Limited | Other services | 2004 |
| Fast-Form Systems Ltd | Manufacturing | 2013 |
| Fastcad Design Services Limited | Professional & scientific | 2013 |
| Fastline Shellfish Limited | Wholesale & retail | 2009 |
| Fastline Property Lettings Ltd | Real estate | 2021 |
| Fastpro Estimation Limited | Professional & scientific | 2023 |
| Fastway Transport Ltd | Transport & logistics | 2022 |
| FAT Lil's Developments Ltd | Construction | 2021 |
| Fault Find Ltd | Manufacturing | 2014 |
| Favour Foundation Ltd. | Health & social care | 2004 |
| Fawcett & Stone Limited | Real estate | 2025 |
| FB Wealth Management Limited | Financial services | 2010 |
| FB Wealth Management Trustees Limited | Administrative & support | 2021 |
| FBR Management Ltd | Financial services | 2017 |
| FBR Property Management Ltd | Real estate | 2019 |
| Fcjuk Ltd | Wholesale & retail | 2014 |
| FDC Enterprise Ltd | Transport & logistics | 2021 |
| Fell and Bean Limited | Wholesale & retail | 2023 |