| Savion Ltd | Construction | 2011 |
| Savvy Surveying Ltd. | Professional & scientific | 2023 |
| Saya Logistics Ltd | Transport & logistics | 2025 |
| Sayam Traders Ltd | Wholesale & retail | 2022 |
| Saygili Enterprises Ltd | Real estate | 2025 |
| Sazeda Group Ltd | Real estate | 2021 |
| SB & SQ Property Investment Limited | Real estate | 2025 |
| SB Fuel Tanks & Environmental Services Ltd | Other services | 2023 |
| Sbbosscollection Ltd | Extraterritorial | 2024 |
| SBD Facilities Management Ltd | Other services | 2025 |
| SBG Real Estate Ltd | Real estate | 2026 |
| SBM Electrical Ltd | Construction | 2018 |
| SBP Artificial Grass Ltd | Administrative & support | 2021 |
| SBP Installations Limited | Administrative & support | 2023 |
| SBS Sun Ltd | Transport & logistics | 2017 |
| Sbwn Limited | Administrative & support | 2022 |
| SC Resourcing and Supply Limited | Water & waste | 2026 |
| Scammell Commercial Limited | Wholesale & retail | 2001 |
| Scandinavian Trade Ltd | Wholesale & retail | 2019 |
| School of Academic and Behavioural Interventions Limited | Education | 2020 |
| School of Social Sustainability Ltd | Education | 2020 |
| Schoolfield Management Ltd | Construction | 2017 |
| Sclipi Drylining Ltd | Construction | 2018 |
| Scud Commercials Ltd | Wholesale & retail | 2006 |
| Scutaru Limited | Construction | 2022 |
| SD Driving Ltd | Construction | 2018 |
| SD GAS Services Ltd | Construction | 2023 |
| SD Utilities Ltd | Construction | 2021 |
| Sdda Ltd | Information & communication | 2022 |
| SDM Auto Ltd | Wholesale & retail | 2021 |
| SDR Marketing and Sales Limited | Professional & scientific | 2020 |
| SDU Telecoms Limited | Administrative & support | 2023 |
| Sea Pinks Ltd | Wholesale & retail | 2025 |
| Seafood Management Limited | Administrative & support | 2016 |
| Sealcode Limited | Information & communication | 2023 |
| Seas Homes Ltd | Real estate | 2022 |
| Seas Property Ltd | Real estate | 2019 |
| Seas Shelter Ltd | Real estate | 2023 |
| Season Clean Ltd | Administrative & support | 2021 |
| SEB Filote Ltd | Transport & logistics | 2016 |
| Sebanda Ltd | Manufacturing | 2022 |
| Sebastian Trans Ltd | Transport & logistics | 2020 |
| Second Chance Clothes UK Ltd | Wholesale & retail | 2025 |
| Secu Transport Ltd | Transport & logistics | 2023 |
| Secure Integration Ltd | Construction | 2023 |
| SECURE1ST Security Ltd | Administrative & support | 2017 |
| Securenet Limited | Information & communication | 2017 |
| Security & Standards Associates Limited | Information & communication | 2018 |
| Security Intervention K-9 Ltd | Other services | 2015 |
| Sedhon Ltd | Information & communication | 2008 |
| Sedhon Systems Limited | Information & communication | 2004 |
| Sedley Solutions Ltd | Professional & scientific | 2022 |
| Seeded Ltd | Information & communication | 2026 |
| Seisconnexions Associates Ltd | Mining & quarrying | 2025 |
| Seka Transfers Limited | Transport & logistics | 2025 |
| Selasie Ltd | Arts & recreation | 2015 |
| Selbycrest Limited | | 1983 |
| Select Energy Installations Limited | Construction | 2023 |
| Select Prestige Limited | Wholesale & retail | 2023 |
| Select Tints Ltd | Other services | 2024 |
| Selective Business Consultants Limited | Administrative & support | 2026 |
| Self Mastery Therapy Ltd | Health & social care | 2026 |
| Sellars Property Limited | Real estate | 2021 |
| Sellens IT Ltd | Information & communication | 2024 |
| Selothe Barber Ltd | Other services | 2020 |
| Semlik Ltd | Hospitality | 2018 |
| Send Cargo Couk Limited | Wholesale & retail | 2018 |
| Senessia Ltd | Health & social care | 2016 |
| Senisfaith Limited | Professional & scientific | 2017 |
| Sensation Tour's Ltd | Other services | 2016 |
| Sensi Homes Ltd | Real estate | 2024 |
| SEO Developers Ltd | Information & communication | 2018 |
| SEO Unix Ltd | Information & communication | 2026 |
| Septhur Options Limited | Wholesale & retail | 2025 |
| Serene Realty Ltd | Real estate | 2025 |
| Sergio Transport Ltd | Transport & logistics | 2024 |
| Serieux Solutions Limited | Information & communication | 2022 |
| Servon Ltd | Other services | 2025 |
| Setchase Limited | Other services | 2004 |
| Settled & Fulfilled Properties Limited | Real estate | 2020 |
| SEV Services Ltd | Construction | 2021 |
| Seventy X 7 Ltd | Wholesale & retail | 2024 |
| Sevviya Tech Ltd | Information & communication | 2025 |
| Sewing Supplies Direct Limited | Wholesale & retail | 2011 |
| SF Investments Ltd | Real estate | 2015 |
| SG Construction Group Ltd | Construction | 2022 |
| SG Sylvenn Limited | Construction | 2015 |
| SG93 Ltd | Transport & logistics | 2026 |
| SGK Catering Ltd | Hospitality | 2021 |
| SGL Sales Ltd | Wholesale & retail | 2023 |
| SH Auto Sales Limited | Wholesale & retail | 2025 |
| SHAD0W Realm Studios Ltd | Information & communication | 2026 |
| Shadow Team Preparedness Ltd | Administrative & support | 2020 |
| Shadow Trans Ltd | Transport & logistics | 2017 |
| Shahzadi Services Ltd | Administrative & support | 2000 |
| Shalokayim Services Ltd | Health & social care | 2014 |
| Shalomm Enterprises Ltd | Health & social care | 2025 |
| Shan and Krish Limited | Hospitality | 2024 |
| Shan Consultancy Ltd | Information & communication | 2025 |
| Share for Good Limited | Information & communication | 2025 |