| Semi Consultancy Limited | Professional & scientific | 2020 |
| Shadykandi Ltd | Other services | 2023 |
| Shazia Noreen Ltd | Wholesale & retail | 2025 |
| Sheet Metal Precision Limited | Manufacturing | 2005 |
| Shields Safety Consultants Limited | Professional & scientific | 2006 |
| Shontaine Limited | Hospitality | 1996 |
| Shopmate Ltd | Construction | 2008 |
| SI VIS Amari Ltd | Wholesale & retail | 2010 |
| Sihhat Global Ltd | Wholesale & retail | 2024 |
| Silvon Software Limited | Information & communication | 1992 |
| Simcode IT Ltd | Professional & scientific | 2011 |
| Simplify Vehicles Limited | Administrative & support | 2010 |
| Simtec Installations Limited | Construction | 2005 |
| SJZ Holdings Limited | Financial services | 2024 |
| Skinclique Limited | Health & social care | 2019 |
| Sladelake Ltd | Other services | 2004 |
| Slice UK Solutions Limited | Administrative & support | 2019 |
| Smart Engineering Consulting Ltd | Information & communication | 2014 |
| Smile Hairdressing Limited | Other services | 2010 |
| Smith Brothers (Hyde) Limited | Manufacturing | 1990 |
| SNI Foods Ltd | Wholesale & retail | 2025 |
| Solar on Steroids Ltd | Information & communication | 2024 |
| Solo Store Ltd | Wholesale & retail | 2026 |
| Solutions 24-7 Limited | Professional & scientific | 2011 |
| South Yorkshire Roofing Limited | Construction | 1991 |
| Southern Contracts Limited | Professional & scientific | 1986 |
| Sovereign Transport Holdings Limited | Administrative & support | 2025 |
| Specialcrown Limited | Wholesale & retail | 1979 |
| Spectrum Alpha Property Partners LP | | 2005 |
| Spencross Limited | Professional & scientific | 1997 |
| Spice Master Trading Limited | Hospitality | 2014 |
| Spiralto Limited | Transport & logistics | 2003 |
| Sprint Loans Limited | Financial services | 1988 |
| SRA (Aggregates) Ltd | Wholesale & retail | 2018 |
| SSB Productions Ltd | Information & communication | 2018 |
| Standel Dawman Holdings Limited | Real estate | 1952 |
| Stanley Press Management Company Limited | Households | 2025 |
| Sterling Edge Ltd | Wholesale & retail | 2026 |
| Steuer Gregsson FD Limited | Professional & scientific | 2012 |
| Stockdales of Sale, Altrincham & District Ltd | Health & social care | 1978 |
| Stockport Sports Trust | Administrative & support | 2001 |
| Stuart FOX Studio Limited | Construction | 2013 |
| Sun Convenience Store and OFF Licence Ltd | Wholesale & retail | 2020 |
| Surgitrac Instruments UK Limited | Wholesale & retail | 1995 |
| Swiftscale Ltd | Information & communication | 2016 |
| Swiss Asset Manager Ltd | Financial services | 2008 |
| Synaxis Data Services Limited | Information & communication | 2001 |
| T & L Escapes Limited | Hospitality | 2019 |
| T G H Services Limited | Professional & scientific | 2007 |
| T.La Arts and Craft Gallery Limited | Wholesale & retail | 2002 |
| TAM United Logistic Ltd | Professional & scientific | 2020 |
| Tapa Wine Bar Ltd | Hospitality | 2011 |
| Tech Squared Limited | Information & communication | 2004 |
| Tectonic Consulting Limited | Professional & scientific | 2014 |
| Teknobu Ltd | Extraterritorial | 2024 |
| Terence Andrew Properties Limited | Real estate | 2023 |
| Terrapens Limited | Real estate | 2013 |
| THE Academy of E-Learning-Britain Limited | Information & communication | 2008 |
| THE Academy of Elearning and Consultations-Uk Ltd | Information & communication | 2023 |
| THE Barley MOW Penn Common Ltd | Hospitality | 2017 |
| THE Camlee Group Limited | Administrative & support | 2012 |
| THE Craven Group Limited | Professional & scientific | 1997 |
| THE Grading Club Ltd | Administrative & support | 2022 |
| THE Hatton Model Railway Company Limited | Financial services | 2017 |
| THE Kelbrook Mill Company Limited | Real estate | 1898 |
| THE Mann Organisation Limited | Professional & scientific | 1987 |
| THE Paddocks Hazel Grove Management Company Limited | Households | 2025 |
| THE PHE Group Limited | Construction | 2014 |
| THE Rainbow Inn Ltd | Hospitality | 2022 |
| THE Redeemed Christian Church of GOD (Rccg) Open Heavens Christian Centre, Wigan | Other services | 2025 |
| THE ST Edmunds Charity | Health & social care | 1997 |
| THE Swan and Cemetery Bury Limited | Hospitality | 2022 |
| THE Swift Organisation Ltd | Construction | 2006 |
| THE Vintage Hair Lounge Ltd | Other services | 2021 |
| Theemis Consulting Limited | Administrative & support | 2022 |
| Think Tank (UK) Limited | Information & communication | 2003 |
| This IS Union Ltd | Professional & scientific | 2017 |
| Three Twenty-Six Ltd | Wholesale & retail | 2025 |
| Three Worlds (Fwdg) Limited | Transport & logistics | 1984 |
| Thurloe Associates Ltd | Other services | 2015 |
| Tile Warehouse Imports Limited | Wholesale & retail | 2002 |
| Timjstone Ltd | Information & communication | 2016 |
| TJ Investment Property Ltd | Real estate | 2021 |
| Tmathematics Ltd | Financial services | 2025 |
| TMS Nuclear Consultants Ltd | Professional & scientific | 2009 |
| Toro Enterprise Ltd | Wholesale & retail | 2023 |
| Tourbillon Investment Management Ltd | Financial services | 2022 |
| Trafford Plaza Developments Limited | | 1980 |
| Trainers Stuff Limited | Wholesale & retail | 2025 |
| Training Industry Body | Administrative & support | 2025 |
| Transport a TUB Ltd | Transport & logistics | 2019 |
| Transport CRM Ltd | Information & communication | 2019 |
| Trattoria D'Agostino Limited | Hospitality | 2017 |
| Treelink Northwest Limited | Agriculture & fishing | 2007 |
| Trev Global Limited | Information & communication | 2008 |
| Trevor Wilson Dental Ceramics Ltd | Manufacturing | 2006 |
| Triclan Ltd | Real estate | 2004 |
| Trident Windows Limited | Manufacturing | 1990 |
| Tripzo Ltd | Administrative & support | 2026 |
| TRS Locums Ltd | Health & social care | 2018 |