| East Trans Warehousing Limited | Transport & logistics | 2015 |
| East Transportation Holdings Limited | Transport & logistics | 2005 |
| East Transportation Limited | Transport & logistics | 1995 |
| East Yorkshire Cast Stone Limited | Manufacturing | 2026 |
| Eastbay Limited | Construction | 1966 |
| Eastern Counties Scaffolding & Plant Limited | Wholesale & retail | 1972 |
| Eastern Pubs Limited | Real estate | 2006 |
| Eastfield Services (Aggregates) Limited | Agriculture & fishing | 2016 |
| Eastshore (Kingsway) Management Company Limited | Administrative & support | 2000 |
| Easy Grow Limited | Extraterritorial | 2005 |
| Easycleans (Marshchapel) Limited | Administrative & support | 2002 |
| Easywayflatable Ltd | Administrative & support | 2021 |
| EAT Your Greens Ltd | Professional & scientific | 2017 |
| Eazi-Move Mortgages Ltd | Financial services | 2019 |
| EBS Construction Services Ltd. | Construction | 2019 |
| ECG the Jesus Nation Church-East Midland CIC | Other services | 2025 |
| Echo Alfa Ltd | Wholesale & retail | 2012 |
| Echo Interior Design Ltd | Professional & scientific | 2012 |
| Echo Red Ltd | Professional & scientific | 2018 |
| ECI ENG Services Limited | Professional & scientific | 2021 |
| Eclh Ltd | Construction | 2023 |
| Eclipse Gymnastics Centre Limited | Arts & recreation | 2014 |
| Eclipse Property (HFX1) Ltd | Real estate | 2014 |
| Eco Heating Engineers Ltd | Construction | 2011 |
| Eco Shine Solutions Ltd | Administrative & support | 2023 |
| Eco-Sas Ltd | Construction | 2024 |
| Ecology & Forestry Limited | Other services | 2010 |
| Ecra Limited | Professional & scientific | 2022 |
| Edcc Ltd | Hospitality | 2018 |
| EDD Trucking Ltd | Transport & logistics | 2022 |
| Eden Altrincham Limited | Hospitality | 2024 |
| Eden Delight Limited | Wholesale & retail | 2025 |
| Eden Projects GY Ltd | Construction | 2023 |
| Edesia Consulting Limited | Professional & scientific | 2014 |
| Edge Avenue Capri Pizza Ltd | Hospitality | 2022 |
| Edge Avenue Pizza Shop Ltd | Hospitality | 2026 |
| Edgware Granulations Ltd | Water & waste | 2018 |
| Edident Ltd | Health & social care | 2017 |
| Edis Property Investments Ltd | Construction | 2018 |
| Edmonds Governance & Strategy Ltd | Professional & scientific | 2026 |
| Education Lincs Limited | Information & communication | 1998 |
| Edward Wright Consultancy Ltd | Administrative & support | 2015 |
| Edwin H. Davey (Limber) & Co. | Agriculture & fishing | 1953 |
| EEI Asset Protection Solutions Limited | Administrative & support | 2021 |
| Eezziflate Ltd | Administrative & support | 2000 |
| EF Distribution Ltd | Wholesale & retail | 2025 |
| Effectively Assure Limited | Professional & scientific | 2022 |
| Efia Properties Ltd | Real estate | 2023 |
| EGY Green Limited | Transport & logistics | 2015 |
| EIC Site Services Ltd | Construction | 2021 |
| Eigo Building Services Limited | Construction | 2021 |
| Eigo Building Services Recruitment Limited | Construction | 2025 |
| Eiss Group Ltd | Construction | 2022 |
| Eiss Ltd | Construction | 2022 |
| EJB Developments Grimsby Limited | Real estate | 2025 |
| Ejwaddison Ltd | Construction | 2026 |
| EJY Consultancy Limited | Professional & scientific | 2026 |
| Ekenecare Ltd | Health & social care | 2019 |
| EKO Coaching Ltd | Education | 2025 |
| Elaine Jones: Independent Social Care Assessments Ltd | Health & social care | 2023 |
| Elajam Limited | Financial services | 2020 |
| Elate Real Estate Ltd | Real estate | 2020 |
| Elba Care Limited | Health & social care | 2012 |
| Eleanor Fairfield Counselling Limited | Health & social care | 2023 |
| Electra Motion Ltd | Wholesale & retail | 2024 |
| Electric Vault Ltd | Wholesale & retail | 2017 |
| Electrical Inspection & Design Consultants Ltd | Professional & scientific | 2022 |
| Electrical Installation & Site Services Ltd | Construction | 2022 |
| Electrical Instrument Contractors Limited | Construction | 1990 |
| Electromek Services Limited | Manufacturing | 2018 |
| Electrotex Contracting Ltd | Construction | 2018 |
| Elecytech Limited | Construction | 2024 |
| Elegant Aesthetics by Becky Ltd | Other services | 2020 |
| Elegant Beds Limited | Wholesale & retail | 2015 |
| Elektor Ltd | Professional & scientific | 2017 |
| Elektronn Ltd | Manufacturing | 2021 |
| Element Group Ltd | Construction | 2018 |
| ELEVAT8 Limited | Information & communication | 2024 |
| Elevate Electrical & Renewables Ltd | Construction | 2023 |
| Elevate Joinery & Building Ltd | Construction | 2025 |
| Elevate PE Solutions Ltd | Education | 2026 |
| Elevate Souls Productions Ltd | Information & communication | 2024 |
| Elevation (GY) Holdings Limited | Financial services | 2021 |
| Elevation Cladding Limited | Construction | 2009 |
| Eleven Cafe Co. Limited | Hospitality | 2025 |
| Eleven Coffee Houses Ltd | Hospitality | 2022 |
| Elios Regenerative Developments Limited | Real estate | 2023 |
| Elipsa Ltd | Administrative & support | 2019 |
| Elite Asset Relocation Specialists Ltd | Transport & logistics | 2025 |
| Elite Business Management Solutions Ltd | Professional & scientific | 2021 |
| Elite Care Companions Ltd | Health & social care | 2026 |
| Elite Electrical Solutions (Lincs) Limited | Construction | 2020 |
| Elite Electrical Systems Ltd | Construction | 2023 |
| Elite Engineering Holdings Ltd | Real estate | 2017 |
| Elite Engineering Solutions Limited | Manufacturing | 2002 |
| Elite Fit LJ (Skegness) Limited | Arts & recreation | 2018 |
| Elite NW Ltd | Construction | 2018 |
| Elite Performance Athletics CIC | Arts & recreation | 2024 |
| Elite Plastering Services Grimsby Limited | Construction | 2014 |
| Elite Properties Linc's Ltd | Real estate | 2023 |