| S&B Fuel Supplies Tech Ltd | Wholesale & retail | 2018 |
| S&J Elite Property Group Ltd | Real estate | 2026 |
| S&J Xpress Ltd | Transport & logistics | 2022 |
| S&S Transway Ltd | Transport & logistics | 2026 |
| S.A.W. Group of Companies Limited(The) | Professional & scientific | 1984 |
| S.Computing Ltd | Information & communication | 2019 |
| S.D.L Glass & Glazing Contracts Limited | Construction | 2010 |
| S.G. Protection Ltd | Financial services | 2019 |
| S.J.Evans Garden Care Ltd | Administrative & support | 2022 |
| S.T Heating Solutions Ltd | Construction | 2025 |
| S4SECURE Limited | Administrative & support | 2025 |
| S6ENERGY Limited | Construction | 2020 |
| S9MANU Enterprise Ltd | Wholesale & retail | 2019 |
| S9MANU Limited | Construction | 2019 |
| SA Consulting Group Ltd | Information & communication | 2022 |
| SA Fuel Services Limited | Wholesale & retail | 2018 |
| SA Shopfront and Shutter Limited | Construction | 2025 |
| Saaaba Services Limited | Administrative & support | 2024 |
| Saamkrishjon Limited | Administrative & support | 2018 |
| SABA7 Limited | Transport & logistics | 2020 |
| Sabbato Ltd | Hospitality | 2022 |
| Safa Furniture Ltd | Wholesale & retail | 2018 |
| Safari Healthcare Ltd | Health & social care | 2009 |
| Safe & Save Ltd | Wholesale & retail | 2019 |
| Safe Access and Security Fabrications Ltd | Manufacturing | 2025 |
| Safe Armor Security Services Ltd | Administrative & support | 2020 |
| Safe Cabling Ltd | Administrative & support | 2022 |
| Safe DIG Utilities Ltd | Administrative & support | 2017 |
| Safe Housing Investments Limited | Real estate | 2025 |
| Safe Quick Demolition Ltd | Construction | 2018 |
| Safe Services for Utilities Ltd | Administrative & support | 2022 |
| Safe Steps Contact Centre CIC | Health & social care | 2026 |
| Safe Traffic Management Ltd | Administrative & support | 2022 |
| Safeflow Ltd | Construction | 2025 |
| Safeguard Security Services Ltd | Other services | 2025 |
| Safesec Security Services Ltd | Administrative & support | 2023 |
| Safetrace Services Limited | Wholesale & retail | 2019 |
| Saffa Heating Limited | Other services | 2019 |
| Saffashaq Limited | Wholesale & retail | 2020 |
| Saffron Gardens Investments Ltd | Real estate | 2021 |
| Safi Taxi & Privets Hire Service Ltd | Transport & logistics | 2025 |
| Sagco Halal Meat Ltd | Wholesale & retail | 2020 |
| Sage & Beni Ltd | Real estate | 2025 |
| Saha Builders Ltd | Construction | 2023 |
| Sahadigitalbloom Ltd | Wholesale & retail | 2025 |
| Saigol Group Ltd | Transport & logistics | 2022 |
| Sailesh Dodia Ltd | Construction | 2023 |
| Saini Construction Limited | Construction | 1986 |
| Saini Projects Limited | Real estate | 2017 |
| Saint Paul Logistic Limited | Transport & logistics | 2017 |
| Saints' Thoughts Counselling Practice Ltd | Health & social care | 2026 |
| Saisam Properties Limited | Real estate | 2020 |
| SAJ Immigration Advisers Ltd | Professional & scientific | 2025 |
| Sakag Limited | Other services | 2014 |
| Saladeco Services Limited | Transport & logistics | 2023 |
| Salesprospers Holding Ltd | Information & communication | 2025 |
| Salino Ltd | Transport & logistics | 2024 |
| Salman Mehar Limited | Wholesale & retail | 2024 |
| SAM & KE Property Development Ltd | Construction | 2024 |
| Sam's Healthcare Ltd | Health & social care | 2014 |
| Samach Investments Limited | Real estate | 2023 |
| Samantha Foster Ltd | Hospitality | 2020 |
| Samary Catering & Events Limited | Hospitality | 2019 |
| Samcrossplus Services Limited | Transport & logistics | 2026 |
| Samebrothers Limited | Wholesale & retail | 2025 |
| Sameday City Logistics Ltd | Transport & logistics | 2026 |
| Sampros Ltd. | Professional & scientific | 2022 |
| Samsolin Limited | Professional & scientific | 2012 |
| Samson Akande Ltd | Wholesale & retail | 2025 |
| Samson's Fencing & Landscaping Ltd | Construction | 2020 |
| Samuelink Limited | Real estate | 2021 |
| SAN Trucking Ltd | Transport & logistics | 2025 |
| Sana Car Sales Ltd | Wholesale & retail | 2026 |
| Sanah Ltd | Wholesale & retail | 2012 |
| Sanah Properties Ltd | Real estate | 2022 |
| Sanapia Ltd | Manufacturing | 2024 |
| SANC2UARY Ltd | Health & social care | 2007 |
| Sandhu Brothers Courier Services Limited | Transport & logistics | 2025 |
| Sandy Lane Commercial Properties Limited | Administrative & support | 2024 |
| Sans Frontieres Associates Ltd | Professional & scientific | 2016 |
| Sans Pareil Solutions Ltd | Information & communication | 2024 |
| Sansaineel Limited | Wholesale & retail | 2010 |
| Santofix Limited | Administrative & support | 2019 |
| SAP Trans Ltd | Transport & logistics | 2018 |
| Sapphire Haven Ltd | Information & communication | 2025 |
| Sara Enterprises Ltd | Wholesale & retail | 2025 |
| Sarabjeet Transport Ltd | Transport & logistics | 2024 |
| Sardi Construction Ltd | Construction | 2020 |
| Sarga Construction Ltd | Construction | 2025 |
| Sarigul 18 Ltd | Hospitality | 2018 |
| Sarsaj Ltd | Professional & scientific | 2019 |
| Saru Trans Ltd | Transport & logistics | 2026 |
| SAS Consultants Limited | Professional & scientific | 2025 |
| Sasplayhome Limited | Wholesale & retail | 2026 |
| Satlink-Uk Ltd | Construction | 2015 |
| Satyabhama Limited | Wholesale & retail | 2024 |
| Savanna Car Hire Ltd | Administrative & support | 2019 |
| Savanna London Ltd | Wholesale & retail | 2024 |
| Savannah SV Solutions Ltd | Construction | 2015 |
| Savgrace Limited | Health & social care | 2024 |