| Summit Empire Group Ltd | Construction | 2026 |
| Sun & Moon Properties Limited | Real estate | 2018 |
| Sun Drive Hire & Logistics Limited | Transport & logistics | 2018 |
| Sun Kissed Sanctuary Limited | Other services | 2026 |
| Sunbeam Builders Ltd | Construction | 2022 |
| Sunday Launch Limited | Information & communication | 2003 |
| Sunny Luxuries Ltd | Real estate | 2025 |
| Sunremac UK Ltd | Manufacturing | 2015 |
| Sunshine Community Limited | Information & communication | 2018 |
| Supasell Ltd | Wholesale & retail | 2024 |
| Super Nuva Ltd | Manufacturing | 2013 |
| Superior Attire Limited | Wholesale & retail | 2017 |
| Superior Property Investments Ltd | Real estate | 2016 |
| Superior Sweets Ltd | Wholesale & retail | 2026 |
| Superson Transport Ltd | Transport & logistics | 2025 |
| Supersun Nutrition Limited | Manufacturing | 1958 |
| Surelet (Gloucester) Ltd | Real estate | 2003 |
| Surespec Consulting Services Limited | Professional & scientific | 2019 |
| Surestone Surfacing Ltd | Administrative & support | 2024 |
| Surface Engineering Services Limited | Administrative & support | 2017 |
| Surfing Smart Limited | Wholesale & retail | 2016 |
| Surya Chamak Limited | Wholesale & retail | 2024 |
| Susandan Limited | Transport & logistics | 2016 |
| Sushi Gloucester Ltd | Wholesale & retail | 2025 |
| Sussex Roofing Specialists Limited | Construction | 2025 |
| Sustainable Actions of People Ltd. | Professional & scientific | 2023 |
| Susurro Scents Ltd | Wholesale & retail | 2025 |
| Suvin Solutions Ltd | Information & communication | 2024 |
| SV Managed IT Ltd | Wholesale & retail | 2026 |
| SV Sportswear & Events Ltd | Arts & recreation | 2018 |
| Svsp Advanced Composites Limited | Extraterritorial | 2022 |
| Swallow Park Management (NO.1) Limited | Real estate | 1987 |
| Swan Planning Consultancy Limited | Administrative & support | 2012 |
| Swansea Digital Broadcasting Limited | Information & communication | 2023 |
| SWE Property Group Ltd | Real estate | 2026 |
| Sweet and Bitter Ltd | Manufacturing | 2017 |
| Sweet T’S Gloucester Ltd | Hospitality | 2021 |
| Sweetbriar House RTM Company Limited | Households | 2023 |
| Sweetbridge Alliance NFP, Ltd | Information & communication | 2022 |
| Sweetbridge NFP, Ltd | Information & communication | 2022 |
| Sweetop UK Ltd | Information & communication | 2021 |
| Sweetway DMC Ltd | Administrative & support | 2024 |
| Swenly Transport Solutions Ltd | Transport & logistics | 2012 |
| Swift Buck Express Ltd | Transport & logistics | 2021 |
| Swift Partnerships Limited | Professional & scientific | 2023 |
| Swift Removals & Storage UK Ltd | Transport & logistics | 2014 |
| Swift Spares Ltd | Wholesale & retail | 2020 |
| Swiftcartpro Ltd | Wholesale & retail | 2025 |
| Swiftdea Logistics Limited | Transport & logistics | 2025 |
| Swiftfit (Gloucester) Limited | Wholesale & retail | 1991 |
| Swiftfit Property Limited | Construction | 2024 |
| Swiftly Yours Ltd | Wholesale & retail | 2025 |
| Swiftride Cars Ltd | Transport & logistics | 2026 |
| SWIFTSHIP87 Limited | Wholesale & retail | 2026 |
| Swimtime Southwest Limited | Arts & recreation | 2010 |
| Swiss Calibre Ltd | Wholesale & retail | 2025 |
| SWJ Construction Ltd | Construction | 2015 |
| SWL Financial Consultancy Ltd | Professional & scientific | 2022 |
| Swplug Ltd | Wholesale & retail | 2023 |
| Sydney Studios Ltd | Arts & recreation | 2025 |
| Syed Ayan Ltd | Wholesale & retail | 2025 |
| Syhasventures Ltd | Wholesale & retail | 2026 |
| Sylk Medical and Business Consultancy Ltd | Information & communication | 2024 |
| Symphony Coatings Group Holdings Limited | Financial services | 2026 |
| Symphony Step 1 Limited | Financial services | 2025 |
| Symphony Step 5 Limited | Financial services | 2025 |
| Symphony Step 8 Limited | Financial services | 2025 |
| Sync Property Ltd | Financial services | 2022 |
| System 15 Limited | Information & communication | 2015 |
| System Force I.T. Limited | Information & communication | 2006 |
| Sysums Barbers LLP | | 2023 |
| Syte Travel Ltd | Administrative & support | 2020 |
| SZZ Real Estate Limited | Real estate | 2022 |
| T & D Rifleranges Limited | Construction | 2012 |
| T & I Electrical Services Limited | Construction | 2010 |
| T & M Real Estate Investments Ltd | Real estate | 2024 |
| T and T Howell Grounds and Tree Maintenance Ltd | Administrative & support | 2014 |
| T D Accounting Solutions Limited | Professional & scientific | 2025 |
| T D Tyres (Southwest) Limited | Wholesale & retail | 2022 |
| T D Tyres (Staunton) Limited | Wholesale & retail | 2024 |
| T D Tyres Limited | Wholesale & retail | 2017 |
| T D Tyres Property Limited | Real estate | 2019 |
| T E Wood Panelling Company Limited | Wholesale & retail | 2022 |
| T G Benfield Construction Ltd | Construction | 2025 |
| T G Designs Limited | Administrative & support | 2006 |
| T G Management Limited | Households | 2004 |
| T Gill Express Ltd | Transport & logistics | 2009 |
| T Hawkins Screeding Ltd | Construction | 2023 |
| T J H Contracting Limited | Construction | 2004 |
| T K Whitson Limited | Other services | 2006 |
| T N C Limited | Administrative & support | 1990 |
| T Nielsen & Co (Holdings) Limited | Financial services | 2015 |
| T Nielsen & Co Limited | Manufacturing | 1988 |
| T R Heating Ltd | Manufacturing | 2006 |
| T R J Marketing Limited | Administrative & support | 2009 |
| T S Lettings Ltd | Real estate | 2024 |
| T W Autoservices (Glos) Limited | Wholesale & retail | 1989 |
| T Whittaker Limited | Professional & scientific | 2008 |
| T&J Projects Limited | Administrative & support | 2019 |
| T-Hose Ecom Ltd | Wholesale & retail | 2025 |